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ChemicalBook >> CAS DataBase List >>cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Structure
cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole structure
CAS No.
370879-56-4
Chemical Name:
cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole
Synonyms
cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole;cis-tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate;(3aR,6aS)-tert-butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate;tert-butyl (3aR,6aS)-2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate;Pyrrolo[3,4-c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-(phenylmethyl)-, 1,1-dimethylethyl ester, (3aR,6aS)-rel-
CBNumber:
CB3449709
Molecular Formula:
C18H26N2O2
Molecular Weight:
302.41
MDL Number:
MFCD04116223
MOL File:
370879-56-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:03
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cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Properties

Boiling point 393.4±35.0 °C(Predicted)
Density 1.117±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 8.97±0.20(Predicted)
Appearance Colorless to light yellow Liquid

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00C7KQ CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE 97% 370879-56-4 100mg $38 2026-05-28 Buy
aablocks AA00C7KQ CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE 97% 370879-56-4 250mg $87 2026-05-28 Buy
aablocks AA00C7KQ CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE 97% 370879-56-4 1g $344 2026-05-28 Buy
ACHEMBLOCK AD262473 cis-tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate 95% 370879-56-4 250MG $150 2026-05-27 Buy
ACHEMBLOCK AD262473 cis-tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate 95% 370879-56-4 1G $600 2026-05-27 Buy
Product number Packaging Price Buy
AA00C7KQ 100mg $38 Buy
AA00C7KQ 250mg $87 Buy
AA00C7KQ 1g $344 Buy
AD262473 250MG $150 Buy
AD262473 1G $600 Buy

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Chemical Properties, Uses, Production

Synthesis

CIS-2-BENZYLOCTAHYDROPYRROLO[3,4-C]PYRROLE

172739-04-7

Di-tert-butyl dicarbonate

24424-99-5

CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE

370879-56-4

To a solution of (3aR,6aS)-2-benzyl octahydropyrrolo[3,4-c]pyrrole (10 g, 49.5 mmol) in tetrahydrofuran (THF, 100 mL) was sequentially added N,N-diisopropylethylamine (DIPEA, 12.8 g, 99 mmol) and di-tert-butyl dicarbonate (Boc2O, 10.8 g, 49.5 mmol). The reaction mixture was stirred at room temperature for 5 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and washed sequentially with water, saturated sodium bicarbonate (NaHCO3) solution and saturated saline. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford tert-butyl (3aR,6aS)-5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate as a yellow oil (12 g, 80%).

References

[1] Patent: WO2015/120049, 2015, A1. Location in patent: Page/Page column 139
[2] Patent: WO2016/191172, 2016, A1. Location in patent: Page/Page column 85
[3] Patent: US2002/19388, 2002, A1
[4] Patent: US2009/281118, 2009, A1. Location in patent: Page/Page column 10
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 14, p. 4126 - 4141

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole synthesis

172739-04-7
24424-99-5
370879-56-4
Synthesis of cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole from cis-2-Benzyloctahydropyrrolo[3,4-c]pyrrole and Di-tert-butyl dicarbonate

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Preparation Products And Raw materials

Raw materials

cis-2-Benzyloctahydropyrrolo[3,4-c]pyrrole Tetrahydrofuran Di-tert-butyl dicarbonate N,N-Diisopropylethylamine

Preparation Products

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Suppliers

Global Suppliers ( 28)
Supplier Tel Email Country ProdList Advantage
Shanghai Sheepchem Co., Ltd. +86 (21) 6715-7650 sheepchem@163.com China 993 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Zhejiang Lianshuo Biotechnology Co., Ltd. 18616526224 lianshuo@vip.126.com China 9605 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49897 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 43066 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39662 58
Suzhou Victorypharm Co.,Ltd. 512-68242903 13916956214 sales@victory-pharm.com China 1587 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39319 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50460 58
Supplier Advantage
Shanghai Sheepchem Co., Ltd. 60
Shanghai HuanChuan Industry Co.,Ltd. 50
Amadis Chemical Company Limited 58
Zhejiang Lianshuo Biotechnology Co., Ltd. 58
CONIER CHEM AND PHARMA LIMITED 58
Energy Chemical 58
Bide Pharmatech Ltd. 58
Suzhou Victorypharm Co.,Ltd. 58
Shanghai Haohong Scientific Co., Ltd. 58
Beijing Solarbio Science & Tecnology Co., Ltd. 58

cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Spectrum

CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE(370879-56-4)1HNMR

370879-56-4 (cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole) Related Search:

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cis-tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (3aR,6aS)-tert-butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate tert-butyl (3aR,6aS)-2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate Pyrrolo[3,4-c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-(phenylmethyl)-, 1,1-dimethylethyl ester, (3aR,6aS)-rel- cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole 370879-56-4 C18H26N2O2 pharmacetical