ChemicalBook >> CAS DataBase List >>AA-115 (APG-115)

AA-115 (APG-115)

CAS No.
1818393-16-6
Chemical Name:
AA-115 (APG-115)
Synonyms
APG-115;Alrizomadlin;AA-115;AA-115 (APG-115);APG-115 (Alrizomadlin);Alrizomadlin, 10 mM in DMSO;Alrizomadlin/APG-115/AA-115;AA 115, APG 115, Alrizomadlin;4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid;4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid
CBNumber:
CB33339843
Molecular Formula:
C34H38Cl2FN3O4
Molecular Weight:
642.59
MDL Number:
MFCD32197175
MOL File:
1818393-16-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-20 20:20:01

AA-115 (APG-115) Properties

Boiling point 805.8±65.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 4.76±0.10(Predicted)
form Solid
color White to off-white
InChIKey YJCZPJQGFSSFOL-MNZPCBJKSA-N
SMILES C12(C(O)=O)CCC(NC([C@@H]3N(CC)C4([C@]5(C6=C(NC5=O)C=C(Cl)C=C6)[C@H]3C3=CC=CC(Cl)=C3F)CCCCC4)=O)(CC1)CC2
FDA UNII 15QAU0SI9J

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

AA-115 (APG-115) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth TXC39316 APG 115 1818393-16-6 5mg $1148.75 2026-06-05 Buy
Biosynth TXC39316 APG 115 1818393-16-6 10mg $1598.1 2026-06-05 Buy
Biosynth TXC39316 APG 115 1818393-16-6 25mg $2997 2026-06-05 Buy
Biosynth TXC39316 APG 115 1818393-16-6 50mg $4795 2026-06-05 Buy
ChemScene CS-0021621 Alrizomadlin 99.89% 1818393-16-6 5mg $152 2026-06-04 Buy
Product number Packaging Price Buy
TXC39316 5mg $1148.75 Buy
TXC39316 10mg $1598.1 Buy
TXC39316 25mg $2997 Buy
TXC39316 50mg $4795 Buy
CS-0021621 5mg $152 Buy

AA-115 (APG-115) Chemical Properties, Uses, Production

Uses

APG 115 is used in the treatment and prevention of osteoarthritis.

in vivo

Alrizomadlin (Delivered orally; 100 mg/kg; once daily; 10 days) enhances radiation antitumor effect in gastric adenocarcinoma in vivo[3].

Animal Model:Four-week-old male BALB/c athymic nude mice with MKN45 cells[3]
Dosage:100 mg/kg
Administration:Deliverer orally; once daily; 10 days
Result:Decreased xenograft tumor growth.

AA-115 (APG-115) Preparation Products And Raw materials

Raw materials

Preparation Products

AA-115 (APG-115) Suppliers

Global Suppliers ( 43)
Supplier Tel Email Country ProdList Advantage
Taizhou Zhongzhi Biotechnology Co., Ltd zhongzhipharma@126.c 15066129350 zhongzhipharma@126.com China 9963 58
Zhengzhou Haode Pharmaceutical Technology Co.,Ltd 18037386321 3330511471@qq.com China 498 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4859 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58

View Latest Price from AA-115 (APG-115) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Alrizomadlin pictures 2026-08-20 Alrizomadlin
1818393-16-6
$48.00-189.00 98.79% 10g TargetMol Chemicals Inc.
Alrizomadlin pictures 2026-07-27 Alrizomadlin
1818393-16-6
$48.00-189.00 98.79% 10g TargetMol Chemicals Inc.
  • Alrizomadlin pictures
  • Alrizomadlin
    1818393-16-6
  • $48.00-189.00
  • 98.79%
  • TargetMol Chemicals Inc.
  • Alrizomadlin pictures
  • Alrizomadlin
    1818393-16-6
  • $48.00-189.00
  • 98.79%
  • TargetMol Chemicals Inc.

AA-115 (APG-115) Spectrum

AA-115 (APG-115) AA-115 Bicyclo[2.2.2]octane-1-carboxylic acid, 4-[[[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-1'',2''-dihydro-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indol]-5'-yl]carbonyl]amino]- 4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid APG-115 (Alrizomadlin) Alrizomadlin/APG-115/AA-115 Alrizomadlin, 10 mM in DMSO 4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid AA 115, APG 115, Alrizomadlin Alrizomadlin APG-115 1818393-16-6