METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
- CAS No.
- 37619-24-2
- Chemical Name:
- METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
- Synonyms
- RARECHEM AL BF 0084;2-Methoxycarbonyl-1-methylpyrrole;Methyl 1-Methyl-2-pyrrolecarboxylate;methyl N-methylpyrrole-2-carboxylate;Methyl-4-methylpyrrole-2-carboxylate;METHYL 1-METHYLPYRROLE-2-CARBOXYLATE;Methyl1-methylpyrrole-2-carboxylate,98%;METHYL 1-METHYL-1H-PYRROLE-2-CARBOXYLATE;1-METHYLPYRROLE-2-CARBOXYLIC ACID METHYL ESTER;1-Methyl-1H-pyrrole-2-carboxylic acid methyl ester
- CBNumber:
- CB3407697
- Molecular Formula:
- C7H9NO2
- Molecular Weight:
- 139.15
- MDL Number:
- MFCD00052747
- MOL File:
- 37619-24-2.mol
| Melting point | 80 °C (sublm)(Press: 0.2 Torr) |
|---|---|
| Boiling point | 96-98°C 15mm |
| Density | 1.07±0.1 g/cm3(Predicted) |
| refractive index | 1.5220 |
| Flash point | 96-98°C/15mm |
| storage temp. | Sealed in dry,Room Temperature |
| pka | -7.04±0.70(Predicted) |
| Appearance | Light yellow to brown Liquid |
| Water Solubility | Slightly soluble in water. |
| BRN | 116477 |
| CAS DataBase Reference | 37619-24-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
METHYL 1-METHYLPYRROLE-2-CARBOXYLATE price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B451520 | Methyl1-Methylpyrrole-2-carboxylate | 37619-24-2 | 100mg | $75 | 2021-12-16 | Buy |
| Matrix Scientific | 045456 | Methyl 1-methyl-1H-pyrrole-2-carboxylate >95% | 37619-24-2 | 5g | $59 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H23-1-4S | Methyl 1-methyl-1H-pyrrole-2-carboxylate | 37619-24-2 | 1g | $96 | 2021-12-16 | Buy |
| Matrix Scientific | 045456 | Methyl 1-methyl-1H-pyrrole-2-carboxylate >95% | 37619-24-2 | 500mg | $10 | 2021-12-16 | Buy |
| Matrix Scientific | 045456 | Methyl 1-methyl-1H-pyrrole-2-carboxylate >95% | 37619-24-2 | 1g | $14 | 2021-12-16 | Buy |
METHYL 1-METHYLPYRROLE-2-CARBOXYLATE Chemical Properties,Uses,Production
Uses
Methyl 1-methylpyrrole-2-carboxylate is used as chemical and organic Intermediates.
Synthesis
1193-62-0
74-88-4
37619-24-2
Methyl-1H-pyrrole-2-carboxylate (10 g, 79.9 mmol) was dissolved in anhydrous THF (200 mL) at 0 °C and NaH (3.52 g, 60% w/w, 87.9 mmol) was slowly added. The reaction mixture was stirred at 20 °C for 30 min before CH3I (13.62 g, 95.9 mmol) was added dropwise. The reaction was continued to be stirred at 20 °C for 17 hours. After completion of the reaction, the reaction was quenched by slowly pouring the mixture into aqueous NH4Cl (200 mL). The aqueous phase was extracted with EtOAc (200 mL x 2), the organic layers were combined and washed with brine (150 mL), dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: EtOAc/petroleum ether=1/20) to afford methyl 1-methyl-1H-pyrrole-2-carboxylate (9.88 g, 71 mmol, 89% yield) as a yellow oil. Mass spectrum (EI+, m/z): 140.1 [M+H]+.
References
[1] Organic Letters, 2015, vol. 17, # 11, p. 2652 - 2655
[2] Patent: WO2018/89493, 2018, A1. Location in patent: Paragraph 00214
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 11, p. 3219 - 3223
METHYL 1-METHYLPYRROLE-2-CARBOXYLATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8285 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
View Lastest Price from METHYL 1-METHYLPYRROLE-2-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-12-26 | METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
37619-24-2
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
37619-24-2
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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