Z-Ala-Ala-Asn-AMC
- CAS No.
- 149697-16-5
- Chemical Name:
- Z-Ala-Ala-Asn-AMC
- Synonyms
- Z-AAN-AMC;Z-Ala-Ala-Asn-AMC;Z-ALA-ALA-ASN-MCA;BENZYLOXYCARBONYL-L-ALANYL-L-ALANYL-L-ASPARAGINE 4-METHYLCOUMARYL-7-AMIDE;L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;Benzyl ((S)-1-(((S)-1-(((S)-4-amino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1,4-dioxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)carbamate
- CBNumber:
- CB3331600
- Molecular Formula:
- C28H31N5O8
- Molecular Weight:
- 565.57
- MDL Number:
- MFCD02684274
- MOL File:
- 149697-16-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Z-Ala-Ala-Asn-AMC price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | MCA-3209-V | Z-Ala-Ala-Asn-AMC | 149697-16-5 | 5mg | $232.45 | 2026-06-04 | Buy |
| Biosynth | FA110589 | Z-Ala-Ala-Asn-AMC | 149697-16-5 | 25mg | $267.25 | 2026-06-04 | Buy |
| Biosynth | FA110589 | Z-Ala-Ala-Asn-AMC | 149697-16-5 | 50mg | $466 | 2026-06-04 | Buy |
| Biosynth | FA110589 | Z-Ala-Ala-Asn-AMC | 149697-16-5 | 100mg | $815 | 2026-06-04 | Buy |
| Biosynth | FA110589 | Z-Ala-Ala-Asn-AMC | 149697-16-5 | 250mg | $1635 | 2026-06-04 | Buy |
Z-Ala-Ala-Asn-AMC Chemical Properties, Uses, Production
Uses
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC[1].
References
[1] Stern L, Perry R, Ofek P, Many A, Shabat D, Satchi-Fainaro R. A novel antitumor prodrug platform designed to be cleaved by the endoprotease legumain. Bioconjug Chem. 2009;20(3):500-510. DOI:10.1021/bc800448u
[2] James C. Powers, et al. Propenoyl hydrazides. US7482379B2.
[3] Poreba M, et al. Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes. Cell Chem Biol. 2016;23(8):1023-1035. DOI:10.1016/j.chembiol.2016.05.020
Z-Ala-Ala-Asn-AMC Preparation Products And Raw materials
Raw materials
Preparation Products
Z-Ala-Ala-Asn-AMC Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
