6-Quinolinecarbaldehyde
- CAS No.
- 4113-04-6
- Chemical Name:
- 6-Quinolinecarbaldehyde
- Synonyms
- inecarbaL;AKOS AUF01714;AKOS BBS-00005338;6-Formylquinoline;6-quinolineMethanal;RARECHEM AK ML 0559;6-QUINOLINECARBALDEHYDE;QUINOLINE-6-CARBALDEHYDE;6-QUINOLINECARBOXALDEHYDE;QUINOLINE-6-CARBOXALDEHYDE
- CBNumber:
- CB5408618
- Molecular Formula:
- C10H7NO
- Molecular Weight:
- 157.17
- MDL Number:
- MFCD00805836
- MOL File:
- 4113-04-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Quinolinecarboxaldehyde >98.0%(GC)(T) | Q0097 | 1g | $110 |
| 6-Quinolinecarboxaldehyde >98.0%(GC)(T) | Q0097 | 5g | $387 |
| 6-Quinolinecarbaldehyde 97% | JK100124 | 5g | $421 |
| 6-QUINOLINECARBALDEHYDE 95.00% | CHM0027930 | 0.5G | $770 |
| 6-QUINOLINECARBALDEHYDE 95.00% | CHM0027930 | 5G | $1617 |
| More product size | |||
| Melting point | 74-75°C |
|---|---|
| Boiling point | 314.3±15.0 °C(Predicted) |
| Density | 1.223±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 4.13±0.10(Predicted) |
| form | powder to crystal |
| color | White to Yellow to Green |
| InChI | 1S/C10H7NO/c12-7-8-3-4-10-9(6-8)2-1-5-11-10/h1-7H |
| InChIKey | VUAOIXANWIFYCU-UHFFFAOYSA-N |
| SMILES | O=Cc1ccc2ncccc2c1 |
| CAS DataBase Reference | 4113-04-6(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P501-P270-P264-P301+P312+P330 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36/38-36 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| NFPA 704 |
|
6-Quinolinecarbaldehyde price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | Q0097 | 6-Quinolinecarboxaldehyde >98.0%(GC)(T) | 4113-04-6 | 1g | $110 | 2025-07-31 | Buy |
| TCI Chemical | Q0097 | 6-Quinolinecarboxaldehyde >98.0%(GC)(T) | 4113-04-6 | 5g | $387 | 2025-07-31 | Buy |
| Frontier Specialty Chemicals | JK100124 | 6-Quinolinecarbaldehyde 97% | 4113-04-6 | 5g | $421 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0027930 | 6-QUINOLINECARBALDEHYDE 95.00% | 4113-04-6 | 0.5G | $770 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0027930 | 6-QUINOLINECARBALDEHYDE 95.00% | 4113-04-6 | 5G | $1617 | 2021-12-16 | Buy |
6-Quinolinecarbaldehyde Chemical Properties,Uses,Production
Chemical Properties
white to light yellow powde
Synthesis
100516-88-9
4113-04-6
General procedure for the synthesis of quinoline-6-carbaldehyde from 6-hydroxymethylquinoline: method adapted from Meyers et al. (Meyers, A. G.; Zhong, B.; Movassaghi, M.; Kung, D. W.; Lanman, B. A.; Kwon, S. Tetrahedron Lett. 2000, 41, 1359-1362). Dess-Martin periodinane (2.57 g, 6.05 mmol) was added to a 0.28 M solution of 6-hydroxymethylquinoline (0.459 g, 2.88 mmol) in water-saturated dichloromethane (10 mL). The reaction mixture was stirred for 10 min and then dichloromethane (3 x 1 mL) was added in batches over 15 min. Subsequently, the reaction mixture was diluted with ether (10 mL) and 80% saturated aqueous sodium bicarbonate solution (10 mL) of sodium thiosulfate (7.87 g, 31.7 mmol) was added. The mixture was stirred rapidly for 45 minutes. The organic and aqueous layers were separated and the aqueous layer was extracted with ether (2 x 20 mL). The combined organic layers were washed sequentially with saturated aqueous sodium bicarbonate solution (30 mL), water (2 x 30 mL) and saturated sodium chloride solution (2 x 30 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography (30-60% ethyl acetate/hexane) to give 0.383 g (85%) of quinoline-6-carbaldehyde (S4a) as a white solid with a melting point of 76.2-76.5 °C. 1H NMR (400 MHz, CDCl3): δ 7.53 (dd, 1H, J = 4.4, 8.4 Hz), 8.18-8.23 (m, 2H ), 8.33 (dd, 1H, J = 2.0, 8.4 Hz), 8.36 (s, 1H), 9.05 (dd, 1H, J = 2.0, 4.4 Hz), 10.20 (s, 1H).13C NMR (100 MHz, CDCl3): δ 122.4, 126.8, 127.8, 130.9, 133.8, 134.4 , 137.6, 151.0, 153.3, 191.6. HRMS-FAB (m/z): calculated value of 157.0528 for [MH]+ C10H7NO; measured value of 157.0521.
References
[1] Patent: WO2004/7491, 2004, A1. Location in patent: Page 56
[2] Journal of the American Chemical Society, 2008, vol. 130, # 20, p. 6404 - 6410
[3] Patent: WO2009/75778, 2009, A2. Location in patent: Page/Page column 49; 50-51
[4] Patent: US2005/54670, 2005, A1. Location in patent: Page/Page column 27
6-Quinolinecarbaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8830 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 6-Quinolinecarbaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 6-Quinolinecarbaldehyde
4113-04-6
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 6-Quinolinecarbaldehyde
4113-04-6
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
