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4-Bromobenzo[b]thiophene

4-Bromobenzo[b]thiophene structure

CAS No.: 5118-13-8

Chemical Name:: 4-Bromobenzo[b]thiophene

Synonyms: 4-Bromobenzothiophene;4-BROMO-1-BENZOTHIOPHENE;4-bromo-thiophene;4-Bromothianaphthene;5-cyanobenzothiophene;Bromobenzo[b]thiophene;8-Quinolinol phosphate;4-BROMO-BENZO[B]THIOPHENE;Brexpiprazole intermdiate;Benzo[b]thiophene,4-broMo-

CBNumber:: CB3813658

Molecular Formula:: C8H5BrS

Molecular Weight:: 213.09

MDL Number:: MFCD08669544

MOL File:: 5118-13-8.mol

MSDS File:: SDS

Last updated:2026-05-28 02:16:38

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4-Bromobenzo[b]thiophene Properties

Boiling point	144 °C(Press: 20 Torr)
Density	1.649±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
form	solid
color	White to off-white
InChI	InChI=1S/C8H5BrS/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H
InChIKey	QPBSEYFVZDMBFW-UHFFFAOYSA-N
SMILES	C12=CC=CC(Br)=C1C=CS2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P271-P280
Hazard Codes	Xi
Hazard Note	Irritant
HS Code	2934999090
REACH Registrations	Active

4-Bromobenzo[b]thiophene price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	266897	3-Bromobenzo(b)thiophene Asreported	5118-13-8	1g	$588	2026-06-03	Buy
Usbiological	266897	3-Bromobenzo(b)thiophene Asreported	5118-13-8	2g	$885	2026-06-03	Buy
Usbiological	266897	3-Bromobenzo(b)thiophene Asreported	5118-13-8	5g	$1663	2026-06-03	Buy
Usbiological	266897	3-Bromobenzo(b)thiophene Asreported	5118-13-8	10g	$2584	2026-06-03	Buy
Usbiological	266897	3-Bromobenzo(b)thiophene Asreported	5118-13-8	25g	$4778	2026-06-03	Buy

Product number	Packaging	Price	Buy
266897	1g	$588	Buy
266897	2g	$885	Buy
266897	5g	$1663	Buy
266897	10g	$2584	Buy
266897	25g	$4778	Buy

4-Bromobenzo[b]thiophene Chemical Properties, Uses, Production

Synthesis

The traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene.

Uses

4-Bromobenzo[b]thiophene is an important intermediate in the drug ipiprazole for the treatment of schizophrenia.

References

[1] Patent: US2017/158680, 2017, A1. Location in patent: Paragraph 0361; 0368; 0369
[2] Tetrahedron Letters, 2004, vol. 45, # 52, p. 9645 - 9647
[3] Organic Process Research and Development, 2012, vol. 16, # 8, p. 1449 - 1454
[4] Patent: WO2007/92751, 2007, A2. Location in patent: Page/Page column 20-21
[5] Patent: EP1724277, 2006, A1. Location in patent: Page/Page column 28-29

4-Bromobenzo[b]thiophene synthesis

Synthesis of 4-Bromobenzo[b]thiophene from Thianaphthene

4-Bromobenzo[b]thiophene Preparation Products And Raw materials

Raw materials

4-Bromo-benzo[b]thiophene-2-carboxylic acid Dimethyl sulfoxide Acetic acid Silver carbonate

Preparation Products

6-Bromo-benzo[b]thiophene (1-Benzothiophen-4-yl)boronic acid

4-Bromobenzo[b]thiophene Suppliers

Global Suppliers ( 315)

