ChemicalBook >> CAS DataBase List >>4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]-

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]-

CAS No.
2095668-10-1
Chemical Name:
4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]-
Synonyms
VIT-2763;Vamifeport;Vamifeport, 10 mM in DMSO;4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]-;2-(2-((2-(1H-Benzo[d]imidazol-2-yl)ethyl)amino)ethyl)-N-((3-fluoropyridin-2-yl)methyl)oxazole-4-carboxamide;2-[2-[[2-(1H-Benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]-4-oxazolecarboxamide (ACI)
CBNumber:
CB38134401
Molecular Formula:
C21H21FN6O2
Molecular Weight:
408.43
MDL Number:
MOL File:
2095668-10-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-30 11:39:11

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- Properties

Boiling point 727.8±60.0 °C(Predicted)
Density 1.339±0.06 g/cm3(Predicted)
pka 11.87±0.46(Predicted)
form Solid
color Off-white to light yellow
FDA UNII FUF66UD0KR

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth VID66810 VIT-2763 2095668-10-1 10mg $776.2 2026-06-05 Buy
Biosynth VID66810 VIT-2763 2095668-10-1 25mg $1455.5 2026-06-05 Buy
Biosynth VID66810 VIT-2763 2095668-10-1 50mg $2025 2026-06-05 Buy
ChemScene CS-0044182 VIT-2763 99.93% 2095668-10-1 5mg $213 2026-06-04 Buy
ChemScene CS-0044182 VIT-2763 99.93% 2095668-10-1 10mg $320 2026-06-04 Buy
Product number Packaging Price Buy
VID66810 10mg $776.2 Buy
VID66810 25mg $1455.5 Buy
VID66810 50mg $2025 Buy
CS-0044182 5mg $213 Buy
CS-0044182 10mg $320 Buy

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- Chemical Properties, Uses, Production

Uses

VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia[1].

in vivo

VIT-2763 (30, 100 mg/kg, orally twice daily for 36 days) decreases serum iron and prevented liver iron loading in Hbbth3/+ mice[1].
VIT-2763 did not change the total liver iron[1].
VIT-2763 (30, 100 mg/kg, orally twice daily for 36 days) significantly corrects anemia and improved RBC parameters in Hbbth3/+ mice. VIT-2763 decreases the percentage of ROS-positive RBCs in Hbbth3/+ mice from 67% to 30%[1].
VIT-2763 decreases apoptosis and extends the life span of RBCs in Hbbth3/+ mice[1].

Animal Model:Hbbth3/+ mice[1].
Dosage:30, 100 mg/kg.
Administration:Orally twice daily for 36 days.
Result:Significantly decreased serum iron levels by 77% (30 mg/kg) and 84% (100 mg/kg),
Significantly increased Hb levels (as of day 8 of treatment), RBC counts, mean corpuscular Hb concentration (MCHC), and significantly lowered reticulocyte counts, mean corpuscular Hb (MCH), mean corpuscular volume (MCV), and RBC distribution width (RDW) in Hbbth3/+ mice, as compared with the Hbbth3/+ vehicle group.

References

[1] Vania Manolova, et al. Oral Ferroportin Inhibitor Ameliorates Ineffective Erythropoiesis in a Model of β-Thalassemia. J Clin Invest. 2019 Dec 9;130(1):491-506. DOI:10.1172/JCI129382

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- Suppliers

Global Suppliers ( 28)
Supplier Tel Email Country ProdList Advantage
ChemCell Biomedicine Co.,Ltd. 020-13556033878 2965585218 13556033878 chemcell@hotmail.com China 369 52
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences +1-631-485-4226 inquiry@bocsci.com United States 19935 58
Shandong Jirun Biomedical Technology Co., Ltd. 0539-0539-8613587 17661611089 2639273505@qq.com China 237 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 959 58
Shanghai Xiushi Biomedical Co., LTD 15002184385 15021598081 15002184385 product001@xiushipharm.com China 4710 58

View Latest Price from 4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Vamifeport pictures 2026-08-30 Vamifeport
2095668-10-1
$64.00-231.00 99.91% 10g TargetMol Chemicals Inc.
  • Vamifeport pictures
  • Vamifeport
    2095668-10-1
  • $64.00-231.00
  • 99.91%
  • TargetMol Chemicals Inc.

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- Spectrum

4-Oxazolecarboxamide, 2-[2-[[2-(1H-benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]- Vamifeport, 10 mM in DMSO 2-(2-((2-(1H-Benzo[d]imidazol-2-yl)ethyl)amino)ethyl)-N-((3-fluoropyridin-2-yl)methyl)oxazole-4-carboxamide VIT-2763 Vamifeport 2-[2-[[2-(1H-Benzimidazol-2-yl)ethyl]amino]ethyl]-N-[(3-fluoro-2-pyridinyl)methyl]-4-oxazolecarboxamide (ACI) 2095668-10-1 C21H21FN6O2