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Boc-D-leucinol 97

CAS No.
142121-48-0
Chemical Name:
Boc-D-leucinol 97
Synonyms
tert-Butyl (1-hydroxy-4-methylpentan-2-yl)carbamate;Boc-DL-Leucinol;N-BOC-DL-LEUCINOL;Boc-D-leucinol 97;Boc-D-Leucinol;BOC-D-LEUCINOL 97 USP/EP/BP;(r)-n-(tert-butoxycarbonyl)leucinol;ert-butylN-(1-hydroxy-4-methylpentan-2-yl)carbamate;Carbamic acid, N-[1-(hydroxymethyl)-3-methylbutyl]-, 1,1-dimethylethyl ester
CBNumber:
CB3499799
Molecular Formula:
C11H23NO3
Molecular Weight:
217.31
MDL Number:
MFCD00235931
MOL File:
142121-48-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:05

Boc-D-leucinol 97 Properties

Boiling point 213 °C (lit.)
Density 0.983 g/mL at 25 °C (lit.)
refractive index n20/D 1.449(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
pka 12.11±0.46(Predicted)
optical activity [α]20/D +26°, c = 2 in methanol
Major Application peptide synthesis
InChI 1S/C11H23NO3/c1-8(2)6-9(7-13)12-10(14)15-11(3,4)5/h8-9,13H,6-7H2,1-5H3,(H,12,14)/t9-/m1/s1
InChIKey LQTMEOSBXTVYRM-SECBINFHSA-N
SMILES CC(C)C[C@H](CO)NC(=O)OC(C)(C)C
UNSPSC Code 12352200
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame Over Circle (GHS03)Exclamation Mark (GHS07)
GHS03,GHS07
Signal word  Warning
Hazard statements  H272-H315-H319
Precautionary statements  P221-P264b-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364-P370+P378r-P403-P501c
PPE Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
WGK Germany  3
HS Code  2924190090
Storage Class 10 - Combustible liquids

Boc-D-leucinol 97 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 552801 Boc-D-Leucinol 97% 142121-48-0 1g $84.2 2022-05-15 Buy
Biosynth SFA12148 Boc-DL-Leucinol 142121-48-0 5g $295 2026-06-05 Buy
Apolloscientific OR941390 Boc-DL-Leucinol 97% 142121-48-0 1g $204 2026-06-04 Buy
Apolloscientific OR941390 Boc-DL-Leucinol 97% 142121-48-0 5g $516 2026-06-04 Buy
aablocks AA001HQS N-BOC-DL-LEUCINOL 95% 142121-48-0 250mg $31 2026-05-28 Buy
Product number Packaging Price Buy
552801 1g $84.2 Buy
SFA12148 5g $295 Buy
OR941390 1g $204 Buy
OR941390 5g $516 Buy
AA001HQS 250mg $31 Buy

Boc-D-leucinol 97 Chemical Properties, Uses, Production

Uses

peptide synthesis

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

D/L-LEUCINOL

16369-17-8

Di-tert-butyl dicarbonate

24424-99-5

BOC-D-LEUCINOL  97

142121-48-0

(1) Di-tert-butyl dicarbonate (4.1 g) was slowly added to a solution of 2-amino-4-methylpentan-1-ol (2.0 g) in tetrahydrofuran (THF, 40 mL) and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting residue was washed with a solvent mixture of hexane/ethyl acetate (5:1, v/v) to afford the white solid product tert-butyl (1-hydroxy-4-methylpentan-2-yl)carbamate (3.7 g, yield XX%). The product was analyzed by electrospray ionization mass spectrometry (ESI-MS) showing m/z: 240 ([M + Na]+), which is consistent with the expected molecular weight.

References

[1] Patent: US2013/331571, 2013, A1. Location in patent: Paragraph 0179; 0180

Boc-D-leucinol 97 Preparation Products And Raw materials

Raw materials

Preparation Products

Boc-D-leucinol 97 Suppliers

Global Suppliers ( 59)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
ITIC MEDCHEM(SUZHOU) CO.,LTD. 0512-68323967 18015559028 sales@iticmedchem.com China 528 61
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Chiral Chemicals Inc. 021-37285021 13472570865 tym7xi@aliyun.com China 299 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Yolne Chemical Co., Ltd. 021-62960152 934678158@qq.com China 9886 55
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9849 55
Shanghai Song Yuan Chemical Technology Co., Ltd. 010-1234567 18521000990 sonyuanchemical@163.com China 6467 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80

View Latest Price from Boc-D-leucinol 97 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BOC-D-LEUCINOL  97 pictures 2019-12-26 BOC-D-LEUCINOL 97
142121-48-0
$1.00 1g ≥98% Career Henan Chemical Co
Boc-DL-Leucinol (r)-n-(tert-butoxycarbonyl)leucinol N-BOC-DL-LEUCINOL ert-butylN-(1-hydroxy-4-methylpentan-2-yl)carbamate BOC-D-LEUCINOL 97 USP/EP/BP Carbamic acid, N-[1-(hydroxymethyl)-3-methylbutyl]-, 1,1-dimethylethyl ester Boc-D-Leucinol tert-Butyl (1-hydroxy-4-methylpentan-2-yl)carbamate Boc-D-leucinol 97 142121-48-0