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5-NITRO-2-FUROYL CHLORIDE

CAS No.
25084-14-4
Chemical Name:
5-NITRO-2-FUROYL CHLORIDE
Synonyms
5-NITROFURAN-2-CARBONYL CHLORIDE;Ai3-23633;Einecs 246-607-6;5-nitrofuroyl chloride;5-NITRO-2-FUROYL CHLORIDE;2-Furoyl chloride, 5-nitro-;5-Nitro-2-furancarbonyl chloride;2-Furancarbonyl chloride, 5-nitro-;5-nitrofuran-2-carboxylic chloride;N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide
CBNumber:
CB3470912
Molecular Formula:
C5H2ClNO4
Molecular Weight:
175.53
MDL Number:
MFCD00039564
MOL File:
25084-14-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:33:08
Product description Number Pack Size Price
5-Nitro-2-furoyl chloride 95% 683752 5g $246
5-Nitro-2-furoyl chloride 95% 683752 25g $908
5-Nitrofuran-2-carbonyl chloride 95% OR27281 5g $192
5-Nitrofuran-2-carbonyl chloride ≥95% AA002QDA 5g $248
5-Nitrofuran-2-carbonyl chloride ≥95% AA002QDA 25g $866

5-NITRO-2-FUROYL CHLORIDE Properties

Melting point 34-41 °C
Boiling point 137-140°C 15mm
Density 1.588±0.06 g/cm3(Predicted)
Flash point 137-140°C/15mm
form solid
Sensitive Moisture Sensitive
BRN 139693
InChI 1S/C5H2ClNO4/c6-5(8)3-1-2-4(11-3)7(9)10/h1-2H
InChIKey OLEFNFXYGGTROA-UHFFFAOYSA-N
SMILES [O-][N+](=O)c1ccc(o1)C(Cl)=O
CAS DataBase Reference 25084-14-4(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  3261
WGK Germany  3
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  2932190090
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Skin Corr. 1B
NFPA 704
1
3 0

5-NITRO-2-FUROYL CHLORIDE price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 683752 5-Nitro-2-furoyl chloride 95% 25084-14-4 5g $246 2026-04-30 Buy
Sigma-Aldrich 683752 5-Nitro-2-furoyl chloride 95% 25084-14-4 25g $908 2023-06-20 Buy
Apolloscientific OR27281 5-Nitrofuran-2-carbonyl chloride 95% 25084-14-4 5g $192 2026-06-04 Buy
aablocks AA002QDA 5-Nitrofuran-2-carbonyl chloride ≥95% 25084-14-4 5g $248 2026-05-28 Buy
aablocks AA002QDA 5-Nitrofuran-2-carbonyl chloride ≥95% 25084-14-4 25g $866 2026-05-28 Buy
Product number Packaging Price Buy
683752 5g $246 Buy
683752 25g $908 Buy
OR27281 5g $192 Buy
AA002QDA 5g $248 Buy
AA002QDA 25g $866 Buy

5-NITRO-2-FUROYL CHLORIDE Chemical Properties,Uses,Production

Description

5-Nitrofuroyl chloride is a furan chain bound to an acyl and a nitro group. Nitrofuran derivatives have been used as antibiotic and antimicrobial drugs but the acyl group bound to furan (furoyl chloride) is an intermediate for the synthesis of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride has been used as a reagent for the synthesis of some compounds with antibacterial properties and other chemicals.

Uses

5-Nitrofuroyl chloride has been used in the synthesis of certain ureides of furanmonocarboxylic acid and in the synthesis of two salts of the mesoionic compound with an influence on the effectiveness of norfloxacin, tetracycline, and erythromycin. There is a study on the antibacterial effects of some 5-nirtofuroyl derivatives but not on 5-nitrofuroyl chloride. There are no reports on its commercial use.

Uses

5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents.

Environmental Fate

5-Nitrofuroyl chloride is a colorless crystal with molecular weight of 175.53 g mol-1. It is stable under normal temperature and pressure on the basis of its melting point (38–14℃). There are no available data on its solubility in water. The bioaccumulation factor (BCF) for this compound is 4.29 at pH 7.4, which indicates low accumulation in aquatic organisms. The soil adsorption coefficient normalized to the content of organic carbon (Koc value) is 98.92 at pH 7.4, which indicates high mobility in soil.

645-12-5
25084-14-4
Synthesis of 5-NITRO-2-FUROYL CHLORIDE from 5-Nitro-2-furoic acid

5-NITRO-2-FUROYL CHLORIDE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12373 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
+8618950047208 ellena@amitychem.com China 43414 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40228 62
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15838 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30123 84
5-NITRO-2-FUROYL CHLORIDE 2-Furancarbonyl chloride, 5-nitro- 2-Furoyl chloride, 5-nitro- 5-nitrofuroyl chloride Ai3-23633 Einecs 246-607-6 5-Nitro-2-furancarbonyl chloride 5-Nitro-2-furoyl chloride, predominantly trans, 97% 5-nitrofuran-2-carboxylic chloride N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide 5-NITROFURAN-2-CARBONYL CHLORIDE 25084-14-4 C5H2ClNO4 ACID CHLORIDE Building Blocks C4 to C7 Chemical Synthesis Furans Heterocyclic Building Blocks