Reaxys ID: 26778003
- CAS No.
- 1604034-78-7
- Chemical Name:
- Reaxys ID: 26778003
- Synonyms
- Reaxys ID: 26778003;11H-Indolo[3,2-c]quinoline-9-carbonitrile, 2-methoxy-3-[2-(2-methoxyethoxy)ethoxy]-
- CBNumber:
- CB32729098
- Molecular Formula:
- C22H21N3O4
- Molecular Weight:
- 391.42
- MDL Number:
- MFCD32173205
- MOL File:
- 1604034-78-7.mol
Reaxys ID: 26778003 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ACHEMBLOCK | S86655 | 2-Methoxy-3-[2-(2-methoxy-ethoxy)-ethoxy]-11H-indolo[3,2-c]quinoline-9-carbonitrile 95% | 1604034-78-7 | 5MG | $390 | 2026-05-27 | Buy |
| ACHEMBLOCK | S86655 | 2-Methoxy-3-[2-(2-methoxy-ethoxy)-ethoxy]-11H-indolo[3,2-c]quinoline-9-carbonitrile 95% | 1604034-78-7 | 25MG | $1015 | 2026-05-27 | Buy |
| ACHEMBLOCK | S86655 | 2-Methoxy-3-[2-(2-methoxy-ethoxy)-ethoxy]-11H-indolo[3,2-c]quinoline-9-carbonitrile 95% | 1604034-78-7 | 100MG | $1715 | 2026-05-27 | Buy |
Reaxys ID: 26778003 Chemical Properties, Uses, Production
Uses
IRAK4-IN-29 is an IRAK4 inhibitor with good selectivity and low nanomolar activity. IRAK4-IN-29 can effectively block the TLR-mediated signal transduction pathway. IRAK4-IN-29 showed significant inhibitory effects in LPS- and R848-induced cytokine experiments. IRAK4-IN-29 can inhibit LPS-induced TNFα in an in vivo model, showing a similar phenotype to IRAK4 gene-deficient mice. IRAK4-IN-29 has good medicinal chemical properties, such as microsomal stability and solubility, showing potential clinical application value[1].
References
[1] Identification and optimization of indolo[2,3-c]quinoline inhibitors of IRAK4
Reaxys ID: 26778003 Preparation Products And Raw materials
Raw materials
Preparation Products
Reaxys ID: 26778003 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
View Latest Price from Reaxys ID: 26778003 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | PF-05388169
1604034-78-7
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- PF-05388169
1604034-78-7
- $1520.00-2500.00
- TargetMol Chemicals Inc.
