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Z-TRP-OBZL

Z-TRP-OBZL structure

CAS No.: 69876-37-5

Chemical Name:: Z-TRP-OBZL

Synonyms: Z-TRP-OBZL;Cbz-Trp-OBzl;Z-L-Trp-OBzl;Z-L-TRYPTOPHAN BENZYL ESTER;N-a-Z-L-tryptophanbenzylester;Nα-Z-L-tryptophan benzyl ester;N-α-Z-L-tryptophan benzyl ester;N-cbz-L-tryptophan benzyl ester;N-.ALPHA.-CBZ-L-TRYPTOPHAN BENZYL ESTER;N-Carbobenzyloxy-L-tryptphan benzyl ester

CBNumber:: CB3358438

Molecular Formula:: C26H24N2O4

Molecular Weight:: 428.48

MDL Number:: MFCD00191163

MOL File:: 69876-37-5.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
Nalpha-Cbz-L-tryptophan Benzyl Ester 97+% ee	AS91250	25g	$221
Z-Trp-OBzl ≥98%	411802	5g	$293
Z-Trp-OBzl	V0756	5g	$54
Nα-Z-L-tryptophanbenzylester,99%(HPLC) 99%(HPLC)	06627	25G	$358.4
Z-TRP-OBZL 95.00%	AAA0001790	1G	$560
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Z-TRP-OBZL Properties

Melting point	105-108℃
Boiling point	656.7±55.0 °C(Predicted)
Density	1.266±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
pka	10.93±0.46(Predicted)
form	Powder
color	White to off-white
optical activity	7.70°(C=0.01g/mL, CHCL3, 20°C, 589nm)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Z-TRP-OBZL price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Activate Scientific	AS91250	Nalpha-Cbz-L-tryptophan Benzyl Ester 97+% ee	69876-37-5	25g	$221	2021-12-16	Buy
ChemPep	411802	Z-Trp-OBzl ≥98%	69876-37-5	5g	$293	2021-12-16	Buy
AK Scientific	V0756	Z-Trp-OBzl	69876-37-5	5g	$54	2021-12-16	Buy
Chem-Impex	06627	Nα-Z-L-tryptophanbenzylester,99%(HPLC) 99%(HPLC)	69876-37-5	25G	$358.4	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0001790	Z-TRP-OBZL 95.00%	69876-37-5	1G	$560	2021-12-16	Buy

Product number	Packaging	Price	Buy
AS91250	25g	$221	Buy
411802	5g	$293	Buy
V0756	5g	$54	Buy
06627	25G	$358.4	Buy
AAA0001790	1G	$560	Buy

Z-TRP-OBZL Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Synthesis

100-51-6

7432-21-5

69876-37-5

GENERAL STEPS: To a stirred suspension of (S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoic acid (2.45 g, 7.2 mmol) in 10 mL of anhydrous dichloromethane, 4-dimethylaminopyridine (DMAP, 88 mg, 0.72 mmol) and benzyl alcohol (1.28 g, 11.8 mmol) were added. A 5 mL solution of N,N'-dicyclohexylcarbodiimide (DCC, 1.48 g, 7.2 mmol) in dichloromethane was slowly added at 0 °C. The reaction was carried out at 0 °C with the addition of N,N'-dicyclohexylcarbodiimide (DCC, 1.48 g, 7.2 mmol). The reaction mixture was slowly warmed to room temperature and stirred overnight. The white precipitate was removed by filtration and the solvent was subsequently removed by distillation under reduced pressure to afford the colorless oily product Cbz-L-tryptophan benzyl ester (3 g, 98%). The product had a rotativity of [α]D20 = +50 (c = 1.0, CHCl3, 365 nm). Thin layer chromatography (TLC) showed Rf = 0.29 (ethyl acetate:hexane = 1:2).1H NMR (400 MHz, CDCl3) δ: 8.26 (br, 1H), 7.56 (d, J = 8.0 Hz, 1H), 7.41-7.33 (m, 9H), 7.26-7.20 (m, 3H), 7.12 (t, J = 8.0 Hz , 1H), 6.76 (d, J = 2.0 Hz, 1H), 5.47 (d, J = 8.0 Hz, 1H), 5.18-5.10 (m, 4H), 4.82 (q, J = 8.0 Hz, 1H), 3.34 (d, J = 5.1 Hz, 2H).13C NMR (100 MHz, CDCl3) δ: 171.8, 155.8 , 136.1, 136.0, 135.1, 128.5, 128.4, 128.3, 128.0, 127.5, 127.4, 126.9, 122.9, 122.0, 119.5, 118.5, 111.2, 109.4, 67.1, 66.8, 54.6, 27.8.Fourier transform infrared (FTIR) spectroscopy ( FTIR, pure sample) showed absorption peaks located at 3395, 3343, 1742, 1458, 1377, 721 cm-1. High resolution mass spectrometry (HRMS, ESI) calculated value of C20H20O4N2 [M + H]+ was 429.1814 and measured value was 429.1821.

