Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Structure
1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose structure
CAS No.
21740-23-8
Chemical Name:
1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose
Synonyms
Chloro sugar;NSC 140594;5G/25G/1KG;Chloride sugar;Oxygen-2-deoxy-D-ribose;Trifluridine intermediate;chlorobenzoyl)-2-deoxy-D-ribose;3,5-O-bis(p-chlorobenzoyl)-2-deoxy-α-D-;1-Cl-3,5-bis-(4-cl-bz)- 2-deoxy-D-ribofuranose;1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose
CBNumber:
CB3952869
Molecular Formula:
C19H15Cl3O5
Molecular Weight:
429.67
MDL Number:
MFCD23843803
MOL File:
21740-23-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-19 07:28:27
Request For Quotation

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Properties

Melting point 110-118°C (dec.)
Boiling point 530.6±50.0 °C(Predicted)
Density 1.46±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Solid
color White to Off-White
Stability Not stable in Solution
InChI InChI=1/C19H15Cl3O5/c20-13-5-1-11(2-6-13)18(23)25-10-16-15(9-17(22)26-16)27-19(24)12-3-7-14(21)8-4-12/h1-8,15-17H,9-10H2/t15-,16+,17-/s3
InChIKey QEHCZULNFYDPPL-KIQRZSAINA-N
SMILES C([C@H]1O[C@H](Cl)C[C@@H]1OC(C1C=CC(Cl)=CC=1)=O)OC(C1C=CC(Cl)=CC=1)=O |&1:1,3,6,r|

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
REACH Registrations Active

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-D432235-2.5G 3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride 21740-23-8 2.5g $135 2026-06-03 Buy
TRC TRC-D432235-1G 3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride 21740-23-8 1g $72 2026-06-03 Buy
Usbiological 009147 3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride 21740-23-8 250mg $418 2026-06-03 Buy
Biosynth MC145897 1-Chloro-3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranose 21740-23-8 50g $150 2026-06-04 Buy
Biosynth MC145897 1-Chloro-3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranose 21740-23-8 25g $150 2026-06-04 Buy
Product number Packaging Price Buy
TRC-D432235-2.5G 2.5g $135 Buy
TRC-D432235-1G 1g $72 Buy
009147 250mg $418 Buy
MC145897 50g $150 Buy
MC145897 25g $150 Buy

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Chemical Properties, Uses, Production

Chemical Properties

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose is White Solid

Uses

Intermediate used in the synthesis of nucleotide analogs.Unstable in solution!

Uses

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose is used in the synthesis of nucleotide analogs. Unstable in solution!

Synthesis

α-D-erythro-Pentofuranoside, methyl 2-deoxy-, 3,5-dibenzoate

80339-59-9

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose

21740-23-8

Example 3: Preparation of 1-[3,5-di-O-(p-chlorobenzoyl)]-2-deoxy-α-D-ribofuranosyl chloride To a 250 mL four-necked round-bottomed flask under nitrogen protection was added 1-O-methyl-3,5-di-O-(p-chlorobenzoyl)-2-deoxy-α/β-D-ribofuranose (15.94 g), glacial acetic acid (60 mL), anhydrous chloroform (30 mL), anhydrous dioxane (30 mL) and acetyl chloride (0.87 g). Under stirring conditions, gaseous HCl (11.5 g) was slowly passed while the reaction temperature was controlled between 13 and 15 °C. During this process, 1-[3,5-di-O-(p-chlorobenzoyl)]-2-deoxy-α-D-ribofuranosyl chloride was gradually crystallized and precipitated.After the completion of HCl passage, the reaction mixture was continued to be stirred at 12 °C for 20 min. Subsequently, the product was collected by filtration and washed with anhydrous hexane (20 mL). After drying, 12.4 g of the target compound 1-[3,5-di-O-(p-chlorobenzoyl)]-2-deoxy-α-D-ribofuranosyl chloride was obtained as a white powder in 77% yield.

References

[1] Patent: US2010/249394, 2010, A1. Location in patent: Page/Page column 4-5

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose synthesis

80339-59-9
21740-23-8
Synthesis of 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose from α-D-erythro-Pentofuranoside, methyl 2-deoxy-, 3,5-dibenzoate

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Preparation Products And Raw materials

Raw materials

α-D-erythro-Pentofuranoside, methyl 2-deoxy-, 3,5-dibenzoate Chloroform Acetic acid 1,4-Dioxane Hydrochloric acid
Acetyl chloride

1of2

Preparation Products

3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Suppliers

Global Suppliers ( 235)
Supplier Tel Email Country ProdList Advantage
Wuhu Nuowei Chemical Technology Co., Ltd 0553-8233716 18055326116 sales@nuowei-chem.com China 742 55
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14072 58
Lianyungang Shenghe Biotechnology Co., Ltd. 0518-87108777 13585296001 haizaofu@163.com China 44 58
Innobio Pharm Co.,Ltd 15600141006 sales@innovbiopharm.com China 117 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Wuhu Huaren Science and Technology Co., Ltd. 5842013 18155347026 xujuan@hdpharm.com China 255 64
Supplier Advantage
Wuhu Nuowei Chemical Technology Co., Ltd 55
Shanghai YuLue Chemical Co., Ltd. 55
Wuxi Helen Biotechnology Co., Ltd., 58
Lianyungang Shenghe Biotechnology Co., Ltd. 58
Innobio Pharm Co.,Ltd 58
J & K SCIENTIFIC LTD. 76
INTATRADE GmbH 66
Beijing Ouhe Technology Co., Ltd 60
Jia Xing Isenchem Co.,Ltd 66
Wuhu Huaren Science and Technology Co., Ltd. 64

