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1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one Structure
1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one structure
CAS No.
1481-02-3
Chemical Name:
1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one
Synonyms
2-METHYL-5-(TRIFLUOROMETHYL)-2,4-DIHYDRO-3H-PYRAZOL-3-ONE;BUTTPARK 24\09-48;METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE;3-trifluoromethyl-1-methyl-1H-5-Pyrazolone;1-Methyl-3-trifluormethyl-2-pyrazolin-5-one;1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one;2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one;1-Methyl-3-(trifluoroMethyl)-1H-pyrazol-5(4H)-one;1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one97%;1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one 97%
CBNumber:
CB3772867
Molecular Formula:
C5H5F3N2O
Molecular Weight:
166.1
MDL Number:
MFCD00051654
MOL File:
1481-02-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:12
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1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one Properties

Melting point 178 °C
Boiling point 101.6±50.0 °C(Predicted)
Density 1.50±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 0.58±0.50(Predicted)
Appearance White to off-white Solid
BRN 5811070
CAS DataBase Reference 1481-02-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P312-P305+P351+P338-P362-P403+P233-P501
Hazard Codes  Xi,T
Risk Statements  25
Safety Statements  45
Hazard Note  Irritant
HS Code  2933119000
NFPA 704
1
2 0

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FD95055 2,4-Dihydro-2-Methyl-5-(Trifluoromethyl)-3H-Pyrazol-3-One 1481-02-3 1g $150 2026-06-04 Buy
Biosynth FD95055 2,4-Dihydro-2-Methyl-5-(Trifluoromethyl)-3H-Pyrazol-3-One 1481-02-3 5g $414.15 2026-06-04 Buy
Biosynth FD95055 2,4-Dihydro-2-Methyl-5-(Trifluoromethyl)-3H-Pyrazol-3-One 1481-02-3 10g $662.6 2026-06-04 Buy
Apolloscientific PC3274 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one 95 1481-02-3 1g $52 2026-06-04 Buy
Apolloscientific PC3274 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one 95 1481-02-3 5g $55 2026-06-04 Buy
Product number Packaging Price Buy
FD95055 1g $150 Buy
FD95055 5g $414.15 Buy
FD95055 10g $662.6 Buy
PC3274 1g $52 Buy
PC3274 5g $55 Buy

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one Chemical Properties, Uses, Production

Synthesis

Ethyl 4,4,4-trifluoroacetoacetate

372-31-6

Methylhydrazine

60-34-4

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE

1481-02-3

0.1 mL of methylhydrazine and 10 mL of anhydrous ethanol were added to a 250 mL three-necked flask, stirred and heated to 50°C. Subsequently, 0.1 mol of ethyl trifluoroacetoacetate was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the mixture was cooled to promote crystallization. The resulting yellow solid was collected by vacuum filtration and dried. The yield of the final product was 85.8%.

References

[1] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0091; 0092; 0093
[2] Australian Journal of Chemistry, 2010, vol. 63, # 5, p. 785 - 791

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one synthesis

372-31-6
60-34-4
1481-02-3
Synthesis of 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one from Ethyl 4,4,4-trifluoroacetoacetate and Methylhydrazine

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one Preparation Products And Raw materials

Raw materials

Methyl 4,4,4-trifluoroacetoacetate Methylhydrazine Ethyl 4,4,4-trifluoroacetoacetate

Preparation Products

5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one Suppliers

Global Suppliers ( 52)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 6746 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Supplier Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
Energy Chemical 61
China DongFan Chemical Co.,LTD 66
Syntechem Co.,Ltd 57
Sinopharm Chemical Reagent Co,Ltd. 79
Cochemical Ltd. 58
Amadis Chemical Company Limited 58
Cochemical Ltd. 58
Aikon International Limited 58

1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one Spectrum

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE(1481-02-3)1HNMR

1481-02-3 (1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one) Related Search:

1-Phenyl-3-(trifluoromethyl)-2-pyrazolin-5-one 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 3-(Trifluoromethyl)-2-pyrazolin-5-one 2-Pyrrolidinone BUTTPARK 17\04-73
BUTTPARK 17\04-75 BUTTPARK 17\04-72 4-[(3-Chloroanilino)methylene]-2-phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one Methyl 2-(([5-oxo-1-phenyl-3-(trifluoromethyl)-1,5-dihydro-4H-pyrazol-4-yliden]methyl)amino)acetate 2-Phenyl-5-(trifluoromethyl)-4-([2-(trifluoromethyl)anilino]methylene)-2,4-dihydro-3H-pyrazol-3-one
2-Phenyl-5-(trifluoromethyl)-4-([3-(trifluoromethyl)anilino]methylene)-2,4-dihydro-3H-pyrazol-3-one 4-[(2-Chloroanilino)methylene]-2-phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one 4-[(Morpholinoamino)methylene]-2-phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one 4-[(Dimethylamino)methylene]-2-phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one 4-(Anilinomethylene)-2-phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one
2-Phenyl-5-(trifluoromethyl)-4-([4-(trifluoromethyl)anilino]methylene)-2,4-dihydro-3H-pyrazol-3-one 4-[(Dimethylamino)methylene]-2-methyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one 4-[(2-Hydroxyanilino)methylene]-2-methyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one

1of4

METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE 1-METHYL-3-(TRIFLUOROMETHYL)-4,5-DIHYDRO-1H-PYRAZOL-5-ONE 1-Methyl-3-trifluormethyl-2-pyrazolin-5-one BUTTPARK 24\09-48 1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one 97% 1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one97% 3-trifluoromethyl-1-methyl-1H-5-Pyrazolone 2-Methyl-5-trifluoromethyl-2,4-dihydro-pyrazol-3-one 1-Methyl-3-(trifluoroMethyl)-1H-pyrazol-5(4H)-one 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one97% 2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one 97% 4,5-Dihydro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-one, 1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one 3H-Pyrazol-3-one, 2,4-dihydro-2-methyl-5-(trifluoromethyl)- 2,4-Dihydro-2-Methyl-5-(Trifluoromethyl)-3H-Pyrazol-3-One 2-METHYL-5-(TRIFLUOROMETHYL)-2,4-DIHYDRO-3H-PYRAZOL-3-ONE 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 1481-02-3 Pyrazole series