Methyl 2-bromomethyl-5-chloro-benzoate
- CAS No.
- 668262-52-0
- Chemical Name:
- Methyl 2-bromomethyl-5-chloro-benzoate
- Synonyms
- -5-chlorobenzoate;2-(bromethyl)-5-chloromethyl benzoate;Methyl 2-bromomethyl-5-chloro-benzoate;2-BROMOMETHYL-5-CHLORO-BENZOIC ACID METHYL ESTER;2-carboxy-4-chloro-broMoMethylbenzene Methyl ester;Benzoic acid, 2-(bromomethyl)-5-chloro-, methyl ester
- CBNumber:
- CB3762945
- Molecular Formula:
- C9H8BrClO2
- Molecular Weight:
- 263.52
- MDL Number:
- MFCD06804577
- MOL File:
- 668262-52-0.mol
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P312 |
| HS Code | 2916310090 |
Methyl 2-bromomethyl-5-chloro-benzoate price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 284092 | Methyl 2-bromomethyl-5-chlorobenzoate Asreported | 668262-52-0 | 25mg | $333 | 2026-06-03 | Buy |
| Usbiological | 284092 | Methyl 2-bromomethyl-5-chlorobenzoate Asreported | 668262-52-0 | 50mg | $483 | 2026-06-03 | Buy |
| Usbiological | 284092 | Methyl 2-bromomethyl-5-chlorobenzoate Asreported | 668262-52-0 | 100mg | $652 | 2026-06-03 | Buy |
| Usbiological | 284092 | Methyl 2-bromomethyl-5-chlorobenzoate Asreported | 668262-52-0 | 250mg | $785 | 2026-06-03 | Buy |
| Usbiological | 284092 | Methyl 2-bromomethyl-5-chlorobenzoate Asreported | 668262-52-0 | 500mg | $1055 | 2026-06-03 | Buy |
Methyl 2-bromomethyl-5-chloro-benzoate Chemical Properties, Uses, Production
Synthesis
99585-13-4
668262-52-0
General procedure for the synthesis of methyl 2-(bromomethyl)-5-chlorobenzoate from methyl 2-methyl-5-chlorobenzoate: methyl 5-chloro-2-methylbenzoate (10.0 g, 54 mmol), N-bromosuccinimide (NBS, 10.6 g, 59.5 mmol), and azobisisobutyronitrile (AIBN, 200 mg) were dissolved in 1,2-dichloroethane ( 300 mL). The reaction mixture was irradiated and stirred for 2 h under photocatalytic conditions using [PHOTOLAMP]. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with heptane/dichloromethane as eluent (gradient elution: 9:1, 4:1, 1:1) to afford 11.8 g of methyl 2-(bromomethyl)-5-chlorobenzoate (83% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 7.98 (d, J = 2.1 Hz, 1H), 7.49 (dd, J = 2.2, 8.2 Hz, 1H), 7.43 (d, J = 8.2 Hz, 1H), 4.93 (s, 2H), 3.97 (s, 3H).
References
[1] Patent: WO2004/18414, 2004, A2. Location in patent: Page 112
[2] Patent: WO2005/21508, 2005, A1. Location in patent: Page/Page column 148
[3] Israel Journal of Chemistry, 1971, vol. 9, p. 111 - 118
[4] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 5, p. 1628 - 1631
[5] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 1, p. 360 - 365
Methyl 2-bromomethyl-5-chloro-benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Sheepchem Co., Ltd. | +86 (21) 6715-7650 | sheepchem@163.com | China | 993 | 60 |
| Runpharm Technology Limited | 18171398856 2968382473 | service@runpharm.com | China | 716 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1995 | 58 |
| Shanghai Leto Pharmatech Co.,Ltd. | 86-021-5821 5861; 18016401466 | sales@letopharm.com | China | 235 | 58 |
| Wuhan Chemduro Pharm Tech Co. Ltd. | 18040571231/1402788087 | China | 1972 | 58 | |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 4986 | 50 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| DebyeTec.com Inc. | 18086626237 18086626237 | 2693528373@qq.com | China | 2934 | 56 |
View Latest Price from Methyl 2-bromomethyl-5-chloro-benzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | Methyl 2-(bromomethyl)-5-chlorobenzoate
668262-52-0
|
$1.00 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Methyl 2-(bromomethyl)-5-chlorobenzoate
668262-52-0
- $1.00
- ≥98%
- Career Henan Chemical Co
