ChemicalBook >> CAS DataBase List >>AA-115 (APG-115)
AA-115 (APG-115)
- CAS No.
- 1818393-16-6
- Chemical Name:
- AA-115 (APG-115)
- Synonyms
- APG-115;Alrizomadlin;AA-115;AA-115 (APG-115);APG-115 (Alrizomadlin);Alrizomadlin, 10 mM in DMSO;Alrizomadlin/APG-115/AA-115;AA 115, APG 115, Alrizomadlin;4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid;4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid
- CBNumber:
- CB33339843
- Molecular Formula:
- C34H38Cl2FN3O4
- Molecular Weight:
- 642.59
- MDL Number:
- MFCD32197175
- MOL File:
- 1818393-16-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-08-20 20:20:01
| Boiling point | 805.8±65.0 °C(Predicted) |
|---|---|
| Density | 1.42±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 4.76±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | YJCZPJQGFSSFOL-MNZPCBJKSA-N |
| SMILES | C12(C(O)=O)CCC(NC([C@@H]3N(CC)C4([C@]5(C6=C(NC5=O)C=C(Cl)C=C6)[C@H]3C3=CC=CC(Cl)=C3F)CCCCC4)=O)(CC1)CC2 |
| FDA UNII | 15QAU0SI9J |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
AA-115 (APG-115) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | TXC39316 | APG 115 | 1818393-16-6 | 5mg | $1148.75 | 2026-06-05 | Buy |
| Biosynth | TXC39316 | APG 115 | 1818393-16-6 | 10mg | $1598.1 | 2026-06-05 | Buy |
| Biosynth | TXC39316 | APG 115 | 1818393-16-6 | 25mg | $2997 | 2026-06-05 | Buy |
| Biosynth | TXC39316 | APG 115 | 1818393-16-6 | 50mg | $4795 | 2026-06-05 | Buy |
| ChemScene | CS-0021621 | Alrizomadlin 99.89% | 1818393-16-6 | 5mg | $152 | 2026-06-04 | Buy |
AA-115 (APG-115) Chemical Properties, Uses, Production
Uses
APG 115 is used in the treatment and prevention of osteoarthritis.
in vivo
Alrizomadlin (Delivered orally; 100 mg/kg; once daily; 10 days) enhances radiation antitumor effect in gastric adenocarcinoma in vivo[3].
| Animal Model: | Four-week-old male BALB/c athymic nude mice with MKN45 cells[3] |
| Dosage: | 100 mg/kg |
| Administration: | Deliverer orally; once daily; 10 days |
| Result: | Decreased xenograft tumor growth. |
AA-115 (APG-115) Preparation Products And Raw materials
Raw materials
Preparation Products
AA-115 (APG-115) Suppliers
Global Suppliers ( 43)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Zhongzhi Biotechnology Co., Ltd | zhongzhipharma@126.c 15066129350 | zhongzhipharma@126.com | China | 9963 | 58 |
| Zhengzhou Haode Pharmaceutical Technology Co.,Ltd | 18037386321 | 3330511471@qq.com | China | 498 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
View Latest Price from AA-115 (APG-115) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-20 | Alrizomadlin
1818393-16-6
|
$48.00-189.00 | 98.79% | 10g | TargetMol Chemicals Inc. | ||
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2026-07-27 | Alrizomadlin
1818393-16-6
|
$48.00-189.00 | 98.79% | 10g | TargetMol Chemicals Inc. |
-

- Alrizomadlin
1818393-16-6
- $48.00-189.00
- 98.79%
- TargetMol Chemicals Inc.
-

- Alrizomadlin
1818393-16-6
- $48.00-189.00
- 98.79%
- TargetMol Chemicals Inc.
1818393-16-6 (AA-115 (APG-115)) Related Search:
(3S,3'S,4'S,5'S)-6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2-hydroxyethyl)-4'-nitrospiro[indoline-3,2'-pyrrolidin]-2-one
MI-773
Benzoic acid, 4-[[[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'',2''-dihydro-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indol]-5'-yl]carbonyl]amino]-, 2,2,2-trifluoroacetate (1:1)
MDM2-p53-IN-19
MD-224
1of2
AA-115 (APG-115)
AA-115
Bicyclo[2.2.2]octane-1-carboxylic acid, 4-[[[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-1'',2''-dihydro-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indol]-5'-yl]carbonyl]amino]-
4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid
4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid
APG-115 (Alrizomadlin)
Alrizomadlin/APG-115/AA-115
Alrizomadlin, 10 mM in DMSO
4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid
AA 115,
APG 115,
Alrizomadlin
Alrizomadlin
APG-115
1818393-16-6





