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Z-TRP-OBZL

CAS No.
69876-37-5
Chemical Name:
Z-TRP-OBZL
Synonyms
Cbz-Trp-OBzl;Z-TRP-OBZL;Cbz-Trp-Obn;Z-L-Trp-OBzl;Z-L-TRYPTOPHAN BENZYL ESTER;N-a-Z-L-tryptophanbenzylester;Nα-Z-L-tryptophan benzyl ester;N-α-Z-L-tryptophan benzyl ester;N-cbz-L-tryptophan benzyl ester;N-.ALPHA.-CBZ-L-TRYPTOPHAN BENZYL ESTER
CBNumber:
CB3358438
Molecular Formula:
C26H24N2O4
Molecular Weight:
428.48
MDL Number:
MFCD00191163
MOL File:
69876-37-5.mol
MSDS File:
SDS
Last updated:2026-05-28 05:23:18

Z-TRP-OBZL Properties

Melting point 105-108℃
Boiling point 656.7±55.0 °C(Predicted)
Density 1.266±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
form Powder
pka 10.93±0.46(Predicted)
color White to off-white
optical activity 7.70°(C=0.01g/mL, CHCL3, 20°C, 589nm)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Z-TRP-OBZL price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 291169 N-alpha-Z-L-tryptophan benzyl ester Asreported 69876-37-5 2g $353 2026-06-03 Buy
Usbiological 291169 N-alpha-Z-L-tryptophan benzyl ester Asreported 69876-37-5 5g $523 2026-06-03 Buy
Usbiological 291169 N-alpha-Z-L-tryptophan benzyl ester Asreported 69876-37-5 10g $716 2026-06-03 Buy
Usbiological 291169 N-alpha-Z-L-tryptophan benzyl ester Asreported 69876-37-5 25g $984 2026-06-03 Buy
ChemPep 411802-5G Z-Trp-OBzl 69876-37-5 5g $293 2026-06-04 Buy
Product number Packaging Price Buy
291169 2g $353 Buy
291169 5g $523 Buy
291169 10g $716 Buy
291169 25g $984 Buy
411802-5G 5g $293 Buy

Z-TRP-OBZL Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Synthesis

Benzyl alcohol

100-51-6

N-Cbz-L-Tryptophan

7432-21-5

Z-TRP-OBZL

69876-37-5

GENERAL STEPS: To a stirred suspension of (S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoic acid (2.45 g, 7.2 mmol) in 10 mL of anhydrous dichloromethane, 4-dimethylaminopyridine (DMAP, 88 mg, 0.72 mmol) and benzyl alcohol (1.28 g, 11.8 mmol) were added. A 5 mL solution of N,N'-dicyclohexylcarbodiimide (DCC, 1.48 g, 7.2 mmol) in dichloromethane was slowly added at 0 °C. The reaction was carried out at 0 °C with the addition of N,N'-dicyclohexylcarbodiimide (DCC, 1.48 g, 7.2 mmol). The reaction mixture was slowly warmed to room temperature and stirred overnight. The white precipitate was removed by filtration and the solvent was subsequently removed by distillation under reduced pressure to afford the colorless oily product Cbz-L-tryptophan benzyl ester (3 g, 98%). The product had a rotativity of [α]D20 = +50 (c = 1.0, CHCl3, 365 nm). Thin layer chromatography (TLC) showed Rf = 0.29 (ethyl acetate:hexane = 1:2).1H NMR (400 MHz, CDCl3) δ: 8.26 (br, 1H), 7.56 (d, J = 8.0 Hz, 1H), 7.41-7.33 (m, 9H), 7.26-7.20 (m, 3H), 7.12 (t, J = 8.0 Hz , 1H), 6.76 (d, J = 2.0 Hz, 1H), 5.47 (d, J = 8.0 Hz, 1H), 5.18-5.10 (m, 4H), 4.82 (q, J = 8.0 Hz, 1H), 3.34 (d, J = 5.1 Hz, 2H).13C NMR (100 MHz, CDCl3) δ: 171.8, 155.8 , 136.1, 136.0, 135.1, 128.5, 128.4, 128.3, 128.0, 127.5, 127.4, 126.9, 122.9, 122.0, 119.5, 118.5, 111.2, 109.4, 67.1, 66.8, 54.6, 27.8.Fourier transform infrared (FTIR) spectroscopy ( FTIR, pure sample) showed absorption peaks located at 3395, 3343, 1742, 1458, 1377, 721 cm-1. High resolution mass spectrometry (HRMS, ESI) calculated value of C20H20O4N2 [M + H]+ was 429.1814 and measured value was 429.1821.

References

[1] Patent: US2011/269972, 2011, A1. Location in patent: Page/Page column 20

Z-TRP-OBZL Preparation Products And Raw materials

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
NINGBO INNO PHARMCHEM CO.,LTD. 86-574-27787657 info@dearchem.com China 4607 58
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55

View Lastest Price from Z-TRP-OBZL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Z-TRP-OBZL pictures 2019-07-06 Z-TRP-OBZL
69876-37-5
$1.00 1KG 99% 1ton Career Henan Chemical Co
Z-TRP-OBZL pictures 2019-07-06 Z-TRP-OBZL
69876-37-5
$1.00 1KG 99% 20kg Career Henan Chemical Co
  • Z-TRP-OBZL pictures
  • Z-TRP-OBZL
    69876-37-5
  • $1.00
  • 99%
  • Career Henan Chemical Co
  • Z-TRP-OBZL pictures
  • Z-TRP-OBZL
    69876-37-5
  • $1.00
  • 99%
  • Career Henan Chemical Co

Z-TRP-OBZL Spectrum

N-.ALPHA.-CBZ-L-TRYPTOPHAN BENZYL ESTER N-Carbobenzyloxy-L-tryptphan benzyl ester (S)-benzyl 2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate Benzyl (S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate N-[(Phenylmethoxy)carbonyl]-L-tryptophan phenylmethyl ester N-ALPHA-CARBOBENZOXY-L-TRYPTOPHAN ALPHA-BENZYL ESTER Z-L-TRYPTOPHAN BENZYL ESTER Z-TRP-OBZL N-α-Z-L-tryptophan benzyl ester N-a-Z-L-tryptophanbenzylester Nα-Z-L-tryptophan benzyl ester≥ 99% (HPLC) Z-L-Trp-OBzl N-Benzyloxycarbonyl-L-tryptophan benzyl ester benzyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate L-Tryptophan, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester Nα-Z-L-tryptophan benzyl ester benzyl (2S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)prop... N-cbz-L-tryptophan benzyl ester Benzyl N-[(benzyloxy)carbonyl]-L-tryptophanate Cbz-Trp-Obn Cbz-Trp-OBzl 69876-37-5 C26H24N2O4 Tryptophan [Trp, W] Z-Amino Acids and Derivatives Z-Amino acid series