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KRIBB 3

KRIBB 3 structure

CAS No.: 129414-88-6

Chemical Name:: KRIBB 3

Synonyms: 4-Ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]phenol;Phenol, 4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-;KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole);4-ethyl-3-methoxy-6-[4-(4-methoxyphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone;KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole), Hsp27 inhibitor

CBNumber:: CB3972401

Molecular Formula:: C19H19NO4

Molecular Weight:: 325.36

MDL Number:: MFCD00710140

MOL File:: 129414-88-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:56:38

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KRIBB 3 Properties

Melting point	147-148 °C
Boiling point	467.5±45.0 °C(Predicted)
Density	1.181±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO: 25 mM
form	A solid
pka	8.51±0.48(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301-H413

Precautionary statements

P264-P270-P301+P310-P321-P330-P405-P501

Hazard Codes

Risk Statements

RIDADR

UN 2811 6.1/PG 3

NFPA 704

	0
2		0

KRIBB 3 price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	23973	KRIBB3 ≥98%	129414-88-6	5mg	$332	2024-03-01	Buy
TRC	K660308	KRIBB3	129414-88-6	5mg	$280	2021-12-16	Buy
AK Scientific	1083CE	Kribb3	129414-88-6	5mg	$467	2021-12-16	Buy
American Custom Chemicals Corporation	API0003091	5-(5-ETHYL-2-HYDROXY-4-METHOXYPHENYL)-4-(4-METHOXYPHENYL)ISOXAZOLE 95.00%	129414-88-6	5MG	$849.97	2021-12-16	Buy
DC Chemicals	DC11375	KRIBB3 >98%	129414-88-6	100mg	$650	2021-12-16	Buy

Product number	Packaging	Price	Buy
23973	5mg	$332	Buy
K660308	5mg	$280	Buy
1083CE	5mg	$467	Buy
API0003091	5MG	$849.97	Buy
DC11375	100mg	$650	Buy

KRIBB 3 Chemical Properties,Uses,Production

Uses

Kribb3 is an inhibitor for microtubule. KRIBB3 inhibits the proliferation of cancer cells with GI50 of 0.2-2.5 μM, arrests cell cycle at G2/M phase, and induces apoptosis in HCT-116. Kribb3 exhibits antitumor activity in mouse models[1].

References

[1] Shin KD, et al., KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells. Biochem Pharmacol. 2008 Jan 15;75(2):383-94. DOI:10.1016/j.bcp.2007.08.027

KRIBB 3 Preparation Products And Raw materials

Raw materials

Preparation Products

KRIBB 3 Suppliers

Global( 20)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11963	58
Aladdin Scientific		tp@aladdinsci.com	United States	50089	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49709	58

Supplier	Advantage
BOC Sciences	65
Amadis Chemical Company Limited	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Energy Chemical	58
TargetMol Chemicals Inc.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Aladdin Scientific	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

129414-88-6(KRIBB 3)Related Search:

4-Ethyl-2-(isoxazol-5-yl)phenol 4-Phenylisoxazole KRIBB 3 2-(5-ISOXAZOLYL)-4-METHYLPHENOL 5-(4-METHOXYPHENYL)ISOXAZOLE

2-(5-ISOXAZOLYL)PHENOL

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KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole) 4-ethyl-3-methoxy-6-[4-(4-methoxyphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone Phenol, 4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]- 4-Ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]phenol KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole), Hsp27 inhibitor 129414-88-6