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Ginsenoside Re

CAS No.
52286-59-6
Chemical Name:
Ginsenoside Re
Synonyms
DCR-020;Panaxoside;NSC 308877;ginsenosideb2;GINSENOSIDE RE;Sanchinoside Re;98%byHPLC/CH90650;Re Ginsenoside Re;Ginsenoside Re-RM;Ginsenoside Re (P)
CBNumber:
CB5210824
Molecular Formula:
C48H82O18
Molecular Weight:
947.17
MDL Number:
MFCD00133369
MOL File:
52286-59-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-25 20:17:46

Ginsenoside Re Properties

Melting point 201~203℃
Boiling point 1011.8±65.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
form Solid
pka 12.85±0.70(Predicted)
color White to Off-White
Cosmetics Ingredients Functions HUMECTANT
SKIN CONDITIONING
ANTIOXIDANT
InChIKey PWAOOJDMFUQOKB-WCZZMFLVSA-N
LogP 4.750 (est)
CAS DataBase Reference 52286-59-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 46F3R0BL3I
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  LY9536700
HS Code  29389090
NFPA 704
0
2 0

Ginsenoside Re price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML4125 Ginsenoside Re ≥98% 52286-59-6 10 mg $106 2026-04-30 Buy
Sigma-Aldrich SML4125 Ginsenoside Re ≥98% 52286-59-6 50 mg $320 2026-04-30 Buy
Sigma-Aldrich PHL89212 Ginsenoside Re phyproof? Reference Substance 52286-59-6 10mg $228 2026-04-30 Buy
Sigma-Aldrich 77960 Ginsenoside Re analytical standard 52286-59-6 10mg $165 2026-04-30 Buy
Sigma-Aldrich 03000590 Ginsenoside Re primary pharmaceutical reference standard 52286-59-6 10mg $742 2026-04-30 Buy
Product number Packaging Price Buy
SML4125 10 mg $106 Buy
SML4125 50 mg $320 Buy
PHL89212 10mg $228 Buy
77960 10mg $165 Buy
03000590 10mg $742 Buy

Ginsenoside Re Chemical Properties, Uses, Production

Chemical Properties

White solid

Uses

Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.

Definition

ChEBI: Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent and a nephroprotective agent. It is a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a beta-D-glucoside, a ginsenoside, a tetracyclic triterpenoid, a disaccharide derivative and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

in vivo

Ginsenoside Re reduces insulin resistance in 3T3-L1 adipocytes and high-fat diet (HFD) rats through inhibition of JNK and NF-κB activation[2]. Intraperitoneal injection of lipopolysaccharide (LPS) at a dose of 20 mg/kg is lethal to mice, and 70% to 80% of the mice die within 60 h. However, pretreatment of the mice with Rg1 or Ginsenoside Re increases their survival rates in a dose-dependent manner. With the doses of Rg1 or Ginsenoside Re increase from 2.5 to 5 mg/kg, the survival rate is elevated from 60% to 90% (Rg1) or from 30% to 40% (Ginsenoside Re). All the mice administered Rg1 at a minimal dose of 10 mg/kg are protected from death compared to 80% survival of mice treated with an equal dose of Ginsenoside Re. To protect all the mice, 20 mg/kg Ginsenoside Re is needed. To investigate the anti-inflammatory potential of Rg1 and Ginsenoside Re, 1 mg/kg Rg1 or Ginsenoside Re is injected into rats and then challenged the animals with LPS. The injection procedure itself causes a transient stress-induced increase in body temperature of ~1.2°C in each group. Thereafter, LPS-challenged rats without pretreatment develope a robust biphasic fever, with the first peak reaching ~1.5°C at 2 h and the second peak reaching 1.8°C at 4 h. In contrast, the temperature changes for the Rg1-, Ginsenoside Re-, and TAK-242-treated groups are only 0.9, 1.2, and 0.8°C at 2 h and 1.3, 1.4, and 1.0°C at 4 h, respectively. Pretreatment with Rg1, Ginsenoside Re, or TAK-242 significantly attenuates LPS-induced alterations in body temperature[3].

