3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide
- CAS No.
- 724737-74-0
- Chemical Name:
- 3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide
- Synonyms
- Protein deglycase DJ-1 against-1;Benzamide, 3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]-
- CBNumber:
- CB33370372
- Molecular Formula:
- C24H23N3O4
- Molecular Weight:
- 417.46
- MDL Number:
- MOL File:
- 724737-74-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0137381 | Protein deglycase DJ-1 against-1 99.83% | 724737-74-0 | 5mg | $35 | 2026-06-04 | Buy |
| ChemScene | CS-0137381 | Protein deglycase DJ-1 against-1 99.83% | 724737-74-0 | 10mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-0137381 | Protein deglycase DJ-1 against-1 99.83% | 724737-74-0 | 25mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-0137381 | Protein deglycase DJ-1 against-1 99.83% | 724737-74-0 | 50mg | $152 | 2026-06-04 | Buy |
| ChemScene | CS-0137381 | Protein deglycase DJ-1 against-1 99.83% | 724737-74-0 | 100mg | $217 | 2026-06-04 | Buy |
3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide Chemical Properties,Uses,Production
Uses
Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson's disease research[1].
in vivo
Protein deglycase DJ-1 against-1 (compound-23; 1 mg/kg; IP; pretreatment one hour; daily; for 4 days) significantly restores MPTP induced locomotion, dopaminergic neuronal cell death and dopamine content in DJ-1(+/+) mice but not in DJ-1(-/-) mice[1].
| Animal Model: | Wild-type male C57BL/6 mice at 8, 11-12 and 9-12 weeks; DJ-1-knockout male mice at 11-13 weeks[1] |
| Dosage: | 1 mg/kg |
| Administration: | IP; pretreatment one hour; daily; for 4 days |
| Result: | Significantly restored MPTP (30 mg/kg; IP; One hour after injection) induced locomotion, dopaminergic neuronal cell death and dopamine content in DJ-1(+/+) mice but not in DJ-1(-/-) mice. |
References
[1] Kazuko Takahashi-Niki, et al. DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease. DOI:10.1016/j.jphs.2015.01.010
3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | sales@linyuepharm.com | China | 5731 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83453353 | nj.chemlin@chemlin.com.cn | CHINA | 852 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 | 690231469@qq.com | China | 8000 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | 2232176231@qq.com | China | 9997 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | Gsiyu@solarbio.com | China | 50460 | 58 |
View Lastest Price from 3,4,5-trimethoxy-N-[4-(8-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-22 | Protein deglycase DJ-1 against-1
724737-74-0
|
$29.00 | 97.23% | 10g | TargetMol Chemicals Inc. |
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- Protein deglycase DJ-1 against-1
724737-74-0
- $29.00
- 97.23%
- TargetMol Chemicals Inc.





