4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
- CAS No.
- 138564-60-0
- Chemical Name:
- 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
- Synonyms
- 2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-aMine hydrochloride;3-b][1;OlanzaMine;Olanzapine-5;TIMTEC-BB SBB001030;Olanzapin Imp. Pin 3;5] benzodiazapine HCl;Olanzapine Impurity 5;Olanzapine Impurity L;Olanzapine Impurity 16
- CBNumber:
- CB3770500
- Molecular Formula:
- C12H12ClN3S
- Molecular Weight:
- 265.76
- MDL Number:
- MFCD03085920
- MOL File:
- 138564-60-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 283-285°C |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Sparingly, Sonicated) |
| form | Solid |
| color | Yellow to Dark Beige |
| InChI | InChI=1S/C12H11N3S.ClH/c1-7-6-8-11(13)14-9-4-2-3-5-10(9)15-12(8)16-7;/h2-6,15H,1H3,(H2,13,14);1H |
| InChIKey | FDWMAKNNNPSUTL-UHFFFAOYSA-N |
| SMILES | C12SC(C)=CC=1C(N)=NC1=CC=CC=C1N2.Cl |
| CAS DataBase Reference | 138564-60-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 2933998090 |
| REACH Registrations | Active |
4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FA17460 | Olanzapine hydrochloride | 138564-60-0 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FA17460 | Olanzapine hydrochloride | 138564-60-0 | 2g | $150 | 2026-06-04 | Buy |
| Biosynth | FA17460 | Olanzapine hydrochloride | 138564-60-0 | 10g | $159.2 | 2026-06-04 | Buy |
| Apolloscientific | OR61175 | 4-Amino-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine hydrochloride 95% | 138564-60-0 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR61175 | 4-Amino-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine hydrochloride 95% | 138564-60-0 | 1g | $24 | 2026-06-04 | Buy |
4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Chemical Properties, Uses, Production
Synthesis
In a 500 mL round-bottom flask equipped with a mechanical stirrer and thermometer, 10.0 g (0.0386 mol) of 5-methyl-2-((2-nitrobenzene)amino)thiophene-3-carboxynitrile (1) and 100 mL of ethanol were added. Then 7.4 g (0.062 mol) of tin powder and 84 mL of 4M hydrochloric acid were added, and the mixture was stirred at 50 °C for 0.5 h. The temperature of the reaction mixture was raised to 85 °C, and stirring was continued for 4 h. The mixture was then cooled to 25 °C and stirred for another 8 h, which resulted in the precipitation of a solid. The precipitated crystals were collected, washed with 20 mL of ethanol, and dried under vacuum. 9.8 g (96%) of 2-methyl-2-(nitrobenzene) ...
![Synthetic route of 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Synthetic route of 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride](https://www.chemicalbook.com/NewsImg/2022-10-08/6380081821409211462375084.jpg)
Chemical Properties
Yellow Crystaline solid
Uses
Intermediate in the preparation of Olanzapine (O253750).
4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Fanlai Biomedical Technology Co., Ltd. | 17080805366 | 17080805366@126.com | China | 42 | 58 |
| Suzhou Junch Pharmaceutical Co., Ltd | 18625279558; 18625279558 | sales01@junchpharm.com | China | 12 | 58 |
| Pushan Industry (Shaanxi) Co., Ltd. | 029-81310890 18165209495 | 2929288192@qq.com | China | 9949 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Latest Price from 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
138564-60-0
|
$2.00-8.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2026-08-30 | Olanzapine impurity L HCl
138564-60-0
|
$29.00 | 99.93% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2026-08-20 | 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
138564-60-0
|
$1.10 | 1g | 99.0% Min | 100 Tons | Dideu Industries Group Limited |
-
![4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride pictures](/ProductImageEN/2024-04/Small/85a38de6-5bfa-44f4-b748-261deca880af.gif)
- 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
138564-60-0
- $2.00-8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- Olanzapine impurity L HCl
138564-60-0
- $29.00
- 99.93%
- TargetMol Chemicals Inc.
-
![4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride pictures](/ProductImageEN/2022-05/Small/83d11be5-d203-49cf-83fc-5fb3330c0eb1.jpg)
- 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
138564-60-0
- $1.10
- 99.0% Min
- Dideu Industries Group Limited
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