target

AMPK | TLR | p38MAPK | HO-1 | TNF-α | Potassium Channel | NO | Calcium Channel | ERK | Akt | mTOR | CD4 | Calcium Channel | c-Src | NOS

IC 50

1-40; Aβ1-42; NF-κB; JNK

Ginsenoside Re Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 390)
Supplier Tel Email Country ProdList Advantage
Wuhan Zhongzhicheng Biotechnology Co., Ltd. 13628624121 13628604890 1205052329@qq.com China 9955 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Nanjing Yuanzhi Biotechnology Co. Ltd. 15805159960; 1211550495@qq.com China 1797 58
Nanjing Digger Medical Technology Co. Ltd. 025-025-51191215 18013836722 2399235533@qq.com China 4932 58
Nanjing Spring & Autumn Biological Engineering Co., Ltd. 17388075642 13815430202 sale02@cqherb.com China 261 59
Nanjing bingcheng Biotechnology Co., Ltd. 18805194892 2727751293@qq.com China 172 58
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 18080489829@163.com China 8379 60
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 13186333400 19299362551 cuichengbio@163.com China 1931 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76

Related articles

View Latest Price from Ginsenoside Re manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ginsenoside Re pictures 2026-07-27 Ginsenoside Re
52286-59-6
$43.00-98.00 99.49% 10g TargetMol Chemicals Inc.
Ginsenoside Re pictures 2025-02-13 Ginsenoside Re
52286-59-6
$1.00 1g 98% 1000 Apeloa production Co.,Limited
Ginsenoside Re pictures 2023-02-24 Ginsenoside Re
52286-59-6
5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Ginsenoside Re pictures
  • Ginsenoside Re
    52286-59-6
  • $0.00
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
chikusetsusaponinivc b-D-Glucopyranoside, (3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-(6-deoxy-a-L-mannopyranosyl)- (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside DCR-020 DCR-020;PANAXOSIDE RE;GINSENOSIDE B2;CHIKUSETSUSAPONIN IVC Ginsenoside Re 52286-59-6 ginsenosideb2 GINSENOSIDE GINSENOSIDE-RE GINSENOSIDE RE 2-O-(6-deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside Ginsenoside Re std. 98%byHPLC/CH90650 Panaxoside GINSENOSIDE RE WITH HPLC GINSENOSIDE-RE (GINSENOSIDE B2) NSC 308877 Sanchinoside Re Panaxoside RE, Ginsenoside B2, Chikusetsusaponin IVc glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-(6-deoxy-α-L-mannopyranosyl)- β-D-Glucopyranoside,(3β,6α,12β)-20-(β-D- [20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammar-24-en-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside [20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxydammar-24-en-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammar-24-en-6α-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside ginsenoside-Re standard Ginsenoside Re ,97% β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)- (2S,3R,4R,5R,6S)-2-(((1R,2S,3R,4R,6R)-6-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-((S)-1-hydroxy-5-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hex-4-en-1-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-2,3-dihydroxy-4-(hydroxymethyl)cyclohexyl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cycl (3beta,6alpha,12beta)-20-(beta-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-6-Deoxy-alpha-L-mannopyranosyl-beta-D-glucopyranoside (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol 4-?Dihydroxyphenyl)?ethanone Ginsenoside Re (P) (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-Dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol Re Ginsenoside Re Ginsenoside Re(AS) Ginsenoside Re-RM β-?D-?Glucopyranoside, (3β,?6α,?12β)?-?20-?(β-?D-?glucopyranosyloxy)?-?3,?12-?dihydroxydammar-?24-?en-?6-?yl 2-?O-?(6-?deoxy-?α-?L-?mannopyranosyl)?- 52286-59-6 197-70-5 C48H82O18 Inhibitors Ginsenoside series chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract The group of Ginsenosides Saponins