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2-Amino-4-chloro-6-methoxypyrimidine

2-Amino-4-chloro-6-methoxypyrimidine Structure
2-Amino-4-chloro-6-methoxypyrimidine structure
CAS No.
5734-64-5
Chemical Name:
2-Amino-4-chloro-6-methoxypyrimidine
Synonyms
ACMP;2-Pyrimidinamine, 4-chloro-6-methoxy-;TIMTEC-BB SBB003975;2-amino-4-chloro-6-methoxypyri;2-Amino-4-methoxy-6-chloropyri;4-chloro-6-methoxy-2-pyrimidinamin;2-AMino-4-chloro-6-MethylyriMidine;4-Chloro-6-methoxy-2-pyrimidinamine;2-amino-4-chloro-6-methoxypyrimidne;4-methoxy-6-chloro-2-aminopyrimidine
CBNumber:
CB4707363
Molecular Formula:
C5H6ClN3O
Molecular Weight:
159.57
MDL Number:
MFCD00233535
MOL File:
5734-64-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:51
Product description Number Pack Size Price
2-Amino-4-chloro-6-methoxypyrimidine 95% 518646 10g $55.9
2-Amino-4-chloro-6-methoxypyrimidine 95% 518646 50g $164
2-Amino-4-chloro-6-methoxypyrimidine >95.0%(HPLC)(T) A1520 5g $21
2-Amino-4-chloro-6-methoxypyrimidine >95.0%(HPLC)(T) A1520 25g $23
2-Amino-6-chloro-4-methoxypyrimidine 295304 5g $275
More product size
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2-Amino-4-chloro-6-methoxypyrimidine Properties

Melting point 168-171 °C (lit.)
Boiling point 349.4±45.0 °C(Predicted)
Density 1.6625 (rough estimate)
refractive index 1.4510 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 1.96±0.10(Predicted)
form Crystalline Powder
color Light yellow
CAS DataBase Reference 5734-64-5(CAS DataBase Reference)
EWG's Food Scores 1
EPA Substance Registry System 2-Pyrimidinamine, 4-chloro-6-methoxy- (5734-64-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-2
WGK Germany  1
RTECS  UV6260335
TSCA  Yes
HazardClass  IRRITANT
HS Code  29335990
NFPA 704
1
2 0

2-Amino-4-chloro-6-methoxypyrimidine price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 518646 2-Amino-4-chloro-6-methoxypyrimidine 95% 5734-64-5 10g $55.9 2023-06-20 Buy
Sigma-Aldrich 518646 2-Amino-4-chloro-6-methoxypyrimidine 95% 5734-64-5 50g $164 2023-06-20 Buy
TCI Chemical A1520 2-Amino-4-chloro-6-methoxypyrimidine >95.0%(HPLC)(T) 5734-64-5 5g $21 2025-07-31 Buy
TCI Chemical A1520 2-Amino-4-chloro-6-methoxypyrimidine >95.0%(HPLC)(T) 5734-64-5 25g $23 2025-07-31 Buy
Usbiological 295304 2-Amino-6-chloro-4-methoxypyrimidine 5734-64-5 5g $275 2021-12-16 Buy
Product number Packaging Price Buy
518646 10g $55.9 Buy
518646 50g $164 Buy
A1520 5g $21 Buy
A1520 25g $23 Buy
295304 5g $275 Buy

2-Amino-4-chloro-6-methoxypyrimidine Chemical Properties,Uses,Production

Chemical Properties

light yellow crystalline powder

Uses

2-Amino-4-chloro-6-methoxy-pyrimidine is one of the two major metabolites formed in the degradation of chlorimuron-ethyl; a pre- and post-emergence herbicide for the control of important broad-leaved weeds in soybean and maize.

Synthesis

Methanol

67-56-1

2-Amino-4,6-dichloropyrimidine

56-05-3

2-Amino-4-chloro-6-methoxypyrimidine

5734-64-5

GENERAL PROCEDURE: Intermediate Id-f was prepared similarly to Intermediate Ia-c. Anhydrous tetrahydrofuran (12 mL) solution of sodium hydride (5.8 mmol) was cooled to 0 °C under nitrogen protection, followed by slow dropwise addition of substitutional alcohol (6.1 mmol). The reaction mixture was kept stirred at 0 °C for 15 min. Then, 2-amino-4,6-dichloropyrimidine (5.8 mmol) was added to the reaction system. The reaction temperature was raised to 62°C and the reaction was continued for 15 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched with 1 M hydrochloric acid solution (1 mL). The reaction mixture was diluted with ethyl acetate (20 mL), washed twice sequentially with saturated sodium bicarbonate solution (20 mL) and brine (20 mL), and the organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure. Finally, the residue was purified by silica gel column chromatography (ethyl acetate/petroleum ether as eluent) to afford the target compound Id-f. 4-Chloro-6-methoxypyrimidin-2-amine (Id) was a white solid with a melting point of 165-167 °C in 84% yield.1H-NMR (CDCl3) δ 6.04 (s, 1H, ArH), 5.35-5.14 (m, 2H , NH2), 3.81 (s, 3H, OCH3).

