LUCIFERASE
- CAS No.
- 61970-00-1
- Chemical Name:
- LUCIFERASE
- Synonyms
- RFLuc;Ultra-Glo;LUCIFERASE;EC 1.14.14.3;EC 1.13.12.7;Luciferase from;Einecs 263-359-4;Beetle luciferase;LUCIFERASE FIREFLY;FIREFLY LUCIFERASE
- CBNumber:
- CB3663963
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131546
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Luciferase from Photinus pyralis (firefly) recombinant, expressed in E. coli, buffered aqueous solution, ≥10×1010 units/mg protein | L9420 | 1mg | $136 |
| Luciferase from Photinus pyralis (firefly) recombinant, expressed in E. coli, buffered aqueous solution, ≥10×1010 units/mg protein | L9420 | 5x1mg | $547 |
| Luciferase (firefly recombinant) ≥95% estimated by SDS-PAGE | 20398 | 1mL | $130 |
| Luciferase from recombinant, expressed in E. coli, lyophilized powder, ≥1×1011 units/mg protein | SRE0045 | 1mg | $132 |
| Luciferase from recombinant, expressed in E. coli, lyophilized powder, ≥1×1011 units/mg protein | SRE0045 | 2mg | $248 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H373 |
| Precautionary statements | P260-P264-P270-P301+P312-P314-P501 |
| Hazard Codes | Xi,Xn,T |
| Risk Statements | 36/37/38-22-52/53-45 |
| Safety Statements | 26-36/37-24/25-23-22-61-45-53 |
| WGK Germany | 3 |
| F | 3-10-21 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Resp. Sens. 1 |
LUCIFERASE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L9420 | Luciferase from Photinus pyralis (firefly) recombinant, expressed in E. coli, buffered aqueous solution, ≥10×1010 units/mg protein | 61970-00-1 | 1mg | $136 | 2025-07-31 | Buy |
| Sigma-Aldrich | L9420 | Luciferase from Photinus pyralis (firefly) recombinant, expressed in E. coli, buffered aqueous solution, ≥10×1010 units/mg protein | 61970-00-1 | 5x1mg | $547 | 2025-07-31 | Buy |
| Cayman Chemical | 20398 | Luciferase (firefly recombinant) ≥95% estimated by SDS-PAGE | 61970-00-1 | 1mL | $130 | 2024-03-01 | Buy |
| Sigma-Aldrich | SRE0045 | Luciferase from recombinant, expressed in E. coli, lyophilized powder, ≥1×1011 units/mg protein | 61970-00-1 | 1mg | $132 | 2025-07-31 | Buy |
| Sigma-Aldrich | SRE0045 | Luciferase from recombinant, expressed in E. coli, lyophilized powder, ≥1×1011 units/mg protein | 61970-00-1 | 2mg | $248 | 2025-07-31 | Buy |
LUCIFERASE Chemical Properties,Uses,Production
Description
Luciferase (firefly recombinant) is a light-generating enzyme that catalyzes an oxidative reaction, using luciferin, ATP, and molecular oxygen to produce oxyluciferin, which yields visible light. The bioluminescence of this ATP-dependent luciferase is commonly used in reporter systems that are amenable to high-throughput screening.
Uses
Firefly luciferase is used extensively in molecular and cell biology, in particular for the efficient detection and quantitation of ATP and as a reporter for genetic function.
Uses
Luciferase from Photinus pyralis (firefly) has been used as a component of lysis solution to measure luminescence signals, as part of the study to determine chemical signals which can activate the karrikin insensitive 2 (KAI2) pathway.
General Description
Firefly luciferase catalyzes the reaction of luciferin with ATP and leads to the production of yellow-green light. The enzyme has a molecular weight of 62kDa and is expressed in peroxisomes. Luciferase is considered as a model to study protein–anesthetic interactions. Firefly luciferase is highly useful in cell biology and molecular biology, as a reporter of gene function and for the quantification of ATP.
Biochem/physiol Actions
Firefly luciferase is a 62 kDa protein that catalyzes the production of light. The enzyme requires ATP, molecular oxygen, and the heterocyclic compound, firefly luciferin, to generate light in a two-step process. The light producing reaction is initiated by luciferin activation (adenylation of its carboxylate group) and proceeds in the presence of molecular oxygen to yield a photon of yellow-green light.
Description
Luciferase produced in E.Coli is a single, non-glycosylated polypeptide chain containing 571 amino acids (1-550 a.a.) and having a molecular mass of 62.9kDa.
Luciferase is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Luciferase is a general term for the class of oxidative enzymes used in bioluminescence and is distinct from a photoprotein. Luciferase catalyzes a bioluminescent reaction which involves the substrate luciferin as well as Mg2+ and ATP, produces green light with a wavelength of 562 nm. Luciferase from firefly is broadly used as a reporter for studying gene regulation and function, and for pharmaceutical screening.
References
[1] BALDWIN T O. Firefly luciferase: the structure is known, but the mystery remains.[J]. Structure, 1996, 4 3: 223-228. DOI: 10.1016/s0969-2126(96)00026-3
[2] TINGTING XU. The Expanding Toolbox of In Vivo Bioluminescent Imaging.[J]. Frontiers in Oncology, 2016: 150. DOI: 10.3389/fonc.2016.00150
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
LUCIFERASE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39043 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8496 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046; | sales01@watsonbiotech.cn | China | 5743 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9844 | 58 |
View Lastest Price from LUCIFERASE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-04 | Luciferase, firefly
61970-00-1
|
US $1220.00-347.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2019-07-06 | N-Benzoylglycyl-3-methylphenylalanine
61970-00-1
|
US $1.00 / kg | 1kg | 95%-99% | as request | Career Henan Chemical Co |
-
- Luciferase, firefly
61970-00-1
- US $1220.00-347.00 / mg
- TargetMol Chemicals Inc.
-
- N-Benzoylglycyl-3-methylphenylalanine
61970-00-1
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
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