Quinoline-5-carboxaldehyde
- CAS No.
- 22934-41-4
- Chemical Name:
- Quinoline-5-carboxaldehyde
- Synonyms
- QUINOLINE-5-CARBALDEHYDE;AKOS BBS-00005336;5-Formylquinoline;CHEMBRDG-BB 4300479;RARECHEM AK ML 0025;5-Quinolinecarbaldehyde;5-QUINOLINECARBOXALDEHYDE;5-quinolinemethylaldehyde;QUINOLINE-5-CARBOXALDEHYDE;Quinoline-5-carbaldehyde(QUC)
- CBNumber:
- CB3323737
- Molecular Formula:
- C10H7NO
- Molecular Weight:
- 157.17
- MDL Number:
- MFCD00805835
- MOL File:
- 22934-41-4.mol
- MSDS File:
- SDS
| Melting point | 95-96°C |
|---|---|
| Boiling point | 314.3±15.0 °C(Predicted) |
| Density | 1.223±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 3.94±0.12(Predicted) |
| Appearance | Yellow to brown Solid |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Air Sensitive |
| BRN | 113095 |
| InChI | 1S/C10H7NO/c12-7-8-3-1-5-10-9(8)4-2-6-11-10/h1-7H |
| InChIKey | BNEVFKZLYCGDFG-UHFFFAOYSA-N |
| SMILES | O=Cc1cccc2ncccc12 |
| CAS DataBase Reference | 22934-41-4(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38-43 | |||||||||
| Safety Statements | 26-36/37/39-36/37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933499090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 |
|||||||||
| NFPA 704 |
|
Quinoline-5-carboxaldehyde price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR70131 | Quinoline-5-carboxaldehyde 98% | 22934-41-4 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR70131 | Quinoline-5-carboxaldehyde 98% | 22934-41-4 | 250mg | $30 | 2026-06-04 | Buy |
| Apolloscientific | OR70131 | Quinoline-5-carboxaldehyde 98% | 22934-41-4 | 1g | $73 | 2026-06-04 | Buy |
| Apolloscientific | OR70131 | Quinoline-5-carboxaldehyde 98% | 22934-41-4 | 5g | $355 | 2026-06-04 | Buy |
| Apolloscientific | OR70131 | Quinoline-5-carboxaldehyde 98% | 22934-41-4 | 25g | $1683 | 2026-06-04 | Buy |
Quinoline-5-carboxaldehyde Chemical Properties,Uses,Production
Uses
Quinoline-5-carboxaldehyde is used as a precursor in the preparation of pharmaceuticals.
Synthesis
4964-71-0
68-12-2
22934-41-4
General method: n-Butyllithium (2.5 M hexane solution, 300 μL, 0.72 mmol) was added slowly and dropwise to a solution of anhydrous THF (1.5 mL) of 5-bromoquinoline (100 mg, 0.48 mmol) at -78°C. The reaction solution turned red immediately. The reaction solution immediately turned red, followed by the addition of N,N-dimethylformamide (192 μL, 2.49 mmol). After maintaining the reaction temperature at -78 °C with stirring for 10 min, the reaction was quenched with deionized water (6 mL). The reaction mixture was poured into saturated aqueous sodium bicarbonate solution (10 mL) and extracted with ethyl acetate (3 × 10 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: n-hexane solution of 10% ethyl acetate) to give 5-quinolinecarboxaldehyde as a yellow solid in 53% yield.
References
[1] European Journal of Medicinal Chemistry, 2019, p. 290 - 320
Quinoline-5-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Shanghai Chenzhu Pharmaceutical Co., Ltd. | 13162380607 | 1696175688@qq.com | China | 834 | 55 |
View Lastest Price from Quinoline-5-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Quinoline-5-carboxaldehyde
22934-41-4
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-06-30 | Quinoline-5-carboxaldehyde
22934-41-4
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-12-27 | Quinoline-5-carboxaldehyde
22934-41-4
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Quinoline-5-carboxaldehyde
22934-41-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Quinoline-5-carboxaldehyde
22934-41-4
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- Quinoline-5-carboxaldehyde
22934-41-4
- $1.00
- 99%
- Career Henan Chemical Co