References

[1] Patent: US2011/269972, 2011, A1. Location in patent: Page/Page column 20

Z-TRP-OBZL Preparation Products And Raw materials

Raw materials

Benzyl alcohol N-Cbz-L-Tryptophan Dichloromethane Dicyclohexylcarbodiimide

Preparation Products

Z-TRP-OBZL Suppliers

Global( 96)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15082	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9629	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
BOC Sciences	58
GL Biochem (Shanghai) Ltd.	58
GL Biochem(Binhai) Ltd.	58
AFINE CHEMICALS LIMITED	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58

View Lastest Price from Z-TRP-OBZL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	Z-TRP-OBZL 69876-37-5	US $1.00 / KG	1KG	99%	1ton	Career Henan Chemical Co
	2019-07-06	Z-TRP-OBZL 69876-37-5	US $1.00 / KG	1KG	99%	20kg	Career Henan Chemical Co

Z-TRP-OBZL
69876-37-5
US $1.00 / KG
99%
Career Henan Chemical Co

Z-TRP-OBZL
69876-37-5
US $1.00 / KG
99%
Career Henan Chemical Co

Z-TRP-OBZL Spectrum

Z-TRP-OBZL(69876-37-5)¹HNMR

69876-37-5(Z-TRP-OBZL)Related Search:

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Z-TRP-ONP Z-TRP(FOR)-OH Z-Trp(For)-OH.DCHA Z-Trp-Lys(Boc)-NH2 tert-butyl N-[(5S)-6-amino-5-[[(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]-6-oxohexyl]carbamate

N-Cbz-O-tert-butyl-L-serine Z-TYR(TBU)-OH Z-LYS-SBZL HCL

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N-.ALPHA.-CBZ-L-TRYPTOPHAN BENZYL ESTER N-Carbobenzyloxy-L-tryptphan benzyl ester (S)-benzyl 2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate Benzyl (S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate N-[(Phenylmethoxy)carbonyl]-L-tryptophan phenylmethyl ester N-ALPHA-CARBOBENZOXY-L-TRYPTOPHAN ALPHA-BENZYL ESTER Z-L-TRYPTOPHAN BENZYL ESTER Z-TRP-OBZL Cbz-Trp-OBzl N-α-Z-L-tryptophan benzyl ester N-a-Z-L-tryptophanbenzylester Nα-Z-L-tryptophan benzyl ester≥ 99% (HPLC) Z-L-Trp-OBzl N-Benzyloxycarbonyl-L-tryptophan benzyl ester benzyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate L-Tryptophan, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester Nα-Z-L-tryptophan benzyl ester benzyl (2S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)prop... N-cbz-L-tryptophan benzyl ester Benzyl N-[(benzyloxy)carbonyl]-L-tryptophanate 69876-37-5 C26H24N2O4 Tryptophan [Trp, W] Z-Amino Acids and Derivatives Z-Amino acid series