ChemicalBook >> CAS DataBase List >>4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)-

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)-

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- structure

CAS No.: 2270984-21-7

Chemical Name:: 4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)-

Synonyms: Gcase activator 3;(S)-N-[(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl]-N-methyl-2-(3-pyridyl)quinazolin-4-amine;4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)-

CBNumber:: CB38848137

Molecular Formula:: C23H20N4O2

Molecular Weight:: 384.43

MDL Number:

MOL File:: 2270984-21-7.mol

MSDS File:: SDS

Last updated:2025-10-29 15:43:00

Request For Quotation

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- Properties

Boiling point	492.8±45.0 °C(Predicted)
Density	1.277±0.06 g/cm3(Predicted)
pka	4.74±0.30(Predicted)

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	45307	GCase Activator 3 ≥98%	2270984-21-7	1mg	$319	2026-04-30	Buy
Cayman Chemical	45307	GCase Activator 3 ≥98%	2270984-21-7	5mg	$718	2026-04-30	Buy
Cayman Chemical	45307	GCase Activator 3 ≥98%	2270984-21-7	10mg	$957	2026-04-30	Buy
ChemScene	CS-0978826	Gcase activator 3 99.67%	2270984-21-7	1mg	$357	2026-06-04	Buy
ChemScene	CS-0978826	Gcase activator 3 99.67%	2270984-21-7	5mg	$791	2026-06-04	Buy

Product number	Packaging	Price	Buy
45307	1mg	$319	Buy
45307	5mg	$718	Buy
45307	10mg	$957	Buy
CS-0978826	1mg	$357	Buy
CS-0978826	5mg	$791	Buy

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- Chemical Properties, Uses, Production

Uses

Gcase activator 3 (compound 9Q) is a glucosidase (Glucosidase, GCase) activator that can partially stabilize GCase and increase its activity. Gcase activator 3 reduces mutant GCase protein misfolding and degradation in fibroblasts and dopaminergic midbrain neurons. Gcase activator 3 can be used in the study of Parkinson's disease (PD) and related synucleinopathies[1].

References

[1] Zheng J, et al. Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase. J Med Chem. 2019 Feb 14;62(3):1218-1230. DOI:10.1021/acs.jmedchem.8b01294

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9729	58
Guangzhou Younan Technology Co., Ltd	020-82000279 18988941452	YN_research@163.com	China	2984	58
Suzhou Chenrui Biotechnology Co. LTD	17625585511	1580084073@qq.com	China	992	58
Shaoyuan Technology (Shanghai) Co., Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	9985	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai Chaolan Chemical Technology Center	58
Guangzhou Younan Technology Co., Ltd	58
Suzhou Chenrui Biotechnology Co. LTD	58
Shaoyuan Technology (Shanghai) Co., Ltd.	58
TargetMol Chemicals Inc.	58

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- Spectrum

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)-(2270984-21-7)¹HNMR

2270984-21-7 (4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)-) Related Search:

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- 2-(3,4-dimethoxyphenyl)-7-ethoxy-6-methoxy-N-(3-morpholin-4-ylpropyl)quinazolin-4-amine 4-Quinazolinamine, N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)- 2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-7-ethoxy-6-methoxy-N-methylquinazolin-4-amine GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE

Ganglioside GM1 (porcine brain) (sodium salt)

1of2

4-Quinazolinamine, N-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]-N-methyl-2-(3-pyridinyl)- Gcase activator 3 (S)-N-[(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl]-N-methyl-2-(3-pyridyl)quinazolin-4-amine 2270984-21-7