7-Chloroquinoline
- CAS No.
- 612-61-3
- Chemical Name:
- 7-Chloroquinoline
- Synonyms
- 7-Chloro-4-nitroquinoline;7-Chloroquinoline;Quinoline, 7-chloro-;7-Chloro-1-azanaphthalene;7-Chloroquinoline,97%,SS-5262
- CBNumber:
- CB3758353
- Molecular Formula:
- C9H6ClN
- Molecular Weight:
- 163.6
- MDL Number:
- MFCD00956370
- MOL File:
- 612-61-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 31.5°C |
|---|---|
| Boiling point | 268°C(lit.) |
| Density | 1.2158 |
| refractive index | 1.6108 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Acetone (Slightly), Chloroform (Slightly) |
| pka | 3.36±0.14(Predicted) |
| form | Solid |
| color | Tan |
| λmax | 319nm(EtOH aq.)(lit.) |
| InChI | 1S/C9H6ClN/c10-8-4-3-7-2-1-5-11-9(7)6-8/h1-6H |
| InChIKey | QNGUPQRODVPRDC-UHFFFAOYSA-N |
| SMILES | Clc1ccc2cccnc2c1 |
| NIST Chemistry Reference | 7-chloroquinoline(612-61-3) |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P271-P280 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 2933499090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
7-Chloroquinoline price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS014905 | 7-chloroquinoline AldrichCPR | 612-61-3 | 100 mg | $77.9 | 2026-04-30 | Buy |
| TCI Chemical | C3085 | 7-Chloroquinoline >98.0%(GC) | 612-61-3 | 5g | $187 | 2026-04-30 | Buy |
| TCI Chemical | C3085 | 7-Chloroquinoline >98.0%(GC) | 612-61-3 | 25g | $561 | 2026-04-30 | Buy |
| Usbiological | 269508 | 7-Chloroquinoline Asreported | 612-61-3 | 1g | $360 | 2026-06-03 | Buy |
| Usbiological | 269508 | 7-Chloroquinoline Asreported | 612-61-3 | 2g | $505 | 2026-06-03 | Buy |
7-Chloroquinoline Chemical Properties, Uses, Production
Chemical Properties
light yellow powder
Uses
Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates.
Synthesis
86-98-6
612-61-3
General Program 138: Synthesis of 7-chloroquinoline (Intermediate 573) 1. 4,7-Dichloroquinoline (10 g, 50 mmol) was dissolved in THF (100 ml) and degassed using N2 for 5 min. 2. PdCl2 (dppf) (1.2 g, 2 mmol), TMEDA (9.97 g, 86 mmol) and NaBH4 (3.24 g, 86 mmol) were added sequentially. 3. The reaction mixture was stirred at room temperature for 5 hours. 4. Upon completion of the reaction, brine (20 ml) was added dropwise followed by removal of solvent under vacuum. 5. The residue was dissolved in EtOAc (200 ml), dried by adding MgSO4 and then concentrated under vacuum. 6. The crude product was purified by column chromatography using heptane/EtOAc (4:1 to 1:1 gradient) as eluent to afford the title compound 7-chloroquinoline (5.4 g, 65% yield). MW: 163.61 HPLCMS (Method B): [m/z]: 163.90
References
[1] Tetrahedron Letters, 2010, vol. 51, # 12, p. 1562 - 1565
[2] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209
[3] Patent: US2012/214803, 2012, A1. Location in patent: Page/Page column 185
7-Chloroquinoline Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
View Latest Price from 7-Chloroquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 7-CHLOROQUINOLINE
612-61-3
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-04-04 | 7-CHLOROQUINOLINE
612-61-3
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | 7-CHLOROQUINOLINE
612-61-3
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- 7-CHLOROQUINOLINE
612-61-3
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 7-CHLOROQUINOLINE
612-61-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 7-CHLOROQUINOLINE
612-61-3
- $1.00
- 98%
- Career Henan Chemical Co
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