References

[1] Patent: WO2004/37795, 2004, A1. Location in patent: Page/Page column 8
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[3] Molecules, 2018, vol. 23, # 9,
[4] Nippon Kagaku Zasshi, 1953, vol. 74, p. 624
[5] Chem.Abstr., 1954, p. 13693

2-Amino-4-chloro-6-methoxypyrimidine Preparation Products And Raw materials

Raw materials

Methanol 2-Amino-4,6-dichloropyrimidine Sodium Methoxide Sodium hydride Tetrahydrofuran

Preparation Products

2-Amino-4-chloro-6-methoxypyrimidine Suppliers

Global( 362)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8772 58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		+8613288715578 sales@sichuanzyyt.com China 12247 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29850 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8826 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
SIMAGCHEM CORP 		58

View Lastest Price from 2-Amino-4-chloro-6-methoxypyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-4-chloro-6-methoxypyrimidine pictures 2025-10-21 2-Amino-4-chloro-6-methoxypyrimidine
5734-64-5
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Amino-4-chloro-6-methoxypyrimidine pictures 2025-08-08 2-Amino-4-chloro-6-methoxypyrimidine
5734-64-5
 US $0.00 / KG 1KG 99% 50000KG/month Sichuan Zhuoyu Yantang Technology Co., Ltd.
2-Amino-4-chloro-6-methoxypyrimidine pictures 2025-06-25 2-Amino-4-chloro-6-methoxypyrimidine
5734-64-5
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd

2-Amino-4-chloro-6-methoxypyrimidine Spectrum

2-Amino-4-chloro-6-methoxypyrimidine(5734-64-5)1HNMR

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2-AMINO-4-CHLORO-6-METHOXYPYRIMIDINE 2-AMINO-4-METHOXY-6-CHLORO PYRIMIDINE 2-AMINO-6-CHLORO-4-METHOXYPYRIMIDINE 4-Chloro-6-methoxy-2-pyrimidinamine 4-CHLORO-6-METHOXY-2-PYRIMIDINYLAMINE 4-CHLORO-6-METHOXY-PYRIMIDIN-2-AMINE 4-CHLORO-6-METHOXY-PYRIMIDIN-2-YLAMINE 4-chloro-6-methoxy-2-pyrimidinamin 4-methoxy-6-chloro-2-aminopyrimidine 2-amino-4-Chlorine-6-methoxypyrimidine 2-Amino-4-chloro-6-methoxylpyrimidine ACMP TIMTEC-BB SBB003975 2-amino-4-chloro-6-methoxypyri 2-Amino-4-methoxy-6-chloropyri 2-AMINO-4-CHLORO-6-METHOXYPYRIMIDINE(2-AMINO-4-METHOXY-6-CHLOROPYRIMIDINE) 2-amino-4-chloro-6-methoxypyrimidne 2-AMINO-4-CHLORO-6-METHOXYPYRIMIDINE 97% 2-Amino-4-chloro-6-methoxypyrimidine ,98% 6-Chloro-4-methoxypyrimidine-2-amine 2-Amino-6-chloro-4-methoxypyrimidine,98% 2-Amino-4-chloro-6-methoxypyrimidine,95% 2-AMino-4- chloro-6-MethoxypyriMidine , 4-Chloro-6-Methoxy-2-pyriMidinaMine 2-Pyrimidinamine, 4-chloro-6-methoxy- 2-AMino-4-chloro-6-MethylyriMidine 4-Chloro-6-methoxypyrimidin-2-amine, 2-Amino-4-chloro-6-methoxy-1,3-diazine 2-Amino-4-chloro-6-methoxypyrimidine > 2-Amino-4-chloro-6-methoxypyrimidine ISO 9001：2015 REACH 4-Chloro-6-methoxypyrimidin-2-amine - [C71535] 5734-64-5 5743-64-5 C5H6N3OCl C5H6ClN3O Building Blocks Pyrimidines Heterocyclic Building Blocks Halogenated Heterocycles Heterocycle-Pyrimidine series Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks PyrimidinesHeterocyclic Building Blocks Pyrimidines Pyrimidine Pyridines, Pyrimidines, Purines and Pteredines