Guanosine-5'-diphosphate disodium salt
- CAS No.
- 7415-69-2
- Chemical Name:
- Guanosine-5'-diphosphate disodium salt
- Synonyms
- GDP;GDP.Na2;GDP*2Na;GDP, NA2H;5'-GDP-Na2;5'-GDP 3NA;5'-GDP,2Na;Guanosine-5'Einecs 231-026-2;en pyrophosphate)
- CBNumber:
- CB1124550
- Molecular Formula:
- C10H16N5NaO11P2
- Molecular Weight:
- 467.2
- MDL Number:
- MFCD00066538
- MOL File:
- 7415-69-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >280°C (dec.) |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: 50 mg/mL, clear, colorless |
| form | Powder |
| color | White |
| biological source |
Porcine brain microbial (Corynebacterium sp) synthetic |
| Water Solubility | Soluble in water |
| Stability | Hygroscopic |
| InChIKey | PVMPTWQLNDHIEV-NGPBCCOENA-N |
| SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=NC2C(NC(N)=NC1=2)=O)O.[NaH] |&1:1,2,3,15,r| |
| UNSPSC Code | 41106305 |
| NACRES | NA.51 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36/37/39-27-26 |
| WGK Germany | 3 |
| F | 3-10-21 |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
Guanosine-5'-diphosphate disodium salt price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 51060 | Guanosine 5′-diphosphate disodium salt ≥90% (HPLC) | 7415-69-2 | 100mg | $235 | 2026-04-30 | Buy |
| Sigma-Aldrich | 51060 | Guanosine 5′-diphosphate disodium salt ≥90% (HPLC) | 7415-69-2 | 500mg | $772 | 2026-04-30 | Buy |
| Usbiological | 296168 | Guanosine 5'-Diphosphate Disodium Salt ≥95%(HPLC) | 7415-69-2 | 1g | $319 | 2026-06-03 | Buy |
| Usbiological | 296168 | Guanosine 5'-Diphosphate Disodium Salt ≥95%(HPLC) | 7415-69-2 | 2g | $438 | 2026-06-03 | Buy |
| Usbiological | 296168 | Guanosine 5'-Diphosphate Disodium Salt ≥95%(HPLC) | 7415-69-2 | 5g | $628 | 2026-06-03 | Buy |
Guanosine-5'-diphosphate disodium salt Chemical Properties,Uses,Production
Uses
Guanosine 5'-diphosphate disodium salt is a useful research chemical.
Uses
Guanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
General Description
Guanosine 5′-diphosphate (GDP) is a purine nucleotide and is interconvertible to guanosine by the action of ectonucleotidases and by nucleoside phosphorylase into guanine. GDP is majorly acted upon by 5′‐ectonucleotidases in neuronal cells.
Biochem/physiol Actions
Guanosine based nucleosides play a key role in multiple cellular processes and generation growth factors. Elevated levels of guanosine 5′-diphosphate (GDP) is associated with the pathogenesis of neurological disorders. GDP is bound to G protein . G protein coupled receptors (GPCRs) activate G proteins by exchanging the bound GDP to GTP. GDP is potent inhibitor agent of hepcidin- ferroportin complex and may be effective for promoting erythropoiesis and treating anemia of inflammation(AI).
in vivo
Guanosine 5'-diphosphate disodium salt (30 mg/kg, i.p., a single dose for 24 h) combined with FeSO4 (2 mg/kg, i.p., a single dose for 24 h) suppresses the iron storage ferritin level, thus preventing Hepcidin (HY-P70400)-induced internalization of FPN with increased iron absorption in normal mice[2].
Guanosine 5'-diphosphate disodium salt (30 mL/kg, i.p., three times a week for two weeks) can improve turpentine-induced inflammatory anemia in mice[1].
| Animal Model: | Male BALB/c mice[2]. |
| Dosage: | 30 mL/kg |
| Administration: | Intraperitoneal injection (i.p.) |
| Result: | Increased hemoglobin levels and serum iron levels in the long-term dosing model. Decreased Hamp mRNA expression, and spleen iron content was reduced by 46% in the short-term dosing model. |
IC 50
Human Endogenous Metabolite
Guanosine-5'-diphosphate disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Richuan Biotechnology Co., Ltd. | 18930985832 | zhangqimeng@nucbiotech.com | China | 40 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Hongene Biotech Corporation | 021-64757213 | info@hongene.com | China | 672 | 61 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Wuhu Huaren Science and Technology Co., Ltd. | 5842013 18155347026 | xujuan@hdpharm.com | China | 255 | 64 |
| Wuhan Wei Shunda Technology Development Co., Ltd. | 86-027-88774375 | mwmwhot@163.com | China | 233 | 65 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Nanjing MeiBo Biological Technology Co., Ltd. | 025-58619198 | sales@mbbio.com | China | 319 | 60 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
View Lastest Price from Guanosine-5'-diphosphate disodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-11 | Guanosine-5'-diphosphate disodium salt
7415-69-2
|
1kg | 98%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-07-15 | Guanosine 5'-diphosphate disodium salt
7415-69-2
|
$30.00-64.00 | 99.40% | 10g | TargetMol Chemicals Inc. | ||
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2026-06-02 | Guanosine 5’-diphosphate disodium salt(GDP-Na2)
7415-69-2
|
1kg | ≥95.0% | 1000 kg | Hangzhou Meiya Pharmaceutical Co Ltd |
-

- Guanosine-5'-diphosphate disodium salt
7415-69-2
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Guanosine 5'-diphosphate disodium salt
7415-69-2
- $30.00-64.00
- 99.40%
- TargetMol Chemicals Inc.
-

- Guanosine 5’-diphosphate disodium salt(GDP-Na2)
7415-69-2
- ≥95.0%
- Hangzhou Meiya Pharmaceutical Co Ltd
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