5-Amino-3-methylisoxazole
- CAS No.
- 14678-02-5
- Chemical Name:
- 5-Amino-3-methylisoxazole
- Synonyms
- 3-METHYLISOXAZOL-5-AMINE;3-METHYL-ISOXAZOL-5-YLAMINE;NSC 93421;AKOS PAO-1620;BUTTPARK 94\04-02;TIMTEC-BB SBB006539;3-methyl-5-isoxazolamin;3-Methyl-5-isoxazolamine;5-Amino-3-methylisoxazole;5-Isoxazolamine, 3-methyl-
- CBNumber:
- CB3683565
- Molecular Formula:
- C4H6N2O
- Molecular Weight:
- 98.1
- MDL Number:
- MFCD00003151
- MOL File:
- 14678-02-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 85-87 °C(lit.) |
|---|---|
| Boiling point | 231.3±20.0℃ (760 Torr) |
| Density | 1.167±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.4327 (estimate) |
| Flash point | 93.7±21.8℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform, Methanol (Slightly) |
| pka | -0.59±0.50(Predicted) |
| form | Crystalline Powder and Chunks |
| color | Yellow to orange-brown |
| λmax | 242nm(MeOH)(lit.) |
| BRN | 107906 |
| InChI | 1S/C4H6N2O/c1-3-2-4(5)7-6-3/h2H,5H2,1H3 |
| InChIKey | FNXYWHTZDAVRTB-UHFFFAOYSA-N |
| SMILES | Cc1cc(N)on1 |
| CAS DataBase Reference | 14678-02-5(CAS DataBase Reference) |
| FDA UNII | 0G66R1H4RW |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | KEEP COLD | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Amino-3-methylisoxazole price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 304271 | 5-Amino-3-methylisoxazole 98% | 14678-02-5 | 5g | $70.8 | 2023-01-07 | Buy |
| Sigma-Aldrich | 304271 | 5-Amino-3-methylisoxazole 98% | 14678-02-5 | 1g | $38.3 | 2022-05-15 | Buy |
| TCI Chemical | A2867 | 5-Amino-3-methylisoxazole >97.0%(T) | 14678-02-5 | 1g | $29 | 2026-04-30 | Buy |
| TCI Chemical | A2867 | 5-Amino-3-methylisoxazole >97.0%(T) | 14678-02-5 | 5g | $103 | 2026-04-30 | Buy |
| Usbiological | 258524 | 5-Amino-3-methylisoxazole Asreported | 14678-02-5 | 5g | $396 | 2026-06-03 | Buy |
5-Amino-3-methylisoxazole Chemical Properties,Uses,Production
Chemical Properties
yellow to orange-brown crystalline powder
Uses
5-Amino-3-methylisoxazole is a widely used reactant. 5-Amino-3-methylisoxazole has been used as a reactant for the preparation of heterocycle fused pyridinecarboxylic acids.
General Description
5-Amino-3-methylisoxazole reacts with α,β-unsaturated ketones to yield the corresponding isoxazolo[5,4-b]pyridines.
Synthesis
870-64-4
14678-02-5
Example 10 Preparation of 3-methyl-5-aminoisoxazole (STR35): hydroxylamine hydrochloride (34.81 g, 0.50 mol) was dissolved in 100 mL of water and the solution was cooled in an ice bath for 10 minutes. Subsequently, 3-aminocrotononitrile (48.30 g, 85% purity, 0.50 mol) was added in batches over 10 min. After stirring for 30 minutes, the solution was observed to turn orange and a solid precipitated. The solid was collected by filtration and recrystallized from benzene to give the final white solid product 3-methyl-5-aminoisoxazole (30.98 g, 63.2% yield) with a melting point ranging from 77°C to 79°C. The solid was collected by filtration and recrystallized from benzene to give the final white solid product 3-methyl-5-aminoisoxazole (30.98 g, 63.2% yield).
References
[1] Patent: US5252538, 1993, A
5-Amino-3-methylisoxazole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Lastest Price from 5-Amino-3-methylisoxazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | 5-AMINO-3-METHYLISOXAZOLE
14678-02-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 5-AMINO-3-METHYLISOXAZOLE
14678-02-5
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 5-AMINO-3-METHYLISOXAZOLE
14678-02-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-AMINO-3-METHYLISOXAZOLE
14678-02-5
- $1.00
- 98%
- Career Henan Chemical Co
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