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2-Chloro-5-trifluoromethylbenzaldehyde

2-Chloro-5-trifluoromethylbenzaldehyde Structure
2-Chloro-5-trifluoromethylbenzaldehyde structure
CAS No.
82386-89-8
Chemical Name:
2-Chloro-5-trifluoromethylbenzaldehyde
Synonyms
2-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE;TIMTEC-BB SBB003466;2-Chloro-5-trifluoromethylb;4-Chloro-3-formylbenzotrifluoride;2-Chloro-5-(trifluoromethyl)benzaldehyde98%;Benzaldehyde, 2-chloro-5-(trifluoromethyl)-;2-Chloro-5-(trifluoromethyl)benzaldehyde >2-Chloro-5-(trifluoroMethyl)benzaldehyde, 95+%;2-Chloro-5-(trifluoromethyl)benzaldehyde, 97+%;4-Chloro-3-formylbenzotrifluoride, 6-Chloro-alpha,alpha,alpha-trifluoro-m-tolualdehyde
CBNumber:
CB3759178
Molecular Formula:
C8H4ClF3O
Molecular Weight:
208.57
MDL Number:
MFCD00134430
MOL File:
82386-89-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:19:44
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2-Chloro-5-trifluoromethylbenzaldehyde Properties

Boiling point 42-44 °C1.5 mm Hg(lit.)
Density 1.435 g/mL at 25 °C(lit.)
refractive index n20/D 1.488(lit.)
Flash point 193 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
color White to Yellow to Green
Specific Gravity 1.435
Sensitive Air Sensitive
InChI 1S/C8H4ClF3O/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-4H
InChIKey OZZOJJJYKYKBNH-UHFFFAOYSA-N
SMILES FC(F)(F)c1ccc(Cl)c(C=O)c1
CAS DataBase Reference 82386-89-8(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
RIDADR  NA 1993 / PGIII
WGK Germany  3
HazardClass  IRRITANT
HS Code  29130000
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 1

2-Chloro-5-trifluoromethylbenzaldehyde price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 376825 2-Chloro-5-(trifluoromethyl)benzaldehyde 98% 82386-89-8 5g $62.9 2026-04-30 Buy
TCI Chemical C2047 2-Chloro-5-(trifluoromethyl)benzaldehyde >95.0%(GC) 82386-89-8 5g $68 2026-04-30 Buy
TCI Chemical C2047 2-Chloro-5-(trifluoromethyl)benzaldehyde >95.0%(GC) 82386-89-8 25g $286 2026-04-30 Buy
Biosynth FC64009 2-Chloro-5-(trifluoromethyl)benzaldehyde 82386-89-8 25g $150 2026-06-04 Buy
Biosynth FC64009 2-Chloro-5-(trifluoromethyl)benzaldehyde 82386-89-8 10g $150 2026-06-04 Buy
Product number Packaging Price Buy
376825 5g $62.9 Buy
C2047 5g $68 Buy
C2047 25g $286 Buy
FC64009 25g $150 Buy
FC64009 10g $150 Buy

2-Chloro-5-trifluoromethylbenzaldehyde Chemical Properties, Uses, Production

Chemical Properties

Colorless liquid

Uses

2-Chloro-5-(trifluoromethyl)benzaldehyde may be used as reactant in the three-component reaction of 2-halogenated aromatic aldehydes, 1H-benzo[d]imidazol-5-amine and cyclohexane-1,3-diones to afford imidazoquinolinoacridinone derivatives. It may be used in the gas-phase chemical derivatization of poly(tetrafluoroethylene) and poly(ethylene terephthalate) using gas plasma.

Synthesis

2-Chloro-5-(trifluoromethyl)benzyl alcohol

64372-62-9

2-Chloro-5-trifluoromethylbenzaldehyde

82386-89-8

General procedure for the synthesis of 2-chloro-5-trifluoromethylbenzaldehyde from 2-chloro-5-trifluoromethylbenzyl alcohol: 2-chloro-5-trifluoromethylbenzyl alcohol (5.0 mmol), copper acetate (Cu(OAc)2, 9.1 mg, 0.05 mmol), and 2,2,6,6-tetramethylpiperidinium-1-oxyl radical (TEMPO, 7.8 mg, 0.05 mmol ) in a solvent mixture of acetonitrile (CH3CN, 5 mL) and water (H2O, 10 mL) was stirred at room temperature for the reaction. The reaction process was monitored by thin-layer chromatography (TLC) and the eluent was petroleum ether/ethyl acetate (4:1). After completion of the reaction, dichloromethane (10 mL) was added to the reaction mixture for extraction. The organic phase was separated and the aqueous phase was extracted twice more with dichloromethane (10 mL x 2). All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to obtain the crude product. The crude product was purified by column chromatography with the eluent of petroleum ether/ethyl acetate (10:1) to obtain the target product 2-chloro-5-trifluoromethylbenzaldehyde.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 10, p. 1677 - 1681
[2] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983

2-Chloro-5-trifluoromethylbenzaldehyde Preparation Products And Raw materials

Raw materials

2-Chloro-5-(trifluoromethyl)benzyl alcohol Acetonitrile Copper(II) acetate TEMPO

Preparation Products

2-Chloro-5-trifluoromethylbenzaldehyde Suppliers

Global Suppliers ( 249)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Ark Pharm, Inc. 56
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64

View Latest Price from 2-Chloro-5-trifluoromethylbenzaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-trifluoromethylbenzaldehyde pictures 2026-03-20 2-Chloro-5-trifluoromethylbenzaldehyde
82386-89-8
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Chloro-5-trifluoromethylbenzaldehyde pictures 2026-02-02 2-Chloro-5-trifluoromethylbenzaldehyde
82386-89-8
 10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2-Chloro-5-trifluoromethylbenzaldehyde pictures 2024-04-25 2-Chloro-5-trifluoromethylbenzaldehyde
82386-89-8
 $30.00-100.00 1kg 99.93% 1000kg per week Ouhuang Engineering Materials (Hubei) Co., Ltd

2-Chloro-5-trifluoromethylbenzaldehyde Spectrum

2-Chloro-5-trifluoromethylbenzaldehyde(82386-89-8)1HNMR2-Chloro-5-trifluoromethylbenzaldehyde(82386-89-8)Raman2-Chloro-5-trifluoromethylbenzaldehyde(82386-89-8)IR

82386-89-8 (2-Chloro-5-trifluoromethylbenzaldehyde) Related Search:

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TIMTEC-BB SBB003466 2-Chloro-5-trifluoromethylb 2-Chloro-5-(trifluoromethyl)benzaldehyde, 97+% 2-Chloro-5-(trifluoromethyl)benzaldehyde98% 4-Chloro-3-formylbenzotrifluoride, 6-Chloro-alpha,alpha,alpha-trifluoro-m-tolualdehyde 4-Chloro-3-formylbenzotrifluoride 2-Chloro-5-(trifluoroMethyl)benzaldehyde, 95+% 2-Chloro-5-(trifluoromethyl)benzaldehyde > Benzaldehyde, 2-chloro-5-(trifluoromethyl)- 2-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE 82386-89-8 2386-89-8 C8H4OClF3 Building Blocks C8 Carbonyl Compounds ALDEHYDE Aldehydes Organic Building Blocks Fluorine series Benzaldehyde Aldehydes C8 Carbonyl Compounds Fluorobenzene Carbonyl Compounds