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2,2'-Bis[(4S)-4-benzyl-2-oxazoline]

CAS No.
133463-88-4
Chemical Name:
2,2'-Bis[(4S)-4-benzyl-2-oxazoline]
Synonyms
SF140046;(S,S)-Bn-Bisbox;-Bis[(4S)-4-benzyl-2-oxazoline;2,2'-BIS[(4S)-4-BENZYL-2-OXAZOLINE;2,2'-Bis[(4S)-4-benzyl-2-oxazoline];(s,s)-2,2'-bis(4-benzyl-2-oxazoline);(S,S)-4,4'-dibenzyl-2,2'-bi(2-oxazoline);2,2′-Bis[(4S)-4-benzyl-2-oxazoline];2,2′-Bis[(4S)-4-benzyl-2-oxazoline], CAS 133463-88-4;(2S,2’S)-4,4’-Dibenzyl-2,2’,5,5’-tetrahydro-2,2’-bioxazole
CBNumber:
CB3689734
Molecular Formula:
C20H20N2O2
Molecular Weight:
320.39
MDL Number:
MFCD00191793
MOL File:
133463-88-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:08

2,2'-Bis[(4S)-4-benzyl-2-oxazoline] Properties

Melting point 129-132 °C(lit.)
Boiling point 449.3±28.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka 3.89±0.70(Predicted)
Appearance White to off-white Solid
optical activity [α]20/D 40.6°, c = 1 in ethanol
BRN 4756827
InChI 1S/C20H20N2O2/c1-3-7-15(8-4-1)11-17-13-23-19(21-17)20-22-18(14-24-20)12-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2/t17-,18-/m0/s1
InChIKey OIEQQWQZUYZCRJ-ROUUACIJSA-N
SMILES C1OC(=N[C@H]1Cc2ccccc2)C3=N[C@H](CO3)Cc4ccccc4
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

2,2'-Bis[(4S)-4-benzyl-2-oxazoline] price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 405973 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] 98% 133463-88-4 250mg $118 2026-04-30 Buy
Sigma-Aldrich 405973 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] 98% 133463-88-4 1g $346 2026-04-30 Buy
TCI Chemical B6639 2,2'-Bis[(4S)-4-benzyl-2-oxazoline] min. 98.0 % 133463-88-4 200MG $100 2026-04-30 Buy
TCI Chemical B6639 2,2'-Bis[(4S)-4-benzyl-2-oxazoline] min. 98.0 % 133463-88-4 1G $300 2026-04-30 Buy
Synthonix D62836 (4S,4'S)-4,4'-Dibenzyl-4,4',5,5'-tetrahydro-2,2'-bioxazole >98% 133463-88-4 250mg $30 2026-05-06 Buy
Product number Packaging Price Buy
405973 250mg $118 Buy
405973 1g $346 Buy
B6639 200MG $100 Buy
B6639 1G $300 Buy
D62836 250mg $30 Buy

2,2'-Bis[(4S)-4-benzyl-2-oxazoline] Chemical Properties,Uses,Production

Uses

2,2′-Bis[(4S)-4-benzyl-2-oxazoline] can be used as:

  • A catalyst for the enantioselective hydrosilylation of ketones.
  • A Schiff base ligand in the preparation of rhodium(I) and palladium(II) coordination complexes.
  • A ligand in the formation of copper(I) halide complexes; applicable in the synthesis of coordination polymers.

133485-45-7
133463-88-4
Synthesis of 2,2'-Bis[(4S)-4-benzyl-2-oxazoline] from N~1~,N~2~-bis(1-benzyl-2-chloroethyl)ethanediamide

2,2'-Bis[(4S)-4-benzyl-2-oxazoline] Preparation Products And Raw materials

Raw materials

Preparation Products

2,2'-Bis[(4S)-4-benzyl-2-oxazoline] Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 zdcomcon@126.com China 4094 50
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai Chiral bio-compound co., Ltd. 021-5068 3667/17749785980/1029026415; 17749785980 1029026415@qq.com China 4501 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
LaaJoo 021-60702684 18516024827 huang.jiayi@sinocompound.com China 2280 58
Shandong Ono Chemical Co., Ltd. 0539-6362799 20) China 9998 58
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 24636 60
(4S,4'S)- 4,4',5,5'-tetrahydro-4,4'-bis(phenylmethyl)-2,2'-Bioxazole (S,S)-4,4'-dibenzyl-2,2'-bi(2-oxazoline) (s,s)-2,2'-bis(4-benzyl-2-oxazoline) (S,S)-2,2μ-Bis(4-benzyl-2-oxazoline), (S,S)-4,4μ-Dibenzyl-2,2μ-bi(2-oxazoline) 2,2′-Bis[(4S)-4-benzyl-2-oxazoline],(S,S)-2,2′-Bis(4-benzyl-2-oxazoline), (S,S)-4,4′-Dibenzyl-2,2′-bi(2-oxazoline) (4S,4'S)-4,4'-dibenzyl-4,4',5,5'-tetrahydro-2,2'-bioxazole SF140046 2,2'-Bioxazole, 4,4',5,5'-tetrahydro-4,4'-bis(phenylmethyl)-, (4S,4'S)- (S,S)-Bn-Bisbox (2S,2’S)-4,4’-Dibenzyl-2,2’,5,5’-tetrahydro-2,2’-bioxazole -Bis[(4S)-4-benzyl-2-oxazoline 2,2'-BIS[(4S)-4-BENZYL-2-OXAZOLINE 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] 2,2′-Bis[(4S)-4-benzyl-2-oxazoline], CAS 133463-88-4 2,2'-Bis[(4S)-4-benzyl-2-oxazoline] 133463-88-4 Privileged Ligands Asymmetric Synthesis BOX Chiral Catalysts, Ligands, and Reagents