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BOC-THR(ME)-OH

CAS No.
48068-25-3
Chemical Name:
BOC-THR(ME)-OH
Synonyms
N-(tert-butoxycarbonyl)-O-methyl-L-threonine;Boc-L-Thr(Me)-OH;BOC-THR(ME);BOC-THR(ME)-OH;BOC-O-METHYL-L-THREONINE;BOC-THR(ME)-OH USP/EP/BP;N-Boc-O-Methyl-L-threonine;N-Boc-O-methyl-L-threonine,95%;(Tert-Butoxy)Carbonyl Thr(Me)-OH;O-Methyl-L-threonine, N-BOC protected
CBNumber:
CB3748587
Molecular Formula:
C10H19NO5
Molecular Weight:
233.26
MDL Number:
MFCD00076990
MOL File:
48068-25-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:13:53
Product description Number Pack Size Price
Boc-O-methyl-L-threonine Asreported 265268 500mg $375
Boc-O-methyl-L-threonine Asreported 265268 1g $635
Boc-O-methyl-L-threonine Asreported 265268 2g $895
Boc-O-methyl-L-threonine Asreported 265268 5g $1559
Boc-O-methyl-L-threonine Asreported 265268 10g $2289
More product size

BOC-THR(ME)-OH Properties

Boiling point 362.1±37.0 °C(Predicted)
Density 1.123±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 3.50±0.10(Predicted)
form Solid
color White to off-white
InChI InChI=1S/C10H19NO5/c1-6(15-5)7(8(12)13)11-9(14)16-10(2,3)4/h6-7H,1-5H3,(H,11,14)(H,12,13)/t6-,7+/m1/s1
InChIKey VWSUOKFUIPMDDX-RQJHMYQMSA-N
SMILES C(O)(=O)[C@H]([C@H](OC)C)NC(OC(C)(C)C)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
HS Code  2922500090
NFPA 704
1
0 0

BOC-THR(ME)-OH price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 265268 Boc-O-methyl-L-threonine Asreported 48068-25-3 500mg $375 2026-06-03 Buy
Usbiological 265268 Boc-O-methyl-L-threonine Asreported 48068-25-3 1g $635 2026-06-03 Buy
Usbiological 265268 Boc-O-methyl-L-threonine Asreported 48068-25-3 2g $895 2026-06-03 Buy
Usbiological 265268 Boc-O-methyl-L-threonine Asreported 48068-25-3 5g $1559 2026-06-03 Buy
Usbiological 265268 Boc-O-methyl-L-threonine Asreported 48068-25-3 10g $2289 2026-06-03 Buy
Product number Packaging Price Buy
265268 500mg $375 Buy
265268 1g $635 Buy
265268 2g $895 Buy
265268 5g $1559 Buy
265268 10g $2289 Buy

BOC-THR(ME)-OH Chemical Properties,Uses,Production

Uses

Boc-Thr(Me)-OH is a threonine derivative[1].

Synthesis

O-METHYL-L-THREONINE

4144-02-9

Di-tert-butyl dicarbonate

24424-99-5

BOC-THR(ME)-OH

48068-25-3

GENERAL METHOD: O-Methyl-L-threonine (10 g, 75.11 mmol) was dissolved in a solvent mixture of THF (350 mL) and water (350 mL) and cooled to 0 °C. NaHCO3 (18.93 g, 225.32 mmol) and di-tert-butyl dicarbonate (Boc2O, 24.59 g, 112.66 mmol) were added sequentially, and the reaction mixture was gradually warmed to room temperature and stirred for 18 hours. Upon completion of the reaction, the pH was adjusted to 4 with aqueous KHSO4 to quench the reaction, followed by extraction with EtOAc (5 × 150 mL). The organic layers were combined, dried with Na2SO4 and concentrated under reduced pressure. The residue was ground with heptane to afford (2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutyric acid as a white solid (16.50 g, 94% yield).1H NMR (400 MHz, CDCl3): δ 1.22 (d, 3H), 1.45 (s, 9H), 3.28 (s, 3H), 3.98 (br d, 1H). 4.38 (d, 1H), 5.28 (d, 1H), 10.40-10.60 (br s, 1H).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

BOC-THR(ME)-OH Preparation Products And Raw materials

Global( 132)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Hefei Hangang Pharmaceutical Technology Co., Ltd.
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Hefei TNJ Chemical Industry Co.,Ltd.
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GIHI CHEMICALS CO.,LIMITED
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Sichuan HongRi Pharma-Tech Co.,Ltd
+86-15680023009 ni@enlaibio.com China 1103 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58

View Lastest Price from BOC-THR(ME)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Thr(me)-OH pictures 2020-01-06 Boc-Thr(me)-OH
48068-25-3
$1.00 1g 98% 100KG Sichuan Jiaying Lai Technology Co.,LTD
BOC-THR(ME)-OH pictures 2019-12-24 BOC-THR(ME)-OH
48068-25-3
$1.00 100g 98%min Career Henan Chemical Co
  • Boc-Thr(me)-OH pictures
  • Boc-Thr(me)-OH
    48068-25-3
  • $1.00
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD
BOC-THR(ME)-OH BOC-O-METHYL-L-THREONINE (2S,3R)-2-(tert-butoxycarbonylamino)-3-methoxybutanoic acid O-Methyl-L-threonine, N-BOC protected BOC-THR(ME) (Tert-Butoxy)Carbonyl Thr(Me)-OH (2S,3R)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-THREONINE N-Boc-O-Methyl-L-threonine L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl- N-Boc-O-methyl-L-threonine,95% BOC-THR(ME)-OH USP/EP/BP N-[(1,1-Dimethylethoxy)carbonyl]-O-methyl-L-threonine Boc-L-Thr(Me)-OH N-(tert-butoxycarbonyl)-O-methyl-L-threonine 48068-25-3