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(DAP22)-SHK

(DAP22)-SHK Structure
(DAP22)-SHK structure
CAS No.
220384-25-8
Chemical Name:
(DAP22)-SHK
Synonyms
ShK-Dap22;(DAP22)-SHK;(DAP22)-STICHODACTYLA HELIANTHUS NEUROTOXIN;449:PN:WO2010108154 SEQID:317 claimed protein;(Dap??)-Stichodactyla helianthus Neurotoxin (ShK);(DAP22)-STICHODACTYLA HELIANTHUS NEUROTOXIN (SHK);H-ARG-SER-CYS-ILE-ASP-THR-ILE-PRO-LYS-SER-ARG-CYS-THR-ALA-PHE-GLN-CYS-LYS-HIS-SER-MET-DAP-TYR-ARG-LEU-SER-PHE-CYS-ARG-LYS-THR-CYS-GLY-THR-CYS-OH;(Dap 22)-Stichodactyla helianthus Neurotoxin (ShK) H-Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Dap-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys-OH (Disulfide bonds between Cys3 and Cys35/Cys12 and Cys28/Cys17 and Cys32)
CBNumber:
CB3703005
Molecular Formula:
C166H274N54O48S7
Molecular Weight:
0
MDL Number:
MFCD02264510
MOL File:
Mol file
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Request For Quotation

(DAP22)-SHK Properties

storage temp. -15°C
form Powder
Water Solubility Soluble to 1 mg/ml in water
Sequence Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-{Dpr}-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (Disulfide bridge:Cys3-Cys35;Cys12-Cys28;Cys17-Cys32)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H312-H332-H302
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501

(DAP22)-SHK price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 256658 ShK-Dap22 Asreported 220384-25-8 100ug $602 2026-06-03 Buy
Biosynth FD109217 (Dap 22)-Stichodactyla helianthus Neurotoxin (ShK) 220384-25-8 10ug $195.4 2026-06-04 Buy
Biosynth FD109217 (Dap 22)-Stichodactyla helianthus Neurotoxin (ShK) 220384-25-8 25ug $389 2026-06-04 Buy
Biosynth FD109217 (Dap 22)-Stichodactyla helianthus Neurotoxin (ShK) 220384-25-8 50ug $675.5 2026-06-04 Buy
Biosynth FD109217 (Dap 22)-Stichodactyla helianthus Neurotoxin (ShK) 220384-25-8 100ug $1175 2026-06-04 Buy
Product number Packaging Price Buy
256658 100ug $602 Buy
FD109217 10ug $195.4 Buy
FD109217 25ug $389 Buy
FD109217 50ug $675.5 Buy
FD109217 100ug $1175 Buy

(DAP22)-SHK Chemical Properties, Uses, Production

Uses

ShK-Dap22 is a potent Kv1.3-specific immunosuppressive Polypeptide. ShK-Dap22 is a selective Kv1.3 channel blocker with IC50s of 23 pM, 1.8 nM, 10.5 nM, 37 nM, and 39 nM for mKv1.3, mKv1.1, hKv1.6, mKv1.4, and rKv1.2 channels, respectively[1].

storage

Store at -20°C

References

[1] K Kalman, et al. ShK-Dap22, a Potent Kv1.3-specific Immunosuppressive Polypeptide. J Biol Chem. 1998 Dec 4;273(49):32697-707. DOI:10.1074/jbc.273.49.32697

(DAP22)-SHK Preparation Products And Raw materials

Raw materials

Preparation Products

(DAP22)-SHK Suppliers

Global Suppliers ( 50)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
Chengdu Youngshe Chemical Co., Ltd. +86-17380623303 Caroline@youngshechem.com China 4726 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19087 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Chengdu Peter-like Biotechnology Co., Ltd. 18108052721 2850505130@qq.com China 5037 58
Supplier Advantage
GL Biochem (Shanghai) Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
Nanjing Leon Biological Technology Co., Ltd. 55
Nanjing Peptide Biotech Ltd. 55
Chengdu Youngshe Chemical Co., Ltd. 58
Hangzhou Peptidego Biotech Co.,Ltd. 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. 58
BOC Sciences 58
Chengdu Peter-like Biotechnology Co., Ltd. 58

View Latest Price from (DAP22)-SHK manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(DAP22)-SHK pictures 2026-07-27 (DAP22)-SHK
220384-25-8
 1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
  • (DAP22)-SHK pictures
  • (DAP22)-SHK
    220384-25-8
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd

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(DAP22)-SHK (DAP22)-STICHODACTYLA HELIANTHUS NEUROTOXIN (DAP22)-STICHODACTYLA HELIANTHUS NEUROTOXIN (SHK) (Dap 22)-Stichodactyla helianthus Neurotoxin (ShK) H-Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Dap-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys-OH (Disulfide bonds between Cys3 and Cys35/Cys12 and Cys28/Cys17 and Cys32) ShK-Dap22 H-ARG-SER-CYS-ILE-ASP-THR-ILE-PRO-LYS-SER-ARG-CYS-THR-ALA-PHE-GLN-CYS-LYS-HIS-SER-MET-DAP-TYR-ARG-LEU-SER-PHE-CYS-ARG-LYS-THR-CYS-GLY-THR-CYS-OH 449:PN:WO2010108154 SEQID:317 claimed protein (Dap??)-Stichodactyla helianthus Neurotoxin (ShK) 220384-25-8 C166H268N54O48S7 C166H274N54O48S7