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Boc-beta-cyclohexyl-Ala-OH

Boc-beta-cyclohexyl-Ala-OH structure

CAS No.: 37736-82-6

Chemical Name:: Boc-beta-cyclohexyl-Ala-OH

Synonyms: (S)-2-((tert-Butoxycarbonyl)aMino)-3-cyclohexylpropanoic acid;BOC-CHA-OH;BOC-L-CHA-OH;Boc-L-Cha-OH (Oil);BOC-L-CYCLOHEXYLALANINE;Boc-β-cyclohexyl-ala-OH;Boc-b-cyclohexyl-Ala-OH;BOC-3-CYCLOHEXYL-L-ALANINE;Boc-β-cyclohexyl-L-alanine;BOC-L-3-Cyclohexyl Alanine

CBNumber:: CB6129914

Molecular Formula:: C14H25NO4

Molecular Weight:: 271.35

MDL Number:: MFCD00076896

MOL File:: 37736-82-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:53:48

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Boc-beta-cyclohexyl-Ala-OH Properties

Boiling point	420.4±28.0 °C(Predicted)
Density	1.083±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	4.02±0.10(Predicted)
form	<40°C Solid,>42°C Liquid
Appearance	White to off-white <40°C Solid,>42°C Liquid
optical activity	[α]20/D 15.5±1°, c = 2% in glacial acetic acid
BRN	3060603
Major Application	peptide synthesis
InChI	InChI=1/C14H25NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h10-11H,4-9H2,1-3H3,(H,15,18)(H,16,17)/t11-/s3
InChIKey	MSZQAQJBXGTSHP-NSHDSACASA-N
SMILES	[C@H](C(=O)O)(NC(=O)OC(C)(C)C)CC1CCCCC1 \|&1:0,r\|
CAS DataBase Reference	37736-82-6(CAS DataBase Reference)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

WGK Germany

HazardClass

IRRITANT

HS Code

29242990

Storage Class

13 - Non Combustible Solids

NFPA 704

	1
0		0

Boc-beta-cyclohexyl-Ala-OH price More Price(55)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4244	Boc-Cha-OH	37736-82-6	5G	$146	2026-04-30	Buy
TCI Chemical	B4244	Boc-Cha-OH	37736-82-6	25G	$439	2026-04-30	Buy
Usbiological	266502	Boc-beta-cyclohexyl-L-alanine Asreported	37736-82-6	2g	$337	2026-06-03	Buy
Usbiological	266502	Boc-beta-cyclohexyl-L-alanine Asreported	37736-82-6	5g	$579	2026-06-03	Buy
Usbiological	266502	Boc-beta-cyclohexyl-L-alanine Asreported	37736-82-6	10g	$805	2026-06-03	Buy

Product number	Packaging	Price	Buy
B4244	5G	$146	Buy
B4244	25G	$439	Buy
266502	2g	$337	Buy
266502	5g	$579	Buy
266502	10g	$805	Buy

Boc-beta-cyclohexyl-Ala-OH Chemical Properties, Uses, Production

Chemical Properties

White crystalline powder

Uses

It is an agrochemical, organic and pharmaceutical intermediates.

Synthesis

24424-99-5

25528-71-6

37736-82-6

Step 2. Synthesis of (S)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropionic acid. (S)-2-amino-3-cyclohexylpropanoic acid hydrochloride (118 g, 0.57 mol) was dissolved in 0.5 N NaOH aqueous solution (1200 mL), followed by the addition of a solution of tetrahydrofuran (THF, 600 mL) of di-tert-butyl dicarbonate (Boc2O, 137 g, 0.63 mol). The reaction mixture was stirred for 2 hours. After completion of the reaction, the organic solvent was removed under reduced pressure. The aqueous phase was washed with ether (Et2O, 2 x 400 mL) to remove unreacted feedstock. Subsequently, the aqueous phase was acidified to pH 5 with aqueous 2 N HCl. The acidified aqueous phase was extracted with ethyl acetate (EtOAc, 3 × 400 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give the title compound (S)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoic acid (142 g, 92%) as an oil.1H NMR (CDCl3) δ: 0.92 (m, 1H), 1.09-1.30 (m, 3H), 1.48 (s, 9H), 1.51 (m, 1H), 1.52 (m, 1H), 1.66 (m, 5H), 1.78 (m, 1H), 4.32 (m, 1H), 4.88 (m, 1H), 8.55-9.48 (br s, 1H).

