NT5E/CD73 (D7F9A) Rabbit mAb
- CAS No.
- Chemical Name:
- NT5E/CD73 (D7F9A) Rabbit mAb
- Synonyms
- NT5E/CD73 (D7F9A) Rabbit mAb
- CBNumber:
- CB35667779
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
NT5E/CD73 (D7F9A) Rabbit mAb Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat
Background
Ecto-5'-nucleotidase is a 70 kDa glycosyl phosphatidylinositol-anchored, membrane-bound glycoprotein that catalyzes the hydrolysis of extracellular nucleoside monophosphates into bioactive nucleosides. NT5E catalyzes the terminal step of extracellular adenosine formation from adenosine monophosphate, which drives the regulation of extracellular adenosine levels and the downstream activation of the four G protein-coupled adenosine receptors. Binding of hypoxia-inducible factor to the NT5E gene promoter leads to upregulation of NT5E during hypoxia. The biological roles of NT5E include lymphocyte adhesion, fibrosis, and the regulation of nociception.
References
[1] Le Hir, M. and Kaissling, B. (1993) Am J Physiol 264, F377-87.
[2] Schulte, G. and Fredholm, B.B. (2003) Cell Signal 15, 813-27.
[3] Synnestvedt, K. et al. (2002) J Clin Invest 110, 993-1002.
[4] Arvilommi, A.M. et al. (1997) Eur J Immunol 27, 248-54.
[5] Airas, L. and Jalkanen, S. (1996) Blood 88, 1755-64.
[6] Peng, Z. et al. (2008) Nucleosides Nucleotides Nucleic Acids 27, 821-4.
[7] Sowa, N.A. et al. (2010) J Neurosci 30, 2235-44.
[8] Zylka, M.J. (2011) Trends Mol Med 17, 188-96.
NT5E/CD73 (D7F9A) Rabbit mAb Preparation Products And Raw materials
Raw materials
Preparation Products
NT5E/CD73 (D7F9A) Rabbit mAb Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Universal Biotech Co.,Ltd | 58 |
