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FADROZOLE

FADROZOLE structure

CAS No.: 102676-47-1

Chemical Name:: FADROZOLE

Synonyms: Afema;FAD286;CS-2710;FAD 286);CGS-16949;FADROZOLE;CGS-169494;FADROZOLE USP/EP/BP;Fadrozole (CGS 16949A;Fadrozole, 10 mM in DMSO

CBNumber:: CB3271421

Molecular Formula:: C14H13N3

Molecular Weight:: 223.27

MDL Number:: MFCD02313480

MOL File:: 102676-47-1.mol

MSDS File:: SDS

Last updated:2025-10-09 14:55:14

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FADROZOLE Properties

Melting point	0°C
Boiling point	0°C
Density	1.20
Flash point	0°C
storage temp.	2-8°C
solubility	DMSO : ≥ 100 mg/mL (447.89 mM)
form	Solid
pka	7.16±0.40(Predicted)
color	White to off-white
FDA UNII	H3988M64PU
EPA Substance Registry System	Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)- (102676-47-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06,GHS08
Signal word	Danger
Hazard statements	H301-H361
Precautionary statements	P281-P301+P310
Risk Statements	20/21/22
Safety Statements	22-24/25
RIDADR	3439

FADROZOLE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0002673	FADROZOLE 95.00%	102676-47-1	1G	$975.45	2021-12-16	Buy
American Custom Chemicals Corporation	API0002673	FADROZOLE 95.00%	102676-47-1	5G	$1855.51	2021-12-16	Buy
Arctom	AS554511	4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile ≥95%	102676-47-1	1g	$1339	2021-12-16	Buy
Arctom	AS554511	4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile ≥95%	102676-47-1	5mg	$39	2021-12-16	Buy
Ambeed	A428094	4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile 95+%	102676-47-1	5mg	$71	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0002673	1G	$975.45	Buy
API0002673	5G	$1855.51	Buy
AS554511	1g	$1339	Buy
AS554511	5mg	$39	Buy
A428094	5mg	$71	Buy

FADROZOLE Chemical Properties,Uses,Production

Uses

Antineoplastic

Definition

ChEBI: 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile is an imidazopyridine.

in vivo

Fadrozole hydrochloride is able to inhibit the aromatase-mediated androstenedione-induced uterine hypertrophy in immature female rats with an ED₅₀ of 0.03 mg/kg when given orally. In the same model, aminoglutethimide elicits the same effect with an ED₅₀ of 30 mg/kg when given orally^[1]. Fadrozole hydrochloride prevents the development of both benign and malignant spontaneus mammary neoplasns in female Sprague-Dawley rats. It also slows the spontaneous development of ptuitary pars dta mas in female rats, and reduces the of spontaneous hcu ar tumours in male and female rats^[2]. Administration of fadrozole in male and female mice suppresses the production of 17b-estradiol, accompanied with a 70% reduction in parasite burden. This protective effect is associated in male mice with a recovery of the specific cellular immune response. Interleukin-6 (IL-6) serum levels, and its production by splenocytes, is augmented by 80%, together with a 10-fold increase in its expression in testes of infected male mice. Fadrozole treatment returns these levels to baseline values^[3].

IC 50

Aromatase

FADROZOLE Preparation Products And Raw materials

Raw materials

Concentrated sulfuric acid

Preparation Products

FADROZOLE Suppliers

Global( 87)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32433	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20386	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9629	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24727	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39031	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58

Supplier	Advantage
Biochempartner	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
InvivoChem	58
HANGZHOU LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from FADROZOLE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-09	Fadrozole 102676-47-1	US $68.00-225.00 / mg		99.47%	10g	TargetMol Chemicals Inc.
2021-07-03	FADROZOLE USP/EP/BP 102676-47-1	US $1.10 / g	1g	99.9%	100 Tons Min	Dideu Industries Group Limited
2020-05-03	Fadrozole 102676-47-1	US $0.00-0.00 / Kg	1KG	99.0%	800 ton	Shaanxi Dideu Medichem Co. Ltd

Fadrozole
102676-47-1
US $68.00-225.00 / mg
99.47%
TargetMol Chemicals Inc.

FADROZOLE USP/EP/BP
102676-47-1
US $1.10 / g
99.9%
Dideu Industries Group Limited

Fadrozole
102676-47-1
US $0.00-0.00 / Kg
99.0%
Shaanxi Dideu Medichem Co. Ltd

FADROZOLE Spectrum

FADROZOLE(102676-47-1)¹HNMR

102676-47-1(FADROZOLE)Related Search:

Exemestane FADROZOLE HYDROCHLORIDE FADROZOLE 4-(1H-IMIDAZOL-1-YLMETHYL)BENZONITRILE

FADROZOLE 4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridine-5-yl)benzonitrile 4-[(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin)-5-yl]benzonitrile 4-[[5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin]-5-yl]benzonitrile 5,6,7,8-Tetrahydro-5-(4-cyanophenyl)imidazo[1,5-a]pyridine CGS-16949 Fadrozole Hydrochloride Hydrate Afema CGS-169494 4-(5，6，7，8-Tetrahydroimidazo[1，5-α]pyridin-5-y1)benzonitrile FAD 286) FAD286 Fadrozole (CGS 16949A CS-2710 Benzonitrile,4-(5,6,7,8-tetrahydroiMidazo[1,5-a]pyridin-5-yl)- 4-{5H,6H,7H,8H-iMidazo[1,5-a]pyridin-5-yl}benzonitrile FADROZOLE USP/EP/BP (Rac)-FAD286,inhibit,Fadrozole,CGS 16949A,Inhibitor,Aromatase Fadrozole, 10 mM in DMSO 102676-47-1