References

[1] Journal of Antibiotics, 1996, vol. 49, # 9, p. 909 - 920
[2] Patent: WO2007/117557, 2007, A2. Location in patent: Page/Page column 91
[3] Patent: US5756763, 1998, A

Boc-beta-cyclohexyl-Ala-OH Preparation Products And Raw materials

Raw materials

Di-tert-butyl dicarbonate H-Cha-OH HCl Sodium hydroxide Tetrahydrofuran Hydrochloric acid

Water

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Preparation Products

Boc-beta-cyclohexyl-Ala-OH Suppliers

Global Suppliers ( 167)

Supplier	Tel	Email	Country	ProdList	Advantage
Taizhou Tianhong Biochemistry Technology Co., Ltd.	0523-86132544 15366717810	sales@thbiochem.com	China	407	55
YangZhou Ruihong Biotech Co., Ltd.	0514-015380367604 15380367604	sales@ruibobiotech.com	China	509	55
Wuxi Lihengsheng Biopharmaceutical Technology Co., Ltd	15250805028 15250805028	649163353@qq.com	China	8000	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64

Supplier	Advantage
Taizhou Tianhong Biochemistry Technology Co., Ltd.	55
YangZhou Ruihong Biotech Co., Ltd.	55
Wuxi Lihengsheng Biopharmaceutical Technology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Alfa Aesar	84
Energy Chemical	61
GL Biochem (Shanghai) Ltd	64
Jia Xing Isenchem Co.,Ltd	66
Accela ChemBio Co.,Ltd.	64

View Latest Price from Boc-beta-cyclohexyl-Ala-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-07-13	BOC-BETA-CYCLOHEXYL-ALA-OH 37736-82-6	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	BOC-BETA-CYCLOHEXYL-ALA-OH 37736-82-6	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2019-12-27	BOC-BETA-CYCLOHEXYL-ALA-OH 37736-82-6	$1.00	1KG	99%	200kg	Career Henan Chemical Co

BOC-BETA-CYCLOHEXYL-ALA-OH
37736-82-6
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

BOC-BETA-CYCLOHEXYL-ALA-OH
37736-82-6
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

BOC-BETA-CYCLOHEXYL-ALA-OH
37736-82-6
$1.00
99%
Career Henan Chemical Co

Boc-beta-cyclohexyl-Ala-OH Spectrum

BOC-BETA-CYCLOHEXYL-ALA-OH(37736-82-6)¹HNMR

37736-82-6 (Boc-beta-cyclohexyl-Ala-OH) Related Search:

Boc-D-Abu-OH Boc-Abu-OH Boc-D-Phenylglycine Boc-beta-cyclohexyl-D-alanine monohydrate Boc-L-Cyclohexylglycine

(S)-2-((tert-butoxycarbonyl)amino)-4-cyclohexylbutanoic acid Boc-D-Serine Boc-alpha-Cyclohexyl-D-glycine L-Cyclohexylalanine Boc-Cha-OH dcha

Boc-Oic-OH Boc-L-cyclohexylalanine hydroxysuccinimide ester Boc-beta-cyclohexyl-Ala-OH Boc-3-cyclohexyl-L-alanine methyl ester (3S,4aR,8aR)-N-Boc-decahydroisoquinoline-3-carboxylic acid

(3S,4aS,8aS)-N-Boc-decahydroisoquinoline-3-carboxylic acid Boc-L-cyclohexylalanine 2H2O Boc-L-mecha-OH

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(S)-2-TERT-BUTOXYCARBONYLAMINO-3-CYCLOHEXYL-PROPIONIC ACID BOC-L-CYCLOHEXYLALANINE BOC-L-CHA-OH BOC-3-CYCLOHEXYL-L-ALANINE BOC-BETA-CYCLOHEXYL-ALANINE BOC-CHA-OH BOC-BETA-CYCLOHEXYL-L-ALANINE N-T-boc-B-cyclohexyl-L-alanine Boc-β-cyclohexyl-ala-OH (S)-2-(Boc-amino)-3-cyclohexylpropionic Acid (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-cyclohexylpropanoic acid (S)-2-(Tert-butoxycarbonylaMino)-3-cyclohexylpropanoic acid hydrate N-Boc-3-cyclohexyl-L-alanine, 98% Boc-b-cyclohexyl-Ala-OH Boc-(S)-3-Cyclohexylalanine Boc-β-cyclohexyl-L-alanine Boc-Cha-OH hydrate >=99.0% (TLC), ~1 mol/mol water BOC-L-3-Cyclohexyl Alanine Boc-?-cyclohexyl-L-alanine99% (Tert-Butoxy)Carbonyl Cha-OH NALPHA-tert-Butoxycarbonyl-3-cyclohexyl-L-alanine (S)-N-alpha-t-Butyloxycarbonyl-3-(cyclohexyl)-alanine (oil) Boc-L-Cha-OH (Oil) N-(tert-butoxycarbonyl)-beta-cyclohexyl-L-alanine Boc-3-cyclohexyl-L-alanine hydrate, Boc-hexahydro-L-phenylalanine BOC--Cyclohexyl Ala-OH hydrate Boc-hexahydro-L-phenylalanine Cyclohexanepropanoic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-,(aS)- (S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanoicaci BOC-BETA-CYCLOHEXYL-ALA-OH USP/EP/BP (S)-N-alpha-t-Butyloxycarbonyl-3-(cyclohexyl)-alanine (S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanoic Cyclohexanepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)- Boc-beta-cyclohexyl-L-alanine - 5 g (S)-2-((tert-Butoxycarbonyl)aMino)-3-cyclohexylpropanoic acid Boc-beta-cyclohexyl-Ala-OH 37736-82-6 C14H25NO4 Alanine Derivatives Specialty Synthesis Peptide Synthesis Unnatural Amino Acid Derivatives Peptide Amino Acids pharmacetical