Mepacrine hydrochloride
- CAS No.
- 6151-30-0
- Chemical Name:
- Mepacrine hydrochloride
- Synonyms
- mepacrinehcl;hloride2h2-o;QuinacrineHCl;AtabrineMepacnine;ochloride,dihydrate;Mipalin hydrochloride;Quinacrinehydrochlorid;Mepacrine hydrochloride;QUINACRINE,ATABRINE MEPACNINE;atabrinehydrochloridedihydrate
- CBNumber:
- CB4138653
- Molecular Formula:
- C23H36Cl3N3O3
- Molecular Weight:
- 508.91
- MDL Number:
- MFCD00150069
- MOL File:
- 6151-30-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 247 °C |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO: 10 mg/mL (19.65 mM);; |
| form | Solid |
| color | Light yellow to yellow |
| Water Solubility | 2.8 g/100 mL |
| CAS DataBase Reference | 6151-30-0(CAS DataBase Reference) |
| FDA UNII | G6242H2NAA |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| NFPA 704 |
|
Mepacrine hydrochloride price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0027605 | Quinacrine hydrochloride hydrate 98.18% | 6151-30-0 | 100mg | $54 | 2026-06-04 | Buy |
| ApexBio Technology | C5039 | Quinacrine (hydrochloride hydrate) | 6151-30-0 | 100mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | C5039 | Quinacrine (hydrochloride hydrate) | 6151-30-0 | 500mg | $60 | 2026-05-06 | Buy |
| ApexBio Technology | C5039 | Quinacrine (hydrochloride hydrate) | 6151-30-0 | 1g | $80 | 2026-05-06 | Buy |
| ApexBio Technology | C5039 | Quinacrine (hydrochloride hydrate) | 6151-30-0 | 5g | $135 | 2026-05-06 | Buy |
Mepacrine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
bright yellow powder
Uses
Quinacrine Dihydrochloride Dihydrate is a phophoslipase A2 inhibitor.
General Description
Qunacrine is no longer available in theUnited States. It can be considered one of the most toxic ofthe antimalarial drugs even though, at one time, it was commonlyused. It acts at many sites within the cell includingintercalation of DNA strands, succinic dehydrogenase andmitochondrial electron transport, and cholinesterase. It maybe tumorgenic and mutagenic and has been used as a sclerosingagent. Because it is an acridine dye, quinacrine cancause yellow discoloration of the skin and urine.
in vivo
Quinacrine (100 mg/kg three times per week for two consecutive weeks) significantly suppresses circulating blast cells at days 30/31 and increases the median survival time (MST). Quinacrine does not decrease the body weight of treated animals at the tested dose[2].
| Animal Model: | Female SCID mice with acute myeloid leukemia (AML)-PS model[2] |
| Dosage: | 100 mg/kg |
| Administration: | Administered by oral gavage (po); three times a week for two consecutive weeks |
| Result: | In the first AML mouse in vivo study, evaluation of circulating leukemic cells detected in blood samples (in percent of white blood cells (WBC)) at day 30/31 showed 72% human tumor cells in the control mice, whereas in mice treated with Quinacrine, this was only 2.2%. The MST of control mice was 34 days whereas it was 46 days in Quinacrine-treated mice. |
IC 50
Plasmodium
Mepacrine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Mepacrine hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 | |
| AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4875 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Nanjing crow LuNing pharmaceutical technology co., LTD | 13382066392 | CHINA | 4851 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9389 | 58 |
View Lastest Price from Mepacrine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Mepacrine hydrochloride USP/EP/BP
6151-30-0
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-04-28 | Mepacrine hydrochloride
6151-30-0
|
1KG | 99.0% | 500 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-07-10 | Mepacrine hydrochloride
6151-30-0
|
$8.80 | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-
- Mepacrine hydrochloride USP/EP/BP
6151-30-0
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Mepacrine hydrochloride
6151-30-0
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Mepacrine hydrochloride
6151-30-0
- $8.80
- 97%-99%
- Career Henan Chemical Co
