ChemicalBook >> CAS DataBase List >>1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
- CAS No.
- 864754-16-5
- Chemical Name:
- 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
- Synonyms
- ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate;ethyl 2-(4-(4,4,5,5-tet;1-(Ethoxycarbonylmethyl)-1H<;1-(Ethoxycarbonylmethyl)pyrazole-4-boronic Acid Pin;1-(Ethoxycarbonylmethyl)pyrazole-4-boronic Acid Pinacol Ester;ethyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-py...;1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER;1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester 97%;1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester;ethyl 2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate
- CBNumber:
- CB3836680
- Molecular Formula:
- C13H21BN2O4
- Molecular Weight:
- 280.13
- MDL Number:
- MFCD08706026
- MOL File:
- 864754-16-5.mol
- MSDS File:
- SDS
Last updated:2026-05-28 03:38:29
| Product description | Number | Pack Size | Price |
| 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester 97% | 683566 | 1g | $143 |
| 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester 97% | 683566 | 250mg | $63.8 |
| 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97% | OR302124 | 250mg | $21 |
| 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97% | OR302124 | 1g | $25 |
| 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97% | OR302124 | 5g | $86 |
| More product size | |||
| Boiling point | 390.8±22.0 °C(Predicted) |
|---|---|
| Density | 1.12±0.1 g/cm3(Predicted) |
| refractive index | n20/D 1.4814 |
| Flash point | 110 °C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | liquid |
| pka | 1.49±0.10(Predicted) |
| Appearance | Light yellow to yellow Liquid |
| InChI | 1S/C13H21BN2O4/c1-6-18-11(17)9-16-8-10(7-15-16)14-19-12(2,3)13(4,5)20-14/h7-8H,6,9H2,1-5H3 |
| InChIKey | YUEZJHOSHBTWPV-UHFFFAOYSA-N |
| SMILES | CCOC(=O)Cn1cc(cn1)B2OC(C)(C)C(C)(C)O2 |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 2933199090 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 683566 | 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester 97% | 864754-16-5 | 1g | $143 | 2026-04-30 | Buy |
| Sigma-Aldrich | 683566 | 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester 97% | 864754-16-5 | 250mg | $63.8 | 2023-01-07 | Buy |
| Apolloscientific | OR302124 | 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97% | 864754-16-5 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR302124 | 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97% | 864754-16-5 | 1g | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR302124 | 1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97% | 864754-16-5 | 5g | $86 | 2026-06-04 | Buy |
1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER Chemical Properties,Uses,Production
Chemical Properties
liquid
Uses
1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester
Synthesis
82231-58-1
73183-34-3
864754-16-5
The general procedure for the synthesis of 1-(ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester from ethyl 4-bromo-1H-pyrazole-1-acetate and bis-boronic acid pinacol ester was carried out as follows: firstly, 4,4,5,5-tetramethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaboro Heterocyclopentane (436 mg, 1.72 mmol) was dissolved in DMF (10 mL). Subsequently, KOAc (420 mg, 4.29 mmol) and Pd(dppf)Cl2-CH2Cl2 (35 mg, 0.043 mmol) were added sequentially. The reaction mixture was heated to 80 °C and a solution of ethyl 4-bromo-1H-pyrazole-1-acetate (333 mg, 1.43 mmol) in DMF (10 mL) was added dropwise at this temperature. The reaction mixture was stirred at 80 °C overnight and then evaporated to dryness. Finally, the residue was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether = 1:10) to afford the target product 1-(ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester (76 mg, 19% yield).
References
[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 52
[2] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 21, p. 6804 - 6820
1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 102)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
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| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9048 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER manufacturers
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![ethyl 2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate pictures](/ProductImageEN1/2025-07/Small/d0cee09d-4b2e-4186-a7b6-e40e70c4870b.png) |
2026-07-02 | ethyl 2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate
864754-16-5
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2021-07-13 | 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
864754-16-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
864754-16-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- ethyl 2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate
864754-16-5
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
864754-16-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
864754-16-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
864754-16-5(1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER)Related Search:
1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER
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ethyl 2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate
Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetate
1-(Ethoxycarbonylmethyl)pyrazole-4-boronic Acid Pinacol Ester
1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester 97%
Ethyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]acetate
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1-(Ethoxycarbonylmethyl)-1H-pyrazole-4-boronic acid pinacol ester
ethyl 2-(4-(4,4,5,5-tet
1-(Ethoxycarbonylmethyl)pyrazole-4-boronic Acid Pin
ethyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate
ethyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-py...
1-(Ethoxycarbonylmethyl)-1H<
ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate
864754-16-5
Boronate Esters
Boronic Acids and Derivatives
Chemical Synthesis
Heteroaryl Boronate Esters
Organometallic Reagents
