(1R,2R)-2-PCCA(hydrochloride)
- CAS No.
- 1609563-71-4
- Chemical Name:
- (1R,2R)-2-PCCA(hydrochloride)
- Synonyms
- (1R,2R)-2-PCCA HCl;(1R,2R)-2-PCCA 2HCl;2R)-2-PCCA(hydrochloride);(1R,2R)-2-PCCA(hydrochloride);(1R,2R)-2-PCCA hydrochloride, 10 mM in DMSO;(1R,2R)2PCCA hydrochloride,(1R,2R) 2 PCCA hydrochloride;(1R,2R)-N-((2S,3S)-2-Amino-3-methylpentyl)-N-(4'-propyl-[1,1'-biphenyl]-4-yl)-2-(pyridin-2-yl)cyclopropane-1-carboxamide dihydrochloride;(1R,2R)-N-((2S,3S)-2-Amino-3-methylpentyl)-N-(4'-propyl-[1,1'-biphenyl]-4-yl)-2-(pyridin-2-yl)cyclopropane-1-carboxamide dihydrochloride
- CBNumber:
- CB34796629
- Molecular Formula:
- C30H38ClN3O
- Molecular Weight:
- 492.1
- MDL Number:
- MOL File:
- 1609563-71-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
(1R,2R)-2-PCCA(hydrochloride) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0044244 | (1R,2R)-2-PCCA hydrochloride 98.08% | 1609563-71-4 | 1mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-0044244 | (1R,2R)-2-PCCA hydrochloride 98.08% | 1609563-71-4 | 5mg | $195 | 2026-06-04 | Buy |
| ChemScene | CS-0044244 | (1R,2R)-2-PCCA hydrochloride 98.08% | 1609563-71-4 | 10mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0044244 | (1R,2R)-2-PCCA hydrochloride 98.08% | 1609563-71-4 | 25mg | $780 | 2026-06-04 | Buy |
| ChemScene | CS-0044244 | (1R,2R)-2-PCCA hydrochloride 98.08% | 1609563-71-4 | 50mg | $1029 | 2026-06-04 | Buy |
(1R,2R)-2-PCCA(hydrochloride) Chemical Properties, Uses, Production
Uses
(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay, and 603 nM in cell assay.
References
[1] Bi, Yingzhi, et al. Modulators of G Protein-Coupled Receptor 88. US 20110251204 A1.
[2] Jin C, et al. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor. ACS Chem Neurosci. 2014 Jul 16;5(7):576-87. DOI:10.1021/cn500082p
[3] Jin C, et al. Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies. ACS Chem Neurosci. 2016 Oct 19;7(10):1418-1432. DOI:10.1021/acschemneuro.6b00182
(1R,2R)-2-PCCA(hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
(1R,2R)-2-PCCA(hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2377 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Beijing Boorsen Biotechnology Co., Ltd | 400-901-9800 18611424007 | cis@bioss.com.cn | China | 9185 | 58 |
