ChemicalBook >> CAS DataBase List >>(-)-Donepezil

(-)-Donepezil

CAS No.
142057-80-5
Chemical Name:
(-)-Donepezil
Synonyms
(?)-Donepezil;S-(-)-DONEPEZIL;1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, (2S)-
CBNumber:
CB35985945
Molecular Formula:
C24H29NO3
Molecular Weight:
379.49
MDL Number:
MOL File:
142057-80-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51

(-)-Donepezil Properties

Melting point 108-110°C
Boiling point 527.9±50.0 °C(Predicted)
Density 1.141±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka 8.84±0.10(Predicted)
form Solid
color White to Off-White

(-)-Donepezil price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0113834 (S)-Donepezil 99.82% 142057-80-5 5mg $487 2026-06-04 Buy
ChemScene CS-0113834 (S)-Donepezil 99.82% 142057-80-5 10mg $780 2026-06-04 Buy
ChemScene CS-0113834 (S)-Donepezil 99.82% 142057-80-5 25mg $1571 2026-06-04 Buy
ChemScene CS-0113834 (S)-Donepezil 99.82% 142057-80-5 50mg $2492 2026-06-04 Buy
ChemScene CS-0113834 (S)-Donepezil 99.82% 142057-80-5 100mg $4008 2026-06-04 Buy
Product number Packaging Price Buy
CS-0113834 5mg $487 Buy
CS-0113834 10mg $780 Buy
CS-0113834 25mg $1571 Buy
CS-0113834 50mg $2492 Buy
CS-0113834 100mg $4008 Buy

(-)-Donepezil Chemical Properties, Uses, Production

Uses

(-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.

Definition

ChEBI: Donepezil is a racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a nootropic agent and an EC 3.1.1.8 (cholinesterase) inhibitor. It contains a (R)-donepezil and a (S)-donepezil. It is a conjugate base of a donepezil (1+).

(-)-Donepezil Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-Donepezil Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
LGC Science (Shanghai) Ltd. 17717235263 17717235263 offer.de@lgcgroup.com China 38135 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from (-)-Donepezil manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(-)-Donepezil pictures 2026-05-11 (-)-Donepezil
142057-80-5
$1450.00-2500.00 10g TargetMol Chemicals Inc.
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, (2S)- S-(-)-DONEPEZIL (?)-Donepezil 142057-80-5