Propargite
- CAS No.
- 2312-35-8
- Chemical Name:
- Propargite
- Synonyms
- propargil;BPPS;OMITE;comite;RETADOR;d014;do14;Omit;omait;progi
- CBNumber:
- CB3346491
- Molecular Formula:
- C19H26O4S
- Molecular Weight:
- 350.47
- MDL Number:
- MFCD00072448
- MOL File:
- 2312-35-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | <25 °C |
|---|---|
| Boiling point | 454.45°C (rough estimate) |
| Density | 1.1604 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.5220 (estimate) |
| Flash point | 71 °C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Hexane (Slightly) |
| form | Viscous Liquid |
| color | Dark/light brown |
| Water Solubility | 215μg/L at 20℃ |
| Merck | 13,7900 |
| BRN | 6934289 |
| Henry's Law Constant | 1.5×101 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Major Application |
agriculture cleaning products cosmetics environmental food and beverages personal care |
| InChI | 1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 |
| InChIKey | ZYHMJXZULPZUED-UHFFFAOYSA-N |
| SMILES | CC(C)(C)c1ccc(OC2CCCCC2OS(=O)OCC#C)cc1 |
| LogP | 5.7 |
| CAS DataBase Reference | 2312-35-8(CAS DataBase Reference) |
| EWG's Food Scores | 5 |
| FDA UNII | 30M429ANKL |
| Proposition 65 List | Propargite |
| NIST Chemistry Reference | Propargite(2312-35-8) |
| EPA Substance Registry System | Propargite (2312-35-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H330-H351-H410 |
| Precautionary statements | P202-P273-P280-P302+P352-P304+P340+P310-P305+P351+P338 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | T;N,N,T |
| Risk Statements | 23-38-40-41-50/53 |
| Safety Statements | 26-36/37/39-45-60-61 |
| RIDADR | UN 2810 |
| WGK Germany | 3 |
| RTECS | WT2900000 |
| HazardClass | 9 |
| PackingGroup | III |
| HS Code | 29209090 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 2 Inhalation Aquatic Acute 1 Aquatic Chronic 1 Carc. 2 Eye Dam. 1 Skin Irrit. 2 |
| Hazardous Substances Data | 2312-35-8(Hazardous Substances Data) |
| Toxicity | LD50 in male, female rats (mg/kg): 1480, 1480 orally; 250, 680 dermally (Gaines); LC50 in rainbow trout, bluegill sunfish (ppb): >100, 31 (Stone) |
| REACH Registrations | Inactive |
Propargite price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 32051 | Propargite PESTANAL?, analytical standard, technical mixture | 2312-35-8 | 100MG | $68.7 | 2026-04-30 | Buy |
| TRC | TRC-P762500-25G | Propargite(Mixture of Diastereomers) | 2312-35-8 | 25g | $1603 | 2026-06-03 | Buy |
| TRC | TRC-P762500-1G | Propargite(Mixture of Diastereomers) | 2312-35-8 | 1g | $208 | 2026-06-03 | Buy |
| Usbiological | 166028 | Propargite | 2312-35-8 | 1g | $418 | 2026-06-03 | Buy |
| TRC | TRC-P762500-10G | Propargite(Mixture of Diastereomers) | 2312-35-8 | 10g | $1106 | 2026-06-03 | Buy |
Propargite Chemical Properties,Uses,Production
Description
The pesticide omite pricipally acts as an irritant. Contact dermatitis was reported in 40 of 47 agricultural workers using it.
Chemical Properties
Insoluble in water.
Uses
Propargite is a pesticide used to control mite and is used on various crops from cotton to corn.
Uses
Acaricide for fruits, vegetables, row crops.
Definition
ChEBI: Propargite is a sulfite ester and a terminal acetylenic compound. It has a role as a sulfite ester acaricide.
Production Methods
The industrial synthesis of propargite begins with the preparation of 2-(4-tert-butylphenoxy)cyclohexanol, which is synthesised by reacting 4-tert-butylphenol with cyclohexene oxide under acidic conditions to form the ether linkage. This intermediate is then esterified with propargyl sulfonyl chloride in the presence of a base such as triethylamine or pyridine, forming the sulfonate ester. The reaction is typically carried out in organic solvents like dichloromethane or toluene under controlled temperature and pH conditions to ensure high yield and purity. After synthesis, the crude product is purified through distillation or solvent extraction.
General Description
Propargite is a dark colored liquid. Propargite is a wettable powder or water emulsifiable liquid. Propargite can cause illness by inhalation, skin absorption and/or ingestion. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Since Propargite is a liquid Propargite can easily penetrate the soil and contaminate groundwater and nearby streams. Propargite is used as a pesticide. Practically insoluble in water (10.5 mg/L). Used as an acaricide.
Air & Water Reactions
Practically insoluble in water (10.5 mg/L). Slowly reacts with water to form sulfur dioxide and alcohols; reaction is more rapid under basic or acidic conditions.
Reactivity Profile
Propargite is a sulfite ester. As an ester, Propargite will hydrolyze to form sulfur dioxide and alcohols; reaction is more rapid under basic conditions. Propargite may react exothermically with acids to generate alcohols. Heat will be generated by interaction with basic or caustic solutions. Flammable hydrogen is generated by mixing with alkali metals and hydrides.
Health Hazard
INHALATION: Irritation of mucous membranes. EYES: Irritation, may be severe. SKIN: Irritation.
Flammability and Explosibility
Non flammable
Agricultural Uses
Miticide and acaricide: Pending for use in EU countries. A U.S. EPA restricted Use Pesticide (RUP). Used on a variety of bearing and non-bearing food crops and non-food sites. Grapes, walnuts, almonds, nectarines and mint are the most treated crops. Other crops include alfalfa, avocados, beans, boysenberries, carrots, cherries, citrus, corn, currants, dates, filberts, grapefruit, jojoba, grapes, hops, peanuts, sugar beets, cotton and ornamentals.
Trade name
COMITE II®; COMITE® AGRICULTURAL MITICIDE; D-014®; DIBROM OMITE®; DICTATOR®; NAUGATUCK® D-014; OMAIT®; OMITE®; OMITE® 570EW; RED-TOP®[C]; UNIROYAL® D-014; U.S. RUBBER D-014®
Contact allergens
The pesticide omite principally acts as an irritant. Contact dermatitis was reported in 40 of 47 agricultural workers using Omite.
Mechanism of action
Non-systemic with contact action, inhibits oxidative phosphorylation. Inhibitor of mitochondrial ATP synthase.
Safety Profile
Poison by skin contact. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of SOx. See also ESTERS and SULFUROUS ACID.
Pesticide Type
Acaricide; Insecticide
Propargite Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Rosi Chemical Co., Ltd. | -- | sales@lerui.com | China | 14 | 50 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 997 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
View Lastest Price from Propargite manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | Propargite
2312-35-8
|
$38.00-98.00 | 98.81% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-14 | Propargite
2312-35-8
|
1box | 90% | 20KL | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2020-04-28 | Propargite
2312-35-8
|
1KG | 99.0% | 500 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Propargite
2312-35-8
- $38.00-98.00
- 98.81%
- TargetMol Chemicals Inc.
-
- Propargite
2312-35-8
- $0.00
- 90%
- Qingdao Trust Agri Chemical Co.,Ltd
-
- Propargite
2312-35-8
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
