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1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE

CAS No.
1481-02-3
Chemical Name:
1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE
Synonyms
BUTTPARK 24\09-48;3-trifluoromethyl-1-methyl-1H-5-Pyrazolone;METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE;1-Methyl-3-trifluormethyl-2-pyrazolin-5-one;1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE;2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one;1-Methyl-3-(trifluoroMethyl)-1H-pyrazol-5(4H)-one;1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one97%;1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one 97%;2-Methyl-5-trifluoromethyl-2,4-dihydro-pyrazol-3-one
CBNumber:
CB3772867
Molecular Formula:
C5H5F3N2O
Molecular Weight:
166.1
MDL Number:
MFCD00051654
MOL File:
1481-02-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:40
Product description Number Pack Size Price
1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one M332183 250mg $55
1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 95% 085366 50g $623
1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE 95.00% HCH0016510 10G $1115.17
1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 95% 085366 1g $37
1-Methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one Y7579 1g $77

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Properties

Melting point 178 °C
Boiling point 101.6±50.0 °C(Predicted)
Density 1.50±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 0.58±0.50(Predicted)
Appearance White to off-white Solid
BRN 5811070
CAS DataBase Reference 1481-02-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P312-P305+P351+P338-P362-P403+P233-P501
Hazard Codes  Xi,T
Risk Statements  25
Safety Statements  45
Hazard Note  Irritant
HS Code  2933119000
NFPA 704
1
2 0

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M332183 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 1481-02-3 250mg $55 2021-12-16 Buy
Matrix Scientific 085366 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 95% 1481-02-3 50g $623 2021-12-16 Buy
American Custom Chemicals Corporation HCH0016510 1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE 95.00% 1481-02-3 10G $1115.17 2021-12-16 Buy
Matrix Scientific 085366 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one 95% 1481-02-3 1g $37 2021-12-16 Buy
AK Scientific Y7579 1-Methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one 1481-02-3 1g $77 2021-12-16 Buy
Product number Packaging Price Buy
M332183 250mg $55 Buy
085366 50g $623 Buy
HCH0016510 10G $1115.17 Buy
085366 1g $37 Buy
Y7579 1g $77 Buy

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Chemical Properties,Uses,Production

Synthesis

Ethyl 4,4,4-trifluoroacetoacetate

372-31-6

Methylhydrazine

60-34-4

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE

1481-02-3

0.1 mL of methylhydrazine and 10 mL of anhydrous ethanol were added to a 250 mL three-necked flask, stirred and heated to 50°C. Subsequently, 0.1 mol of ethyl trifluoroacetoacetate was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the mixture was cooled to promote crystallization. The resulting yellow solid was collected by vacuum filtration and dried. The yield of the final product was 85.8%.

References

[1] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0091; 0092; 0093
[2] Australian Journal of Chemistry, 2010, vol. 63, # 5, p. 785 - 791

372-31-6
60-34-4
1481-02-3
Synthesis of 1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE from Ethyl 4,4,4-trifluoroacetoacetate and Methylhydrazine

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Preparation Products And Raw materials

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Suppliers

Global( 52)Suppliers
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Dayang Chem (Hangzhou) Co.,Ltd.
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Amadis Chemical Company Limited
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Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259138 18621169109 market03@meryer.com China 40228 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30123 84
Energy Chemical 021-021-58432009 400-005-6266 sales8178@energy-chemical.com China 44734 61

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Spectrum

METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE 1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE 1-METHYL-3-(TRIFLUOROMETHYL)-4,5-DIHYDRO-1H-PYRAZOL-5-ONE 2-METHYL-5-(TRIFLUOROMETHYL)-2,4-DIHYDRO-3H-PYRAZOL-3-ONE 1-Methyl-3-trifluormethyl-2-pyrazolin-5-one BUTTPARK 24\09-48 1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one 97% 1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one97% 3-trifluoromethyl-1-methyl-1H-5-Pyrazolone 2-Methyl-5-trifluoromethyl-2,4-dihydro-pyrazol-3-one 1-Methyl-3-(trifluoroMethyl)-1H-pyrazol-5(4H)-one 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one97% 2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one 97% 4,5-Dihydro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-one, 1-Methyl-3-(trifluoromethyl)-2-pyrazolin-5-one 3H-Pyrazol-3-one, 2,4-dihydro-2-methyl-5-(trifluoromethyl)- 2,4-Dihydro-2-Methyl-5-(Trifluoromethyl)-3H-Pyrazol-3-One 1481-02-3 Pyrazole series