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangsu Haici Biopharmaceutical Co., Ltd.	15722465851 15722465851	2545001360@qq.com	China	183	58
Chengdu Aofan Pharmtech Co.,Ltd	15281070185; 13038283958	2865097598@qq.com	China	111	55
Nanjing CoreTech Biomedical Co,.Ltd	025-52880806 13770327895	API@core-tech.com.cn	China	52	58
Bayee Biotech (Anqing) Co., Ltd.	0556-5032306 18917961636	wtx@bayeebio.com	China	145	61
Jinan Lide Pharmaceutical Technology Co., Ltd.	0531-68654990 18560195202	leadgxm@leadchem.net	China	186	58
Sichuan Fanzhijian Biomedical Technology Co., Ltd	15281070185	2865097598@qq.com	China	60	58
Anqing CHICO Pharmaceutical Co., Ltd.	18061456370	sales@chicopharm.com	China	500	65
Taizhou Yuxin Biotechnology Co., Ltd.,	+86-0576--88902229 +86-13968687450	yuxin@yuxchem.com	China	191	58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.	022-60189726 18812034280	188120342808@163.com	China	143	61
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
Jiangsu Haici Biopharmaceutical Co., Ltd.	58
Chengdu Aofan Pharmtech Co.,Ltd	55
Nanjing CoreTech Biomedical Co,.Ltd	58
Bayee Biotech (Anqing) Co., Ltd.	61
Jinan Lide Pharmaceutical Technology Co., Ltd.	58
Sichuan Fanzhijian Biomedical Technology Co., Ltd	58
Anqing CHICO Pharmaceutical Co., Ltd.	65
Taizhou Yuxin Biotechnology Co., Ltd.,	58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.	61
J & K SCIENTIFIC LTD.	76

View Latest Price from 4-Bromobenzo[b]thiophene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-16	4-Bromobenzo[b]thiophene 5118-13-8		1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-08-20	4-BROMO-BENZO[B]THIOPHENE 5118-13-8	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2025-11-19	4-Bromobenzo[b]thiophene 5118-13-8		1kg	99%	1000kg	Shanghai Joiny Pharmaceutical Co.,LTD

4-Bromobenzo[b]thiophene
5118-13-8
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-BROMO-BENZO[B]THIOPHENE
5118-13-8
$1.10
99.00%
Dideu Industries Group Limited

4-Bromobenzo[b]thiophene
5118-13-8
$0.00
99%
Shanghai Joiny Pharmaceutical Co.,LTD

4-Bromobenzo[b]thiophene Spectrum

4-BROMO-BENZO[B]THIOPHENE(5118-13-8)¹HNMR

5118-13-8 (4-Bromobenzo[b]thiophene) Related Search:

Thianaphthene Brexpiprazole-d8 4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butan-1-ol 4-Bromo-benzo[b]thiophene-2-carboxylic acid Brexpiprazole Impurity 5 HCl

Brexpiprazole Impurity 36 Brexpiprazole Impurity 20 Brexpiprazole Impurity 2 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one Brexpiprazole Impurity 7

Brexpiprazole Impurity 18 Brexpiprazole Impurity 24 Brexpiprazole Impurity 22 Brexpiprazole Impurity 21 8-(benzo[b]thiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride

7,7'-(butane-1,4-diylbis(oxy))bis(quinolin-2(1H)-one) (E)-N-(3-Methoxy-phenyl)-3-phenyl-acrylamide 5-Hydroxy-2(1H)-quinolinone

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4-BROMO-BENZO[B]THIOPHENE 4-Bromobenzothiophene 4-BROMO-1-BENZOTHIOPHENE 4-Bromothianaphthene 5-cyanobenzothiophene 4-bromo-thiophene Benzo[b]thiophene,4-broMo- 4-Bromo-1-benzothiophene, 4-Bromothianaphthene 4-BROMO-BENZO[B]THIOPHENE ISO 9001：2015 REACH Brexpiprazole intermdiate CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE Bromobenzo[b]thiophene Brexpiprazole Impurity 13 4-Bromo benzo[b]thiophene 8-Quinolinol phosphate 5118-13-8 Benzothiophene Halogenated Organohalides