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2'-Iodohippuric acid

CAS No.
147-58-0
Chemical Name:
2'-Iodohippuric acid
Synonyms
OIH;2-Iodhippursure;iodohippuricacid;2-IodohippuricAci;2-IODOHIPPURIC ACID;O-IODOHIPPURIC ACID;2-Lodohippuric Acid;2'-Iodohippuric acid;2-IodohippuricAcid>(2-IODOBENZOYL)GLYCINE
CBNumber:
CB3345959
Molecular Formula:
C9H8INO3
Molecular Weight:
305.07
MDL Number:
MFCD00002694
MOL File:
147-58-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:00

2'-Iodohippuric acid Properties

Melting point 170-172 °C (lit.)
storage temp. Store below +30°C.
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
BRN 1877943
InChI 1S/C9H8INO3/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)
InChIKey CORFWQGVBFFZHF-UHFFFAOYSA-N
SMILES OC(=O)CNC(=O)c1ccccc1I
CAS DataBase Reference 147-58-0(CAS DataBase Reference)
FDA UNII 3Y68K91A3M
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HS Code  2924 29 70
Storage Class 11 - Combustible Solids

2'-Iodohippuric acid price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1344305 o-Iodohippuric acid United States Pharmacopeia (USP) Reference Standard 147-58-0 100mg $382 2026-04-30 Buy
Sigma-Aldrich 106577 2-Iodohippuric acid 98% 147-58-0 10g $110 2026-04-30 Buy
Sigma-Aldrich 8.20736 o-Iodohippuric acid for synthesis 147-58-0 10g $444 2022-05-15 Buy
Sigma-Aldrich 8.20736 o-Iodohippuric acid for synthesis 147-58-0 25g $1090 2022-05-15 Buy
TCI Chemical I0446 2-Iodohippuric Acid >99.0%(T) 147-58-0 5g $53 2026-04-30 Buy
Product number Packaging Price Buy
1344305 100mg $382 Buy
106577 10g $110 Buy
8.20736 10g $444 Buy
8.20736 25g $1090 Buy
I0446 5g $53 Buy

2'-Iodohippuric acid Chemical Properties, Uses, Production

Synthesis

Synthetic Route of 2-Iodohippuric Acid

General/Typical Procedure: Preparation of N-2-bromobenzoylglycine: Glycine (0.948 g, 12.628 mmol) was dissolved in water (50 mL), and then dissolved in an aqueous solution of 2-bromobenzoyl chloride (0.649 g, 2.957 mmol). NaOH solution (0.380 g, 9.500 mmol) was added to this solution in portions to maintain a slightly alkaline pH of the mixture. After each addition, the mixture was vigorously stirred. Crushed ice was added to the solution, followed by dropwise addition of concentrated HCl until the mixture was acidified (pH 2-3).

The mixture was then cooled in a refrigerator, filtered, and the precipitate was washed several times with water to remove excess glycine. It was then dried under vacuum to give N-2-bromobenzoylglycine as a white crystalline solid (yield 0.565 g, 74%). Preparation of N-2-iodobenzoylglycine: As with N-2-bromobenzoylglycine, glycine (2.431 g, 32.383 mmol), iodobenzoyl chloride (2.157 g, 8.950 mmol), and NaOH (0.712 g, 17.800 mmol) were reacted to give N-2-iodobenzoylglycine as a white crystalline solid (yield 1.531 g, 62%).

Uses

o-Iodohippuric Acid is used as a probe to measure renal function and clearance.

Definition

ChEBI: 2-iodohippuric acid is a member of the class of benzamides resulting from the formal condensation of the carboxy group of 2-iodobenzoic acid with the amino group of glycine. It is a N-acylglycine, an organoiodine compound and a member of benzamides. It is a conjugate acid of a 2-iodohippurate.

reaction suitability

reaction type: solution phase peptide synthesis

2'-Iodohippuric acid Preparation Products And Raw materials

2'-Iodohippuric acid Suppliers

Global Suppliers ( 96)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
TCI AMERICA 800-4238616 sales@tciamerica.com Americas 23636 75

View Latest Price from 2'-Iodohippuric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Iodohippuric Acid pictures 2026-08-08 2-Iodohippuric Acid
147-58-0
$32.00-72.00 99.26% 10g TargetMol Chemicals Inc.
2-iodohippuric acid pictures 2026-06-30 2-iodohippuric acid
147-58-0
1KG 98% 10000KG Shaanxi Dideu New Materials Co. Ltd
2'-IODOHIPPURIC ACID pictures 2026-05-26 2'-IODOHIPPURIC ACID
147-58-0
$1.50 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
o-Iodohippuric Acid (100 mg) o-Iodohippuric acid for synthesis 2-IODOHIPPURIC ACID (2-IODOBENZOYL)GLYCINE O-IODOHIPPURIC ACID N-(2-IODOBENZOYL)GLYCINE Glycine,N-(2-iodobenzoyl)- iodohippuricacid 2-[(2-Iodobenzoyl)amino]acetic acid OIH 2-[(2-iodophenyl)carbonylamino]ethanoic acid 2-Iodohippuric acid ,98% 2-IodohippuricAcid> 2-IodohippuricAci o-Iodohippuric Acid (1344305) 2-Iodohippuric Acid,Inhibitor,2[(2iodophenyl)formamido]acetic acid,2 [(2 iodophenyl)formamido]acetic acid,inhibit ortho-iodohippuric acid 2-(2-Iodobenzamido)acetic acid 2-Iodohippuric Acid, 10 mM in DMSO 2-Iodhippursure 2-Lodohippuric Acid 2'-Iodohippuric acid 147-58-0 C9H8INO3 IC6H4CONHCH2CO2H Amino Acid Derivatives Peptide Synthesis Specialty Synthesis