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4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE

CAS No.
62968-37-0
Chemical Name:
4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE
Synonyms
4-(2-Chloropyrimidin-4-yl);2-Chloro-4-morpholine pyrimidine;4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE;4-(2-CHLORO-PYRIMIDIN-4-YL)-MORPHOLINE;Morpholine, 4-(2-chloro-4-pyrimidinyl)-
CBNumber:
CB3689411
Molecular Formula:
C8H10ClN3O
Molecular Weight:
199.64
MDL Number:
MFCD00981910
MOL File:
62968-37-0.mol
MSDS File:
SDS
Last updated:2026-05-28 04:27:11
Product description Number Pack Size Price
4-(2-chloropyrimidin-4-yl)morpholine 95% OR959389 100mg $32
4-(2-chloropyrimidin-4-yl)morpholine 95% OR959389 250mg $41
4-(2-chloropyrimidin-4-yl)morpholine 95% OR959389 500mg $56
4-(2-chloropyrimidin-4-yl)morpholine 95% OR959389 1g $85
4-(2-chloropyrimidin-4-yl)morpholine 95% OR959389 5g $376

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2934999090

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR959389 4-(2-chloropyrimidin-4-yl)morpholine 95% 62968-37-0 100mg $32 2026-06-04 Buy
Apolloscientific OR959389 4-(2-chloropyrimidin-4-yl)morpholine 95% 62968-37-0 250mg $41 2026-06-04 Buy
Apolloscientific OR959389 4-(2-chloropyrimidin-4-yl)morpholine 95% 62968-37-0 500mg $56 2026-06-04 Buy
Apolloscientific OR959389 4-(2-chloropyrimidin-4-yl)morpholine 95% 62968-37-0 1g $85 2026-06-04 Buy
Apolloscientific OR959389 4-(2-chloropyrimidin-4-yl)morpholine 95% 62968-37-0 5g $376 2026-06-04 Buy
Product number Packaging Price Buy
OR959389 100mg $32 Buy
OR959389 250mg $41 Buy
OR959389 500mg $56 Buy
OR959389 1g $85 Buy
OR959389 5g $376 Buy

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Chemical Properties,Uses,Production

Synthesis

Morpholine

110-91-8

2,4-Dichloropyrimidine

3934-20-1

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE

62968-37-0

General procedure: 2,4-Dichloropyrimidine (1.0 g, 6.7 mmol) was suspended in ethanol (20 ml) under inert atmosphere, cooled to 0°C and stirred. To this suspension triethylamine (1.4 ml, 10.1 mmol) and morpholine (0.59 ml, 6.7 mmol) were added sequentially. The reaction mixture was stirred at 0°C for 3 hours. After completion of the reaction, the mixture was concentrated in vacuum, diluted with 1 M NaOH solution (20 ml) and extracted with ethyl acetate (3 x 20 ml). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to give a colorless solid. The crude product was recrystallized by ethyl acetate/hexane to give 2-chloro-4-morpholino pyrimidine (1.21 g, 90% yield) as a colorless solid, which did not require further purification.LC-MS (ESP) analysis showed m/z 200 [M+H]+ and retention time (R/T) = 3.26 min.

References

[1] Patent: US2006/199804, 2006, A1. Location in patent: Page/Page column 27
[2] Tetrahedron, 2015, vol. 71, # 29, p. 4859 - 4867
[3] Organic Letters, 2018, vol. 20, # 2, p. 473 - 476
[4] Patent: WO2017/58503, 2017, A1. Location in patent: Page/Page column 419-421
[5] European Journal of Medicinal Chemistry, 1991, vol. 26, # 7, p. 729 - 733

110-91-8
3934-20-1
62968-37-0
Synthesis of 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE from Morpholine and 2,4-Dichloropyrimidine

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Preparation Products And Raw materials

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Suppliers

Global( 63)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7239 58
Accela ChemBio Inc.
+1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21135 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
Alfa Chemistry
+1-5166625404; Info@alfa-chemistry.com United States 20000 58
PT CHEM GROUP LIMITED
+86-85511178; +86-85511178 peter68@ptchemgroup.com China 35405 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49859 58
Aladdin Scientific
tp@aladdinsci.com United States 50108 58

View Lastest Price from 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(2-chloropyrimidin-4-yl)morpholine pictures 2025-05-23 4-(2-chloropyrimidin-4-yl)morpholine
62968-37-0
$10.00 1kg 99% 20 ton Hebei Zhuanglai Chemical Trading Co Ltd

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Spectrum

4-(2-Chloropyrimidin-4-yl) 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE 4-(2-CHLORO-PYRIMIDIN-4-YL)-MORPHOLINE Morpholine, 4-(2-chloro-4-pyrimidinyl)- 2-Chloro-4-morpholine pyrimidine 62968-37-0 62968-37-1 C8H10ClN3O Halides Pyrazines, Pyrimidines & Pyridazines Pyrazines, Pyrimidines & Pyridazines