GINSENOSIDE F2
- CAS No.
- 62025-49-4
- Chemical Name:
- GINSENOSIDE F2
- Synonyms
- GINSENOSIDE F2;Ginsenoside F2(AS);20(S)-Ginsenoside-F2;Ginsenoside F2, >=98%;-D-glucopyranosidederiv.;20(S)-Ginsenoside F2 ,98%;Ginsenoside F2 (Standard);Ginsenoside F2, 10 mM in DMSO;Ginsenoside F2, 98%, from Panax ginseng C. A. Mey.;(20S)-3β,20-Bis(β-D-glucopyranosyloxy)-5α-dammar-24-ene-12β-ol
- CBNumber:
- CB5316911
- Molecular Formula:
- C42H72O13
- Molecular Weight:
- 785.01
- MDL Number:
- MFCD06410948
- MOL File:
- 62025-49-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 195-200°C |
|---|---|
| Boiling point | 871.5±65.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 12.91±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | SWIROVJVGRGSPO-IGNDSYMUNA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
GINSENOSIDE F2 price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | G0581 | Ginsenoside F2 | 62025-49-4 | 25MG | $126 | 2026-04-30 | Buy |
| Cayman Chemical | 23435 | Ginsenoside F2 ≥95% | 62025-49-4 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 23435 | Ginsenoside F2 ≥95% | 62025-49-4 | 5mg | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 23435 | Ginsenoside F2 ≥95% | 62025-49-4 | 10mg | $219 | 2026-04-30 | Buy |
| Cayman Chemical | 23435 | Ginsenoside F2 ≥95% | 62025-49-4 | 25mg | $502 | 2026-04-30 | Buy |
GINSENOSIDE F2 Chemical Properties, Uses, Production
Description
Ginsenoside F2 is a ginsenoside that has been found in P. ginseng and has diverse biological activities. It increases the proliferation of human hair dermal papilla cells (HHDPCs) and HaCaT human keratinocytes when used at concentrations of 0.01, 0.1, and 1 μM. Ginsenoside F2 (0.5 and 2.5 mg/kg) induces hair growth and increases hair density following depilation in mice. It is cytotoxic to U373MG glioblastoma cells in vitro (IC50 = 50 μg/ml) and reduces tumor growth in a U373MG mouse xenograft model when administered at a dose of 35 mg/kg every other day. Ginsenoside F2 (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; ) in mice. It is a human intestinal bacterial metabolite of ginsenoside Rb1 via the intermediate ginsenoside Rd .
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from ginseng rhizomes and Gynostemma pentaphyllum.
Uses
Ginsenoside F2 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to regulate element-binding protein cleavage activating protein and transforming growth factor-β pathways. This control over apoptosis can lead to a control over hair growth and hair loss in mammals.
Definition
ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position.
Synthesis
52705-93-8
62025-49-4
GENERAL STEPS: In a 1-liter stirred kettle reactor, 200 mL of reaction mixture (containing 50 mM phosphate buffer, pH 5.5) was mixed with 5 mg/mL of substrate PPDGM and crude recombinant CcBg11A (final protein concentration of 1 mg/mL). The reaction conditions were set to 30°C and stirred at 100 rpm for 2 hours. After completion of the reaction, the mixture was extracted twice in equal volumes using n-butanol. The n-butanol extracts were combined, concentrated by vacuum evaporation, and purified by a preparative HPLC system (Shimadzu, Japan) using a Shim-pack PREP-ODS(H) column (20 mm × 250 mm, 5 μm). The elution conditions were as follows: flow rate of 5.0 mL/min and a gradient elution program (0-10 min, 32% acetonitrile aqueous solution; 10-40 min, acetonitrile concentration was increased from 32% to 60%; and 40-50 min, 60% acetonitrile was maintained). The elution process was monitored by absorbance at 203 nm, and eluates were collected every 5 mL. The eluates containing the target product were combined and finally concentrated by vacuum evaporation.
References
[1] Chemistry of Natural Compounds, 2014, vol. 50, # 4, p. 691 - 696
[2] Khim. Prir. Soedin., 2014, vol. 50, # 4, p. 598 - 603,6
[3] Journal of Molecular Catalysis B: Enzymatic, 2015, vol. 120, p. 60 - 67
GINSENOSIDE F2 Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Shenzhen Sungening Bio-Tech Co., Ltd | +86-0755-89668383 | sales@sungening.com | China | 1319 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
View Latest Price from GINSENOSIDE F2 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-12 | Ginsenoside F2
62025-49-4
|
$30.00-90.00 | 99.84% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-04-12 | GINSENOSIDE F2
62025-49-4
|
1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | ||
 |
2023-02-24 | Ginsenoside F2
62025-49-4
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Ginsenoside F2
62025-49-4
- $30.00-90.00
- 99.84%
- TargetMol Chemicals Inc.
-
- GINSENOSIDE F2
62025-49-4
- $0.00
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Ginsenoside F2
62025-49-4
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
