Ginsenoside Re
- CAS No.
- 52286-59-6
- Chemical Name:
- Ginsenoside Re
- Synonyms
- DCR-020;Panaxoside;NSC 308877;ginsenosideb2;GINSENOSIDE RE;Sanchinoside Re;98%byHPLC/CH90650;Re Ginsenoside Re;Ginsenoside Re-RM;Ginsenoside Re (P)
- CBNumber:
- CB5210824
- Molecular Formula:
- C48H82O18
- Molecular Weight:
- 947.17
- MDL Number:
- MFCD00133369
- MOL File:
- 52286-59-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 201~203℃ |
|---|---|
| Boiling point | 1011.8±65.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) |
| form | Solid |
| pka | 12.85±0.70(Predicted) |
| color | White to Off-White |
| Cosmetics Ingredients Functions |
HUMECTANT SKIN CONDITIONING ANTIOXIDANT |
| InChIKey | PWAOOJDMFUQOKB-WCZZMFLVSA-N |
| LogP | 4.750 (est) |
| CAS DataBase Reference | 52286-59-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 46F3R0BL3I |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
Ginsenoside Re price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML4125 | Ginsenoside Re ≥98% | 52286-59-6 | 10 mg | $106 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML4125 | Ginsenoside Re ≥98% | 52286-59-6 | 50 mg | $320 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHL89212 | Ginsenoside Re phyproof? Reference Substance | 52286-59-6 | 10mg | $228 | 2026-04-30 | Buy |
| Sigma-Aldrich | 77960 | Ginsenoside Re analytical standard | 52286-59-6 | 10mg | $165 | 2026-04-30 | Buy |
| Sigma-Aldrich | 03000590 | Ginsenoside Re primary pharmaceutical reference standard | 52286-59-6 | 10mg | $742 | 2026-04-30 | Buy |
Ginsenoside Re Chemical Properties, Uses, Production
Chemical Properties
White solid
Uses
Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.
Definition
ChEBI: Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent and a nephroprotective agent. It is a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a beta-D-glucoside, a ginsenoside, a tetracyclic triterpenoid, a disaccharide derivative and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.
in vivo
Ginsenoside Re reduces insulin resistance in 3T3-L1 adipocytes and high-fat diet (HFD) rats through inhibition of JNK and NF-κB activation[2]. Intraperitoneal injection of lipopolysaccharide (LPS) at a dose of 20 mg/kg is lethal to mice, and 70% to 80% of the mice die within 60 h. However, pretreatment of the mice with Rg1 or Ginsenoside Re increases their survival rates in a dose-dependent manner. With the doses of Rg1 or Ginsenoside Re increase from 2.5 to 5 mg/kg, the survival rate is elevated from 60% to 90% (Rg1) or from 30% to 40% (Ginsenoside Re). All the mice administered Rg1 at a minimal dose of 10 mg/kg are protected from death compared to 80% survival of mice treated with an equal dose of Ginsenoside Re. To protect all the mice, 20 mg/kg Ginsenoside Re is needed. To investigate the anti-inflammatory potential of Rg1 and Ginsenoside Re, 1 mg/kg Rg1 or Ginsenoside Re is injected into rats and then challenged the animals with LPS. The injection procedure itself causes a transient stress-induced increase in body temperature of ~1.2°C in each group. Thereafter, LPS-challenged rats without pretreatment develope a robust biphasic fever, with the first peak reaching ~1.5°C at 2 h and the second peak reaching 1.8°C at 4 h. In contrast, the temperature changes for the Rg1-, Ginsenoside Re-, and TAK-242-treated groups are only 0.9, 1.2, and 0.8°C at 2 h and 1.3, 1.4, and 1.0°C at 4 h, respectively. Pretreatment with Rg1, Ginsenoside Re, or TAK-242 significantly attenuates LPS-induced alterations in body temperature[3].
target
AMPK | TLR | p38MAPK | HO-1 | TNF-α | Potassium Channel | NO | Calcium Channel | ERK | Akt | mTOR | CD4 | Calcium Channel | c-Src | NOS
IC 50
Aβ1-40; Aβ1-42; NF-κB; JNK
Ginsenoside Re Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Zhongzhicheng Biotechnology Co., Ltd. | 13628624121 13628604890 | 1205052329@qq.com | China | 9955 | 58 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Nanjing Yuanzhi Biotechnology Co. Ltd. | 15805159960; | 1211550495@qq.com | China | 1797 | 58 |
| Nanjing Digger Medical Technology Co. Ltd. | 025-025-51191215 18013836722 | 2399235533@qq.com | China | 4932 | 58 |
| Nanjing Spring & Autumn Biological Engineering Co., Ltd. | 17388075642 13815430202 | sale02@cqherb.com | China | 261 | 59 |
| Nanjing bingcheng Biotechnology Co., Ltd. | 18805194892 | 2727751293@qq.com | China | 172 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | 13186333400 19299362551 | cuichengbio@163.com | China | 1931 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
Related articles
- Ginsenoside Re: Diverse Pharmacological Properties
- Ginsenoside Re exerts anti-inflammatory/neuroprotective effects, undergoes deglycosylation/oxidation metabolism, and enhances ....
- Dec 29,2025
View Latest Price from Ginsenoside Re manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-27 | Ginsenoside Re
52286-59-6
|
$43.00-98.00 | 99.49% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2025-02-13 | Ginsenoside Re
52286-59-6
|
$1.00 | 1g | 98% | 1000 | Apeloa production Co.,Limited | |
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2023-02-24 | Ginsenoside Re
52286-59-6
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-

- Ginsenoside Re
52286-59-6
- $43.00-98.00
- 99.49%
- TargetMol Chemicals Inc.
-

- Ginsenoside Re
52286-59-6
- $1.00
- 98%
- Apeloa production Co.,Limited
-

- Ginsenoside Re
52286-59-6
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.





