BOC-THR(ME)-OH
- CAS No.
- 48068-25-3
- Chemical Name:
- BOC-THR(ME)-OH
- Synonyms
- BOC-THR(ME);BOC-THR(ME)-OH;Boc-L-Thr(Me)-OH;BOC-O-METHYL-L-THREONINE;BOC-THR(ME)-OH USP/EP/BP;N-Boc-O-Methyl-L-threonine;N-Boc-O-methyl-L-threonine,95%;(Tert-Butoxy)Carbonyl Thr(Me)-OH;O-Methyl-L-threonine, N-BOC protected;N-(tert-butoxycarbonyl)-O-methyl-L-threonine
- CBNumber:
- CB3748587
- Molecular Formula:
- C10H19NO5
- Molecular Weight:
- 233.26
- MDL Number:
- MFCD00076990
- MOL File:
- 48068-25-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Boc-O-Methyl-L-threonine | B657418 | 50mg | $60 |
| Boc-O-methyl-L-threonine | 236634 | 250mg | $237 |
| O-Methyl-L-threonine, N-Boc protected | 4156-1-W1 | 25g | $245 |
| Boc-O-Methyl-L-threonine 96+% | AS33266 | 25g | $328 |
| O-Methyl-L-threonine,N-BOCprotected 98% | OR61332 | 1g | $28 |
| More product size | |||
| Boiling point | 362.1±37.0 °C(Predicted) |
|---|---|
| Density | 1.123±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Solid |
| pka | 3.50±0.10(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C10H19NO5/c1-6(15-5)7(8(12)13)11-9(14)16-10(2,3)4/h6-7H,1-5H3,(H,11,14)(H,12,13)/t6-,7+/m1/s1 |
| InChIKey | VWSUOKFUIPMDDX-RQJHMYQMSA-N |
| SMILES | C(O)(=O)[C@H]([C@H](OC)C)NC(OC(C)(C)C)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501 | |||||||||
| HS Code | 2922500090 | |||||||||
| NFPA 704 |
|
BOC-THR(ME)-OH price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B657418 | Boc-O-Methyl-L-threonine | 48068-25-3 | 50mg | $60 | 2021-12-16 | Buy |
| Usbiological | 236634 | Boc-O-methyl-L-threonine | 48068-25-3 | 250mg | $237 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4156-1-W1 | O-Methyl-L-threonine, N-Boc protected | 48068-25-3 | 25g | $245 | 2021-12-16 | Buy |
| Activate Scientific | AS33266 | Boc-O-Methyl-L-threonine 96+% | 48068-25-3 | 25g | $328 | 2021-12-16 | Buy |
| Apolloscientific | OR61332 | O-Methyl-L-threonine,N-BOCprotected 98% | 48068-25-3 | 1g | $28 | 2021-12-16 | Buy |
BOC-THR(ME)-OH Chemical Properties,Uses,Production
Uses
Boc-Thr(Me)-OH is a threonine derivative[1].
Synthesis
4144-02-9
24424-99-5
48068-25-3
GENERAL METHOD: O-Methyl-L-threonine (10 g, 75.11 mmol) was dissolved in a solvent mixture of THF (350 mL) and water (350 mL) and cooled to 0 °C. NaHCO3 (18.93 g, 225.32 mmol) and di-tert-butyl dicarbonate (Boc2O, 24.59 g, 112.66 mmol) were added sequentially, and the reaction mixture was gradually warmed to room temperature and stirred for 18 hours. Upon completion of the reaction, the pH was adjusted to 4 with aqueous KHSO4 to quench the reaction, followed by extraction with EtOAc (5 × 150 mL). The organic layers were combined, dried with Na2SO4 and concentrated under reduced pressure. The residue was ground with heptane to afford (2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutyric acid as a white solid (16.50 g, 94% yield).1H NMR (400 MHz, CDCl3): δ 1.22 (d, 3H), 1.45 (s, 9H), 3.28 (s, 3H), 3.98 (br d, 1H). 4.38 (d, 1H), 5.28 (d, 1H), 10.40-10.60 (br s, 1H).
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
BOC-THR(ME)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from BOC-THR(ME)-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-06 | Boc-Thr(me)-OH
48068-25-3
|
US $1.00 / g | 1g | 98% | 100KG | Sichuan Jiaying Lai Technology Co.,LTD | |
 |
2019-12-24 | BOC-THR(ME)-OH
48068-25-3
|
US $1.00 / g | 100g | 98%min | G/KG/T | Career Henan Chemical Co |
-
- Boc-Thr(me)-OH
48068-25-3
- US $1.00 / g
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD
-
- BOC-THR(ME)-OH
48068-25-3
- US $1.00 / g
- 98%min
- Career Henan Chemical Co
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