CYN 154806
- CAS No.
- 183658-72-2
- Chemical Name:
- CYN 154806
- Synonyms
- CYN 154806;CYANAMID 154806;CYN154806 ，P1236;CYN 154806; CYN154806;M.W. 1197.35 C56H68N12O14S2;CYN 154806 TRIFLUOROACETATE SALT;CYANAMID 154806 trifluoroacetate salt;AC-(4-NITRO)PHE-D-CYS-TYR-D-TRP-LYS-THR-CYS-D-TYR-NH2;Ac-4-NO2-Phe-c(D-Cys-Tyr-D-Trp-Lys-Thr-Cys)-D-Tyr-NH2;CYN 154806, selective somatostatin receptor 2 (sst2) antagonist
- CBNumber:
- CB3428029
- Molecular Formula:
- C56H68N12O14S2
- Molecular Weight:
- 1197.34
- MDL Number:
- MFCD06411598
- MOL File:
- 183658-72-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 1656.2±65.0 °C(Predicted) |
|---|---|
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility |
DMF: 25 mg/ml DMSO: 10 mg/ml Ethanol: 25 mg/ml |
| pka | 9.87±0.15(Predicted) |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble to 1 mg/ml in water |
| Sequence | Ac-{L-4-NO2-Phe}{D-CYS}-Tyr-{D-TRP}-Lys-Thr-Cys{D-TYR}-NH2 (Disulfidebridge:Cys2-Cys7) |
| InChIKey | FYVCFCQFOBEWIO-GVGJFGMUSA-N |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
CYN 154806 price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C2490 | CYN 154806 trifluoroacetate salt ≥98% (HPLC) | 183658-72-2 | 500μg | $243 | 2026-04-30 | Buy |
| Cayman Chemical | 37343 | CYN 154806 (trifluoroacetate salt) ≥90% | 500μg | $112 | 2026-04-30 | Buy | |
| Cayman Chemical | 37343 | CYN 154806 (trifluoroacetate salt) ≥90% | 1mg | $212 | 2026-04-30 | Buy | |
| Cayman Chemical | 37343 | CYN 154806 (trifluoroacetate salt) ≥90% | 5mg | $556 | 2026-04-30 | Buy | |
| Usbiological | 255075 | CYN 154806 Asreported | 183658-72-2 | 1mg | $531 | 2026-06-03 | Buy |
CYN 154806 Chemical Properties, Uses, Production
Description
CYN 154806 is a cyclic peptide somatostatin receptor 2 (SST2) antagonist (IC50 = 2.62 nM).1 It is selective for SST2 over SST1, SST3, SST4, and SST5 (IC50s = 3,890, 851, 1,737, and 331 nM, respectively). CYN 154806 inhibits SST-induced increases in extracellular acidification (EAR) in CHO-K1 cells expressing recombinant human SST2 (pKB = 7.92) and [35S]GTPγS binding in CHO-K1 cell membranes expressing recombinant human SST2 (pKB = 7.81).WARNING This product is not for human or veterinary use.
Biochem/physiol Actions
Potent and selective sst2 somatostatin receptor antagonist.
storage
Store at -20°C
References
[1] W FENIUK. Selective somatostatin sst2 receptor blockade with the novel cyclic octapeptide, CYN-154806[J]. Neuropharmacology, 2000, 39 8: Pages 1443-1450. DOI: 10.1016/s0028-3908(00)00035-6
CYN 154806 Preparation Products And Raw materials
Raw materials
Preparation Products
CYN 154806 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
