Emodin-3-methyl ether
- CAS No.
- 521-61-9
- Chemical Name:
- Emodin-3-methyl ether
- Synonyms
- PHYSCION;PHYSCIONE;RHEOCHRYSIDIN;parietin;MethyleModin;Rheochrysidin (Physcion);Emodin-3-methyl ether 521-61-9;1,8-dihydroxy-3-Methoxy-6-Methylanthracene-9,10-dione;Physcion-RM;Physcic acid
- CBNumber:
- CB3487525
- Molecular Formula:
- C16H12O5
- Molecular Weight:
- 284.26
- MDL Number:
- MFCD00017374
- MOL File:
- 521-61-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Physcion analytical standard | 93893 | 10mg | $334 |
| Physcion ≥98.0% (TLC) | 17797 | 100mg | $730 |
| Physcion | P2931 | 100MG | $189 |
| Physcion ≥98% | 19863 | 5mg | $36 |
| Physcion ≥98% | 19863 | 10mg | $63 |
| More product size | |||
| Melting point | 196-206°C |
|---|---|
| Boiling point | 560.5±50.0 °C(Predicted) |
| Density | 1.448±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly) |
| pka | 6.23±0.20(Predicted) |
| form | Solid |
| color | Yellow to Dark Yellow to Dark Orange |
| BRN | 6770499 |
| Stability | Hygroscopic |
| Major Application | food and beverages |
| InChI | InChI=1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3 |
| InChIKey | FFWOKTFYGVYKIR-UHFFFAOYSA-N |
| SMILES | C1(O)=C2C(C(=O)C3=C(C2=O)C(O)=CC(C)=C3)=CC(OC)=C1 |
| LogP | 5.078 (est) |
| CAS DataBase Reference | 521-61-9(CAS DataBase Reference) |
| FDA UNII | H6PT94IV61 |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CB6720000 | |||||||||
| F | 10 | |||||||||
| HS Code | 29146990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
Emodin-3-methyl ether price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93893 | Physcion analytical standard | 521-61-9 | 10mg | $334 | 2026-04-30 | Buy |
| Sigma-Aldrich | 17797 | Physcion ≥98.0% (TLC) | 521-61-9 | 100mg | $730 | 2026-04-30 | Buy |
| TCI Chemical | P2931 | Physcion | 521-61-9 | 100MG | $189 | 2026-04-30 | Buy |
| Cayman Chemical | 19863 | Physcion ≥98% | 521-61-9 | 5mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 19863 | Physcion ≥98% | 521-61-9 | 10mg | $63 | 2026-04-30 | Buy |
Emodin-3-methyl ether Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
antibacterial, cathartic
Uses
A natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew.
Definition
ChEBI: A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6.
Biological Activity
Anthraquinone-derivative found in medicinal herbs.
in vivo
Physcion (20 or 40 mg/kg, p.o., once daily for 7 days) exerts neuroprotective effects by inhibiting the TLR4/NF-κB signaling pathway in an ischemia-reperfusion-induced SD rat model[3]. Physcion (4 or 9 mg/kg, p.o., once daily for 6 days) effectively alleviates infection symptoms caused by Chlamydia psittaci 6 BCE in SPF chickens[4].
| Animal Model: | Ischemia-reperfusion (I/R)-induced focal cerebral ischemia model in SD rats[3] |
| Dosage: | 20 or 40 mg/kg |
| Administration: | Oral gavage (p.o.), once daily for 7 days |
| Result: | Significantly reduced the brain water content and the NSS (Neurological Severity Score) in I/R rats, compared to I/R group. Obviously decreased areas of infarction compared to I/R group. |
| Animal Model: | SPF chickens (21 days old) infected intra-laryngeally with Chlamydia psittaci 6 BCE[4] |
| Dosage: | 4 or 9 mg/kg |
| Administration: | Oral gavage (p.o.), once daily for 6 days |
| Result: | Dose-dependently alleviated respiratory distress, air sac and lung lesions, and bacterial load in the spleen in infected chickens. |
IC 50
TLR4
Emodin-3-methyl ether Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 | Jerry@xhobio.com | China | 906 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 954 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Shaanxi Yikanglong Biotechnology Co., Ltd. | 17791478691 | yklbiotech@163.com | CHINA | 296 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 1169 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | 029-84385017; +8613259417953 | sales@pioneerbiotech.com | China | 1287 | 58 |
View Lastest Price from Emodin-3-methyl ether manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-10 | Physcion
521-61-9
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-07-07 | Emodin-3-methyl ether
521-61-9
|
20MG | ≥98% HPLC | 100kg | Changsha Staherb Natural Ingredients Co., Ltd. | ||
 |
2026-06-01 | Physcion
521-61-9
|
$43.00-129.00 | 97.35% | 10g | TargetMol Chemicals Inc. |
-
- Physcion
521-61-9
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Emodin-3-methyl ether
521-61-9
- $0.00
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Physcion
521-61-9
- $43.00-129.00
- 97.35%
- TargetMol Chemicals Inc.
