5-Fluoroorotic acid hydrate 98
- CAS No.
- 220141-70-8
- Chemical Name:
- 5-Fluoroorotic acid hydrate 98
- Synonyms
- Fluoroorotic Monohydrate;5-Fluoroorotic acid hydrate 98;5-FOA (5-Fluoroorotic acid), Monohydrate;5-Fluoroorotic Acid Monohydrate (Ultra Pure);5-fluoro-2,4-dioxo-1H-pyrimidine-6-carboxylic acid;5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carboxylic acid hydrate;5-Fluoroorotic Acid Monohydrate (5-FOA Monohydrate) for molecular biology, 98%
- CBNumber:
- CB3499289
- Molecular Formula:
- C5H3FN2O4.H2O
- Molecular Weight:
- 192.1
- MDL Number:
- MFCD00150658
- MOL File:
- 220141-70-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 278 °C (dec.)(lit.) |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Aqueous Base (Heated), DMSO (Sparingly, Heated), Methanol (Sparingly), Water (Sl |
| form | Solid |
| color | Must be White |
| Water Solubility | Soluble in water, dimethyl sulfoxide, 50mg in 1ml (1:1 ammonium hydroxide: water) with gentle heating. |
| Merck | 14,4176 |
| BRN | 181933 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UV7800000 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933599590 | |||||||||
| NFPA 704 |
|
5-Fluoroorotic acid hydrate 98 price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0382 | 5-Fluoroorotic Acid Monohydrate >95.0%(HPLC)(T) | 220141-70-8 | 100mg | $17 | 2026-04-30 | Buy |
| TCI Chemical | F0382 | 5-Fluoroorotic Acid Monohydrate >95.0%(HPLC)(T) | 220141-70-8 | 1g | $42 | 2026-04-30 | Buy |
| Cayman Chemical | 17318 | 5-fluoro Orotic Acid (hydrate) ≥95% | 220141-70-8 | 500mg | $68 | 2026-04-30 | Buy |
| Cayman Chemical | 17318 | 5-fluoro Orotic Acid (hydrate) ≥95% | 220141-70-8 | 1g | $124 | 2026-04-30 | Buy |
| TRC | TRC-F595000-5G | 5-Fluoroorotic Acid Monohydrate (Ultra Pure) >95%(HPLC) | 220141-70-8 | 5g | $486 | 2026-06-03 | Buy |
5-Fluoroorotic acid hydrate 98 Chemical Properties, Uses, Production
Description
5-fluoro Orotic acid (5-FOA) is used to detect URA3 gene expression in yeast molecular genetic constructs. Yeast with an active URA3 gene, which encodes orotine-5''-monophosphate decarboxylase, converts 5-FOA to fluorodeoxyuridine, which is toxic to cells. Resistant strains of yeast that carry a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil.
Uses
5-Fluoroorotic Acid, Monohydrate (5-FOA) has become a valuable tool for research in the field of molecular genetics and has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5í-phosphate decarboxylation.
References
[1] F WINSTON. Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae.[J]. Genetics, 1984, 107 2: 179-197. DOI: 10.1093/genetics/107.2.179
5-Fluoroorotic acid hydrate 98 Preparation Products And Raw materials
5-Fluoroorotic acid hydrate 98 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| Supplier | Advantage |
|---|---|
| J & K SCIENTIFIC LTD. | 76 |
| Alfa Aesar | 84 |
| TCI (Shanghai) Development Co., Ltd. | 81 |
| Energy Chemical | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 64 |
| Spectrum Chemical Manufacturing Corp. | 60 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 80 |
| TCI Europe | 75 |
| TCI AMERICA | 75 |
| Clearsynth Labs Limited | 58 |
