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1-(4-Hydroxyphenyl)-1-butanone

CAS No.
1009-11-6
Chemical Name:
1-(4-Hydroxyphenyl)-1-butanone
Synonyms
1-(4-HYDROXYPHENYL)BUTAN-1-ONE;4-HYDROXYBUTANOPHENONE;P-HYDROXYBUTYROPHENONE;PROPYL 4-H;4-Butyrylphenol;p-Butyrylphenol;4-Butanoylphenol;p-Hydroxybutanone;1-(4-Hydroxyphenyl)-;4'-Hydroxybutyrophenone
CBNumber:
CB3469013
Molecular Formula:
C10H12O2
Molecular Weight:
164.2
MDL Number:
MFCD00020173
MOL File:
1009-11-6.mol
MSDS File:
SDS
Last updated:2026-05-28 06:33:06

1-(4-Hydroxyphenyl)-1-butanone Properties

Melting point 93°C
Boiling point 174 °C / 40mmHg
Density 1.0435 g/cm3(Temp: 24 °C)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
pka 8.05±0.15(Predicted)
form powder to crystal
color White to Yellow to Orange
InChI InChI=1S/C10H12O2/c1-2-3-10(12)8-4-6-9(11)7-5-8/h4-7,11H,2-3H2,1H3
InChIKey GFBLPULLSAPXDC-UHFFFAOYSA-N
SMILES C(C1=CC=C(O)C=C1)(=O)CCC
CAS DataBase Reference 1009-11-6(CAS DataBase Reference)
NIST Chemistry Reference 1-(4-Hydroxyphenyl)-1-butanone(1009-11-6)
EPA Substance Registry System 1-Butanone, 1-(4-hydroxyphenyl)- (1009-11-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  2914500090
NFPA 704
0
1 0

1-(4-Hydroxyphenyl)-1-butanone price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical H0903 4'-Hydroxybutyrophenone >98.0%(GC) 1009-11-6 25g $86 2026-04-30 Buy
Usbiological 279698 4-Hydroxybutyrophenone Asreported 1009-11-6 5g $345 2026-06-03 Buy
Usbiological 279698 4-Hydroxybutyrophenone Asreported 1009-11-6 10g $475 2026-06-03 Buy
Usbiological 279698 4-Hydroxybutyrophenone Asreported 1009-11-6 25g $639 2026-06-03 Buy
Usbiological 279698 4-Hydroxybutyrophenone Asreported 1009-11-6 50g $859 2026-06-03 Buy
Product number Packaging Price Buy
H0903 25g $86 Buy
279698 5g $345 Buy
279698 10g $475 Buy
279698 25g $639 Buy
279698 50g $859 Buy

1-(4-Hydroxyphenyl)-1-butanone Chemical Properties, Uses, Production

Uses

4'-HYDROXYBUTYROPHENONE is a useful research chemical.

Synthesis

Butyryl chloride

141-75-3

Phenol

108-95-2

1-(4-Hydroxyphenyl)-1-butanone

1009-11-6

General method: phenol (0.28 mmol) and n-butyryl chloride (0.28 mmol) were dissolved in trifluoromethanesulfonic acid (TfOH, 3 mL) at 0°C. The reaction mixture was gradually warmed up to room temperature and the reaction was carried out for the time shown in Table 2. Upon completion of the reaction, the mixture was poured into a mixture of cold water and ethyl acetate. The organic layer was separated and washed sequentially with 1 M hydrochloric acid, saturated sodium bicarbonate solution and saturated sodium chloride solution. The organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate concentrated. The residue was purified by silica gel column chromatography to give 4'-hydroxybutyrophenone. The spectral data of all the products were in agreement with those reported in the literature.

References

[1] Tetrahedron, 2011, vol. 67, # 3, p. 641 - 649
[2] Chemische Berichte, 1985, vol. 118, # 8, p. 3332 - 3349
[3] Journal fuer Praktische Chemie (Leipzig), 1989, vol. 331, # 4, p. 617 - 630
[4] Journal of the Chemical Society, 1889, vol. 55, p. 551
[5] Journal of the Chemical Society, 1896, vol. 69, p. 1176

141-75-3
108-95-2
1009-11-6
Synthesis of 1-(4-Hydroxyphenyl)-1-butanone from Butyryl chloride and Phenol

1-(4-Hydroxyphenyl)-1-butanone Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 246)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6740 52
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57

View Latest Price from 1-(4-Hydroxyphenyl)-1-butanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-Hydroxyphenyl)-1-butanone pictures 2026-03-20 1-(4-Hydroxyphenyl)-1-butanone
1009-11-6
1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
1-(4-Hydroxyphenyl)-1-butanone pictures 2025-12-24 1-(4-Hydroxyphenyl)-1-butanone
1009-11-6
1KG 99.0% 1000KG Shaanxi Dideu Medichem Co. Ltd
4-Hydroxybutyrophenone pictures 2025-06-20 4-Hydroxybutyrophenone
1009-11-6
1kg 0.99 100kg Hebei Yanxi Chemical Co., Ltd.
4-HYDROXYPHENYL PROPYL KETONE 1-(4-HYDROXYPHENYL)BUTANONE 1-(4-HYDROXYPHENYL)-1-BUTANONE 4-Butanoylphenol 4-Butyrylphenol PROPYL 4-HYDROXYPHENYL KETONE 1-(4-hydroxyphenyl)-1-butanon 1-Butanone, 1-(4-hydroxyphenyl)- 1-(4-hydroxyphenyl)-2-butanone PROPYL 4-H Butyrophenone, 4'-hydroxy- p-Butyrylphenol 4-HYDROXYPHENYL-1-BUTANONE 1-(4-Hydroxyphenyl)- 4-hydroxyphenyl butanone 4'-Hydroxybutyrophenone> 99% purity 1-(4-Hydroxyphenyl)-1-butanone high quality 1-(4-Hydroxyphenyl)-1-butanone 1-(4-Hydroxyphenyl)-1-butan 4-Hydroxybutyrophenone Powder 4'-Hydroxybutyrophenone p-Hydroxybutanone 4-HYDROXYBUTANOPHENONE 1-(4-HYDROXYPHENYL)BUTAN-1-ONE P-HYDROXYBUTYROPHENONE 1009-11-6 KETONE 1009-11-6