2-(Diethylamino)ethyl methacrylate
- CAS No.
- 105-16-8
- Chemical Name:
- 2-(Diethylamino)ethyl methacrylate
- Synonyms
- DEAEMA;N,N-DIETHYLAMINOETHYL METHACRYLATE;DIETHYLAMINOETHYL METHACRYLATE;2-(n,n-diethylamino)ethyl;2-(Diethylamino)ethanol methacrylate;2-(N,N-DIETHYLAMINO)ETHYL METHACRYLATE;daktoseb;Daktose B;diethylaminoethylmet;CHLUMICRYI DEAM Monomer
- CBNumber:
- CB3495322
- Molecular Formula:
- C10H19NO2
- Molecular Weight:
- 185.26
- MDL Number:
- MFCD00038314
- MOL File:
- 105-16-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -60°C |
|---|---|
| Boiling point | 80 °C10 mm Hg(lit.) |
| Density | 0.922 g/mL at 25 °C(lit.) |
| vapor pressure | 11Pa at 20℃ |
| refractive index |
n |
| Flash point | 170 °F |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 9.18±0.25(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Decomposition | 176-178 ºC |
| Cosmetics Ingredients Functions | NAIL CONDITIONING |
| InChI | 1S/C10H19NO2/c1-5-11(6-2)7-8-13-10(12)9(3)4/h3,5-8H2,1-2,4H3 |
| InChIKey | SJIXRGNQPBQWMK-UHFFFAOYSA-N |
| SMILES | CCN(CC)CCOC(=O)C(C)=C |
| LogP | 2.560 (est) |
| CAS DataBase Reference | 105-16-8(CAS DataBase Reference) |
| FDA UNII | N5SI2E7HOU |
| NIST Chemistry Reference | Diethylaminoethyl methacrylate(105-16-8) |
| EPA Substance Registry System | 2-(Diethylamino)ethyl methacrylate (105-16-8) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H317-H319-H332 | |||||||||
| Precautionary statements | P261-P264-P280-P302+P352-P304+P340+P312-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20-36/38-43 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | OZ4150000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29224999 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Inhalation Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
|||||||||
| Hazardous Substances Data | 105-16-8(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LC50,inhalation,12100mg/m3/2H (12100mg/m3),"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 51, 1982. | |||||||||
| REACH Registrations | Active | |||||||||
| Excepted Quantities | Non-Hazardous | |||||||||
| NFPA 704 |
|
2-(Diethylamino)ethyl methacrylate price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 408980 | 2-(Diethylamino)ethyl methacrylate contains 1500 ppm MEHQ as inhibitor, 99% | 105-16-8 | 250ml | $63.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 408980 | 2-(Diethylamino)ethyl methacrylate contains 1500 ppm MEHQ as inhibitor, 99% | 105-16-8 | 1l | $175 | 2026-04-30 | Buy |
| TCI Chemical | M0562 | 2-(Diethylamino)ethyl Methacrylate (stabilized with MEHQ) >98.5%(GC) | 105-16-8 | 25mL | $19 | 2026-04-30 | Buy |
| TCI Chemical | M0562 | 2-(Diethylamino)ethyl Methacrylate (stabilized with MEHQ) >98.5%(GC) | 105-16-8 | 500mL | $68 | 2026-04-30 | Buy |
| Biosynth | AAA10516 | 2-(Diethylamino)ethyl Methacrylate | 105-16-8 | 5000g | $2000 | 2026-06-04 | Buy |
2-(Diethylamino)ethyl methacrylate Chemical Properties, Uses, Production
Chemical Properties
Colorless liquid
Physical properties
The pKa of (Diethylamino)ethyl methacrylate (DEAEMA) monomers is 8.8, while the pKa of these corresponding homopolymers is 7.5[1].
Uses
2-(Diethylamino)ethyl Methacrylate is used in preparation method and application of Hydrogel assembled self-adhesive material.
General Description
A clear light colored liquid. Insoluble in water and slightly denser than water. Flash point between 100-141°F. May be toxic by ingestion. Contact may severely irritate skin.
Air & Water Reactions
Flammable. Insoluble in water.
Reactivity Profile
An acrylic acid ester/amine. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Flammability and Explosibility
Non flammable
Synthesis
80-62-6
100-37-8
105-16-8
(1) Synthesis step: In a 1000 mL three-necked flask equipped with a stirrer, a thermometer and a moisture separator, 240 g (2.4 mol) of methyl methacrylate, 117 g (1.0 mol) of diethylaminoethanol, 200 g of n-hexane, 8 g of lithium hydroxide, and 0.5 g of phenothiazine were added sequentially. The reaction mixture was heated to 65 °C to 73 °C and kept at reflux to separate the resulting methanol. The reaction was continued until no methanol was separated (about 5 hours) and a total of 34.5 g of methanol was collected. The content of methanol was 88.6% and the content of methyl methacrylate was 11.2% by gas chromatography. (2) Purification step: After the reaction mixture was cooled to room temperature, it was washed twice with 300 mL×2 deionized water. Subsequently, the pressure was gradually reduced (0 to 100 mmHg) at 60 °C to 100 °C to remove unreacted methyl methacrylate and diethylaminoethanol. Finally, diethylaminoethyl methacrylate was obtained by distillation at 5 to 10 mmHg and 90 °C to 100 °C under reduced pressure. The product 175.7 g (theoretical yield 185.26 g) was obtained in 94.1% yield. Gas chromatographic analysis showed that the content of diethylaminoethyl methacrylate in the product was 99.2%.
References
[1] Ali Darabi. “Nitroxide-Mediated Polymerization of 2-(Diethylamino)ethyl Methacrylate (DEAEMA) in Water.” Macromolecules 48 1 (2014): 72–80.
2-(Diethylamino)ethyl methacrylate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao RENAS Polymer Material Co.,Ltd. | 0532-0532-86867058 18562606086 | sales@qdrenas.com | China | 128 | 50 |
| Qingdao ZKHT Chemical Co., Ltd. | 532-86898076 | zkhtchem@163.com | China | 30 | 58 |
| Hubei Honghan Biotech Co., Ltd | 0719-0719-7199239 15675290733 | 121628410@qq.com | China | 21 | 58 |
| Shandong Jiapeng Fine Chemical Co., LTD | 13573364027 | 2902541824@qq.com | China | 127 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| MedicalChem(Yancheng)Manuf.Co.,Ltd | +86-515-84383180 | sales@medicalchem.com | China | 80 | 69 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
Related articles
- Synthesis and application of 2-(Diethylamino)ethyl methacrylate
- 2-(Diethylamino)ethyl methacrylate is characterized by high chemical reactivity and distinctive polymerization properties.
- Dec 15,2025
View Latest Price from 2-(Diethylamino)ethyl methacrylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-(Diethylamino)ethyl methacrylate
105-16-8
|
20kg | 99.5％ | 10 toms | Qingdao RENAS Polymer Material Co., Ltd. | ||
 |
2026-09-02 | 2-(Diethylamino)ethyl methacrylate
105-16-8
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-05-28 | Diethylaminoethyl Methacrylate
105-16-8
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 2-(Diethylamino)ethyl methacrylate
105-16-8
- $0.00
- 99.5％
- Qingdao RENAS Polymer Material Co., Ltd.
-
- 2-(Diethylamino)ethyl methacrylate
105-16-8
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Diethylaminoethyl Methacrylate
105-16-8
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
