ZORUBICIN HCL
- CAS No.
- 36508-71-1
- Chemical Name:
- ZORUBICIN HCL
- Synonyms
- rubidaz;22050r.p.;nsc-164011;ZORUBICIN HCL;rp22,050hydrochloride;ZORUBICIN HCL USP/EP/BP;rubidazone,monohydrochloride;daunorubicin,benzoylhydrazone,monohydrochloride;benzoicacidhydrazide,3-hydrazonewithdaunorubicin,monohydrochloride;(2S-cis)-Benzoic acid[1-[4-[(3-amino-2，3，6-trideoxy-α-L-lyxo-hex-opyranosyl)oxy]-1，2，3，4，6，11-hexahydro-2，5，12-trihydroxy-7-methoxy-6，11-dioxo-2-napthacenyl]ethylidene]hydrazide hydroehloride
- CBNumber:
- CB3339363
- Molecular Formula:
- C34H36ClN3O10
- Molecular Weight:
- 682.12
- MDL Number:
- MFCD00941450
- MOL File:
- 36508-71-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Zorubicin hydrochloride | FZ76682 | 1mg | $150 |
| Zorubicin hydrochloride | FZ76682 | 2mg | $150 |
| Zorubicin hydrochloride | FZ76682 | 5mg | $194.7 |
| Zorubicin hydrochloride | FZ76682 | 10mg | $311.5 |
| Zorubicin hydrochloride | FZ76682 | 25mg | $405.5 |
| alpha | D20 -50° (c = 0.2 in water) |
|---|---|
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Orange to Dark Red |
| Stability | Light Sensitive |
| FDA UNII | WXM8D9M6DE |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in mice (mg/kg): 13.66 s.c., 4.42 i.p., 8.50 i.v. (Maral, 1972) |
|---|
ZORUBICIN HCL price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FZ76682 | Zorubicin hydrochloride | 36508-71-1 | 1mg | $150 | 2026-06-04 | Buy |
| Biosynth | FZ76682 | Zorubicin hydrochloride | 36508-71-1 | 2mg | $150 | 2026-06-04 | Buy |
| Biosynth | FZ76682 | Zorubicin hydrochloride | 36508-71-1 | 5mg | $194.7 | 2026-06-04 | Buy |
| Biosynth | FZ76682 | Zorubicin hydrochloride | 36508-71-1 | 10mg | $311.5 | 2026-06-04 | Buy |
| Biosynth | FZ76682 | Zorubicin hydrochloride | 36508-71-1 | 25mg | $405.5 | 2026-06-04 | Buy |
ZORUBICIN HCL Chemical Properties,Uses,Production
Chemical Properties
Orange-red crystalline powder from ethanol. [α]D20-50° (C=0.2, water).UV maximum absorption (methanol): 232.5, 253, 480, 495 nm (ε40225, 35300, 10480, 10300). Acute toxicity LD50 mice (mg/kg): 13.66 subcutaneous, 4.42 intraperitoneal, 8.50 intravenous.
Originator
Zorubicin Hydrochloride,ZYF Pharm Chemical
Uses
Antineoplastic.
Uses
Zorubicin Hydrochloride is an anthracycline anti-cancer drug related to Daunorubicin (D194500).
Manufacturing Process
9.024 g daunorubicin-hydrochloride (its preparation and physicochemical properties have been described in British Patent Specification No 985 598) was dissolved in 800 ml ethanol and mixed with 2.5 ml acetic acid and 2.162 g benzoyl hydrazide and heated for 24 hours at 60°C. On cooling the obtained precipitate was filtered off, washed with 100 ml of ethanol and dried in vacuum at 20°C. It was dissolved in water and small quantity of insoluble product was filtered off, the filtrate was lyophilized. (1-(4-((3-Amino-2,3,6- trideoxy-α,L-lyxohexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12- trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide dihydrochloride (zorubicin) was obtained as red-orange crystalline powder; [α] D 20 = -50° (c=0.2 in water). The compound may be employed in the form of different non-toxic salts such as benzoates, fumarates, maleates, tartrates and so on. The best among these compounds proves to be daunorubicin benzoylhydrazone (rubidazone), which is less cardiotoxic (French Pat. No. 1,578,722 published in 1967, Class CO7d).
Therapeutic Function
Antineoplastic, Antileukemic
ZORUBICIN HCL Preparation Products And Raw materials
ZORUBICIN HCL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Jinan Renyuan Chemical Co., Ltd. | 0531-86128689 18396852370 | 1840274076@qq.com | China | 299 | 58 |
| Changzhou Xianglong Pharmaceutical Technology Co., Ltd., | 18915873328 18915873328 | sales@xianglongpharm.com | China | 11049 | 58 |
36508-71-1(ZORUBICIN HCL)Related Search:
1of4