View Latest Price from 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose pictures 2026-09-18 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose
21740-23-8
 1KG 98.0% 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
1-Chloro-3,5-Bis-(4-Chlorobenzoyl)-2-Deoxy-D-Ribofuranose pictures 2026-06-30 1-Chloro-3,5-Bis-(4-Chlorobenzoyl)-2-Deoxy-D-Ribofuranose
21740-23-8
 1KG 95% 20Tons Shaanxi Dideu New Materials Co. Ltd
1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose pictures 2025-04-04 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose
21740-23-8
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Spectrum

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose(21740-23-8)1HNMR

21740-23-8 (1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose) Related Search:

1-Acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose 2,3-O-Isopropylidene-D-ribofuranoside 1-O-Methyl-2-deoxy-D-ribose beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate (5-acetyloxy-3,4-dibenzoyloxy-oxolan-2-yl)methyl benzoate
2-Deoxy-D-ribose 1-CHLORO-3,5-DI-(P-CHLOROBENZOYL)-2-DEOXY-D-RIBOSE,88+% 2-Methoxyethoxymethyl chloride 3-Chloropropyl acetate 5-Chloropentyl benzoate
5-Chloropentyl acetate DNA, single stranded, imm. on cellulose, from calf thymus* 1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-D-ribose Difluorochloromethane Chloro 2,3,5-tri-O-p-chlorobenzoyl-beta-D-ribofuranoside
2,3,5-Tri-O-benzyl-L-arabinofuranose 1-(Benzyloxy)-3-chloropropane 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose

1of4

chlorobenzoyl)-2-deoxy-D-ribose 3,5-di-O-(p-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl chloride 3,5-bis[o-(p-chlorbenzoyl)]-alpha-D-ribofuranosyl chloride [(2S,3R,5R)-5-chloro-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate 3,5-O-Bis(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride 1-Chloro-3,5-di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranose 1-a-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose 2-Deoxy-3,5-di-O-(4-chlorobenzoyl)-alpha-D-ribofuranosyl Chloride Chloride sugar Trifluridine intermediate 1-Cl-3,5-bis-(4-cl-bz)- 2-deoxy-D-ribofuranose 1-Chloro-3,5-bis-(4-chlorobenzoyl)-2-deoxy-D-ribofuranose [5-Chloro-2-[(4-chlorobenzoyl)oxymethyl]oxolan-3-yl] 4-chlorobenzoate 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose (4S,5R)-2-chloro-4-benzoyloxy-5-(benzoyloxymethyl)tetrahydrofuran 1-α-Chloro-3,5-di-O-(4-chlorobenzoyl) -2-deoxy-D-ribofuranose (2R,3S,4R,5R)-5-Chloro-2-((4-chlorobenzoyloxy)methyl)-4-hydroxytetrahydrofuran-3-yl 4-chlorobenzoate 3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride 1-Chloro-2-deoxy-3,5-O-bis(p-chlorobenzoyl)-α-D-erythro-pentofuranose 3,5-Bis(4-chlorobenzoyl)-2-deoxy-.alpha.-D-ribofuranosyl Chloride NSC 140594 5G/25G/1KG 3,5-O-Bis(p-chlorobenzoyl)-2-deoxy-alpha-D-ribofuranosyl chloride a-D-erythro-Pentofuranosylchloride, 2-deoxy-, 3,5-bis(4-chlorobenzoate) [(2R,3S,4R,5R)-5-chloro-3-[(4-chlorophenyl)carbonyloxy]-4-hydroxyoxolan-2-yl]Methyl 4-chlorobenzoate (2S,3R,5R)-5-Chloro-2-(((4-chlorobenzoyl)oxy)-methyl)tetrahydrofuran-3-yl 4-chlorobenzoate 1-Chloro-2-deoxy-3,5-O-bis(4-chlorobenzoyl)-alpha-D-erythro-pentofuranose (2R,3S,5R)-5-Chloro-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate α-?D-?erythro-?Pentofuranosyl chloride, 2-?deoxy-?, 3,?5-?bis(4-?chlorobenzoate) "3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl Chloride" Chloro sugar 3,5-O-bis(p-chlorobenzoyl)-2-deoxy-α-D- 2-deoxy-α-D-erythro-Pentofuranosyl chloride 3,5-bis(4-chlorobenzoate) 1-(3,5-di-O-(4-chlorobenzoyl) -2-deoxy-alpha-D-ribofuranosyl) chloride 1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-ribofuranose [5-chloro-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate Oxygen-2-deoxy-D-ribose 3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride 2-Deoxy-alpha-D-erythro-pentofuranosyl chloride 3,5-bis(4-chlorobenzoate) 1-Chloro-3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranose 21740-23-8 Bases & Related Reagents Intermediates Nucleotides