Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Structure
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester structure
CAS No.
847818-70-6
Chemical Name:
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
Synonyms
1-Eth;1-Ethyl-1H-pyrazole-4-boronic acid, pina;1-Ethylpyrazole-4-boronic Acid Pinacol Ester;1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester;1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester;1-Ethylpyrazole-4-boronic acid pinacol ester - [E10401];1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-p...
CBNumber:
CB11486453
Molecular Formula:
C11H19BN2O2
Molecular Weight:
222.09
MDL Number:
MFCD09864188
MOL File:
847818-70-6.mol
Last updated:2025-07-24 18:13:54
Product description Number Pack Size Price
1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 706205 250mg $40.7
1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 706205 1g $126
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole E1348 1G $67
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole E1348 5G $231
1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester E926225 250mg $55
More product size
Request For Quotation

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Properties

Melting point 44-49°C
Boiling point 322.6±15.0 °C(Predicted)
Density 1.04±0.1 g/cm3(Predicted)
refractive index 1.48
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 2.11±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
InChI InChI=1S/C11H19BN2O2/c1-6-14-8-9(7-13-14)12-15-10(2,3)11(4,5)16-12/h7-8H,6H2,1-5H3
InChIKey UGCRHVPUHAXAAE-UHFFFAOYSA-N
SMILES N1(CC)C=C(B2OC(C)(C)C(C)(C)O2)C=N1
CAS DataBase Reference 847818-70-6
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  2933199090
NFPA 704
1
2 0

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 706205 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 847818-70-6 250mg $40.7 2025-07-31 Buy
Sigma-Aldrich 706205 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 847818-70-6 1g $126 2025-07-31 Buy
TCI Chemical E1348 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 847818-70-6 1G $67 2025-07-31 Buy
TCI Chemical E1348 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 847818-70-6 5G $231 2025-07-31 Buy
TRC E926225 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 847818-70-6 250mg $55 2021-12-16 Buy
Product number Packaging Price Buy
706205 250mg $40.7 Buy
706205 1g $126 Buy
E1348 1G $67 Buy
E1348 5G $231 Buy
E926225 250mg $55 Buy

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Chemical Properties,Uses,Production

Synthesis

4-Pyrazoleboronic acid pinacol ester

269410-08-4

Iodoethane

75-03-6

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

847818-70-6

To a solution of N,N-dimethylformamide (DMF, 10 mL) of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (1.0 g, 5.2 mmol) was added cesium carbonate (2.5 g, 7.7 mmol) and ethyl iodide (1.2 mL, 15 mmol). The reaction mixture was stirred at room temperature for 12 hours. After the reaction was completed, the reaction mixture was diluted with water (30 mL). The aqueous phase was extracted with dichloromethane (DCM, 30 mL x 3). The organic layers were combined and dried over anhydrous sodium sulfate (Na2SO4) and subsequently concentrated under reduced pressure. The residue was purified by silica gel column chromatography using petroleum ether (PE)/ethyl acetate (EtOAc) (2:1, v/v) as eluent to afford the colorless oily product 1-ethyl-1H-pyrazole-4-boronic acid pinacol ester (880 mg, 77% yield). Mass spectrometric (MS) analysis (electrospray ionization, cation mode) showed m/z: 223.25 [M + 1]+.

References

[1] Patent: WO2016/615, 2016, A1. Location in patent: Paragraph 00655
[2] Patent: EP1798229, 2007, A1. Location in patent: Page/Page column 130
[3] Patent: US2010/240634, 2010, A1. Location in patent: Page/Page column 67-68
[4] Patent: WO2018/102452, 2018, A2. Location in patent: Paragraph 425; 426
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 19, p. 5299 - 5302

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Preparation Products And Raw materials

Raw materials

Bis(pinacolato)diboron 4-Pyrazoleboronic acid pinacol ester 1-Azetidinecarboxylic acid, 3-[4-[6-[(6-methyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)thio]-3-quinolinyl]-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester Iodoethane 4-Bromo-1-ethyl-1H-pyrazole
Cesium carbonate N,N-Dimethylformamide

1of2

Preparation Products

4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Suppliers

Global( 145)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10035 58
Antai Fine Chemical Technology Co.,Limited 		18503026267 info@antaichem.com CHINA 9636 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Chengdu Aslee Biopharmaceuticals, Inc. 		28-85305008 CHINA 964 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
Fuxin Pharmaceutical 		58
Antai Fine Chemical Technology Co.,Limited 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Chengdu Aslee Biopharmaceuticals, Inc. 		58

View Lastest Price from 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester pictures 2021-07-13 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
847818-70-6
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester pictures 2021-07-10 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
847818-70-6
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester pictures 2019-07-06 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
847818-70-6
 US $1.00 / KG 1KG 98%-100% 1 Career Henan Chemical Co

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Spectrum

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester(847818-70-6)1HNMR

847818-70-6(1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester)Related Search:

1-Propyl-1H-pyrazole-4-boronic acid pinacol ester 1-ISOBUTYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 1-Benzyl-1H-pyrazole-4-boronic acid pinacol ester 4-Pyrazoleboronic acid pinacol ester
1H-PYRAZOLE-4-BORONIC ACID 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1-THIOPHEN-2-YLMETHYL-1H-PYRAZOLE 2-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE 3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE
1-(3-METHYLBUTYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER 4-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE 1-ACETYL-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER 1-(ETHOXYCARBONYLMETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER 1-(2,2-DIMETHOXY-ETHYL)-3,5-DIMETHYL-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-PYRAZOLE
1-(2-MORPHOLINOETHYL)-1H-PYRAZOLE-4-BORONIC ACID, PINACOL ESTER 1-(2,2-DIMETHOXY-ETHYL)-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-PYRAZOLE 1-[1,3]DIOXOLAN-2-YLMETHYL-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-PYRAZOLE

1of4

1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (1-ethyl-1H-pyrazol-4-yl)boronate 1-Ethylpyrazole-4-boronic Acid Pinacol Ester 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1H-Pyrazole, 1-ethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 1-Eth 2-(1-Ethyl-1H-pyrazol-4yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1-Ethyl-1H-pyrazole-4-boronic acid, pina 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-p... 1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 1-Ethylpyrazole-4-boronic acid pinacol ester - [E10401] 847818-70-6 C11H21BN2O3