TRAM-34
- CAS No.
- 289905-88-0
- Chemical Name:
- TRAM-34
- Synonyms
- RAM-34;CS-1574;TRAM34;TRAM 34;Triarylmethane-34;TRAM-34 USP/EP/BP;TRAM-34, 10 mM in DMSO;Clotrimazole Impurity 8;Des Imidazole 1-pyrazole;Clotrimazole TRAM-34 Impurity;TRAM34;TRAM 34;TRIARYLMETHANE-34
- CBNumber:
- CB3505056
- Molecular Formula:
- C22H17ClN2
- Molecular Weight:
- 344.84
- MDL Number:
- MFCD09842562
- MOL File:
- 289905-88-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| TRAM 34 ≥98% (HPLC), solid | T6700 | 5mg | $214 |
| TRAM 34 ≥98% (HPLC), solid | T6700 | 25mg | $673 |
| TRAM-34 ≥98% | 23385 | 5mg | $41 |
| TRAM-34 ≥98% | 23385 | 10mg | $75 |
| TRAM-34 ≥98% | 23385 | 25mg | $157 |
| More product size | |||
| Melting point | 145-147°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: ~11 mg/mL |
| form | solid |
| color | off-white |
| Water Solubility | Soluble in DMSO at 2mg/ml. Insoluble in water |
| InChI | InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H |
| InChIKey | KBFUQFVFYYBHBT-UHFFFAOYSA-N |
| SMILES | N1(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CC=N1 |
| CAS DataBase Reference | 289905-88-0 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H413 | |||||||||
| Precautionary statements | P273-P301+P312+P330 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 4 |
|||||||||
| NFPA 704 |
|
TRAM-34 price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T6700 | TRAM 34 ≥98% (HPLC), solid | 289905-88-0 | 5mg | $214 | 2026-04-30 | Buy |
| Sigma-Aldrich | T6700 | TRAM 34 ≥98% (HPLC), solid | 289905-88-0 | 25mg | $673 | 2026-04-30 | Buy |
| Cayman Chemical | 23385 | TRAM-34 ≥98% | 289905-88-0 | 5mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 23385 | TRAM-34 ≥98% | 289905-88-0 | 10mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 23385 | TRAM-34 ≥98% | 289905-88-0 | 25mg | $157 | 2026-04-30 | Buy |
TRAM-34 Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
TRAM-34 has been used to study its effect on the prevention of vascular restenosis after balloon angioplasty.
Definition
ChEBI: TRAM-34 is an organochlorine compound.
Biological Activity
Highly selective blocker of intermediate conductance Ca 2+ -activated K + channels (IK Ca 1, K Ca 3.1) (K d = 20 nM). Exhibits 200-1500-fold selectivity over K V , BK Ca , SK Ca , Na + , CRAC and Cl - channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.
Biochem/physiol Actions
TRAM-34 exhibits 100-fold selectivity (Kd = 20 nM) for IKCa1 channels over other K+ channels (Charybdotoxin, Kd = 5 nM, Clotrimazole, Kd = 70 nM; Nitrendipine Kd = 900 nM). Furthermore, TRAM-34 is known to suppress the activation of human T lymphocytes,.
storage
+4°C
TRAM-34 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20582 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
