5-Nitro-2-furoyl chloride
- CAS No.
- 25084-14-4
- Chemical Name:
- 5-Nitro-2-furoyl chloride
- Synonyms
- 5-NITROFURAN-2-CARBONYL CHLORIDE;Ai3-23633;Einecs 246-607-6;5-nitrofuroyl chloride;5-Nitro-2-furoyl chloride;2-Furoyl chloride, 5-nitro-;5-Nitro-2-furancarbonyl chloride;2-Furancarbonyl chloride, 5-nitro-;5-nitrofuran-2-carboxylic chloride;N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide
- CBNumber:
- CB3470912
- Molecular Formula:
- C5H2ClNO4
- Molecular Weight:
- 175.53
- MDL Number:
- MFCD00039564
- MOL File:
- 25084-14-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 34-41 °C |
|---|---|
| Boiling point | 137-140°C 15mm |
| Density | 1.588±0.06 g/cm3(Predicted) |
| Flash point | 137-140°C/15mm |
| form | solid |
| Sensitive | Moisture Sensitive |
| BRN | 139693 |
| InChI | 1S/C5H2ClNO4/c6-5(8)3-1-2-4(11-3)7(9)10/h1-2H |
| InChIKey | OLEFNFXYGGTROA-UHFFFAOYSA-N |
| SMILES | [O-][N+](=O)c1ccc(o1)C(Cl)=O |
| CAS DataBase Reference | 25084-14-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 3261 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2932190090 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Corr. 1B |
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| NFPA 704 |
|
5-Nitro-2-furoyl chloride price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 683752 | 5-Nitro-2-furoyl chloride 95% | 25084-14-4 | 5g | $246 | 2026-04-30 | Buy |
| Sigma-Aldrich | 683752 | 5-Nitro-2-furoyl chloride 95% | 25084-14-4 | 25g | $908 | 2023-06-20 | Buy |
| Apolloscientific | OR27281 | 5-Nitrofuran-2-carbonyl chloride 95% | 25084-14-4 | 5g | $192 | 2026-06-04 | Buy |
| aablocks | AA002QDA | 5-Nitrofuran-2-carbonyl chloride ≥95% | 25084-14-4 | 5g | $248 | 2026-05-28 | Buy |
| aablocks | AA002QDA | 5-Nitrofuran-2-carbonyl chloride ≥95% | 25084-14-4 | 25g | $866 | 2026-05-28 | Buy |
5-Nitro-2-furoyl chloride Chemical Properties, Uses, Production
Description
5-Nitrofuroyl chloride is a furan chain bound to an acyl and a nitro group. Nitrofuran derivatives have been used as antibiotic and antimicrobial drugs but the acyl group bound to furan (furoyl chloride) is an intermediate for the synthesis of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride has been used as a reagent for the synthesis of some compounds with antibacterial properties and other chemicals.
Uses
5-Nitrofuroyl chloride has been used in the synthesis of certain ureides of furanmonocarboxylic acid and in the synthesis of two salts of the mesoionic compound with an influence on the effectiveness of norfloxacin, tetracycline, and erythromycin. There is a study on the antibacterial effects of some 5-nirtofuroyl derivatives but not on 5-nitrofuroyl chloride. There are no reports on its commercial use.
Uses
5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents.
Environmental Fate
5-Nitrofuroyl chloride is a colorless crystal with molecular weight of 175.53 g mol-1. It is stable under normal temperature and pressure on the basis of its melting point (38–14℃). There are no available data on its solubility in water. The bioaccumulation factor (BCF) for this compound is 4.29 at pH 7.4, which indicates low accumulation in aquatic organisms. The soil adsorption coefficient normalized to the content of organic carbon (Koc value) is 98.92 at pH 7.4, which indicates high mobility in soil.
5-Nitro-2-furoyl chloride Preparation Products And Raw materials
5-Nitro-2-furoyl chloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9985 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2886750 13927877953 | 3005811397@qq.com | China | 13282 | 58 |
