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6-Hydroxy-chroman-4-one

6-Hydroxy-chroman-4-one Structure
6-Hydroxy-chroman-4-one structure
CAS No.
80096-64-6
Chemical Name:
6-Hydroxy-chroman-4-one
Synonyms
6-Hydroxy-4-chromanone;6-HYDROXY-CHROMAN-4-ONE;6-hydroxy-2,3-dihydrochroMen-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-6-hydroxy-
CBNumber:
CB41010905
Molecular Formula:
C9H8O3
Molecular Weight:
164.16
MDL Number:
MOL File:
80096-64-6.mol
Last updated:2026-01-13 11:19:14
Product description Number Pack Size Price
6-Hydroxy-chroman-4-one 2500AC 100mg $136
6-HYDROXY-CHROMAN-4-ONE 95.00% CHM1043792 5MG $504.91
6-hydroxychroman-4-one 98% CM133551 1g $239
6-Hydroxy-chroman-4-one 98% CD11054874 1g $253
6-Hydroxy-chroman-4-one 80096646 1g $255
Request For Quotation

6-Hydroxy-chroman-4-one Properties

Melting point 129-131 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling point 372.4±42.0 °C(Predicted)
Density 1.343±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 9.58±0.20(Predicted)
Appearance Off-white to light yellow Solid
InChI InChI=1S/C9H8O3/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-2,5,10H,3-4H2
InChIKey HTKPIKIGEYFNBY-UHFFFAOYSA-N
SMILES C1OC2=CC=C(O)C=C2C(=O)C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

6-Hydroxy-chroman-4-one price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 2500AC 6-Hydroxy-chroman-4-one 80096-64-6 100mg $136 2021-12-16 Buy
American Custom Chemicals Corporation CHM1043792 6-HYDROXY-CHROMAN-4-ONE 95.00% 80096-64-6 5MG $504.91 2021-12-16 Buy
Chemenu CM133551 6-hydroxychroman-4-one 98% 80096-64-6 1g $239 2021-12-16 Buy
Crysdot CD11054874 6-Hydroxy-chroman-4-one 98% 80096-64-6 1g $253 2021-12-16 Buy
Alichem 80096646 6-Hydroxy-chroman-4-one 80096-64-6 1g $255 2021-12-16 Buy
Product number Packaging Price Buy
2500AC 100mg $136 Buy
CHM1043792 5MG $504.91 Buy
CM133551 1g $239 Buy
CD11054874 1g $253 Buy
80096646 1g $255 Buy

6-Hydroxy-chroman-4-one Chemical Properties,Uses,Production

Uses

6-Hydroxy-chroman-4-one is used in the preparation of novels parasite transmission blocking antimalarials targeting male gametes

Synthesis

6-Methoxy-4-chromanone

5802-17-5

6-Hydroxy-chroman-4-one

80096-64-6

(3) Preparation of 2,3-dihydro-6-hydroxychromen-4-one: 6-methoxychromen-dihydropyran-4-one (2.9 g, 0.0163 mol) was sequentially added to a mixed solution of glacial acetic acid (20 mL) and HBr (>40%, 20 mL), stirred and refluxed for 1 h. The reaction solution was then extracted with ethyl acetate. Upon completion of the reaction, the pH of the reaction solution was adjusted to 10-11 with KOH solution, and then the pH of the aqueous layer was adjusted to 2-3 with concentrated hydrochloric acid.Subsequently, the aqueous layer was extracted with ethyl acetate, and the organic layers were combined and dried with anhydrous Na2SO4. The dried organic layer was cooled and a black solid was precipitated. The solid was recrystallized with ethyl acetate to give 2.17 g of bright yellow crystals with a melting point of 142-144 °C and a yield of 81.2%.

References

[1] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 18, p. 2773 - 2778
[2] Patent: US5641789, 1997, A
[3] Patent: US2008/103307, 2008, A1. Location in patent: Page/Page column 17
[4] Patent: US5322847, 1994, A
[5] Patent: EP641792, 1995, A1

6-Hydroxy-chroman-4-one Preparation Products And Raw materials

Raw materials

6-Methoxy-4-chromanone

Preparation Products

6-Hydroxy-chroman-4-one Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Golden Pharma Co., Limited 		+undefined18958062155 sales@zjgoldpharm.com China 5899 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43333 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shandong Xingzhi Biological Medicine Co. LTD 18366166027 xingzhi@xingzhipharm.com China 135 58
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8667 57
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4769 55
Supplier Advantage
Alchem Pharmtech,Inc. 		58
Golden Pharma Co., Limited 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shandong Xingzhi Biological Medicine Co. LTD 58
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 56
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Guangzhou Isun Pharmaceutical Co., Ltd 55

6-Hydroxy-chroman-4-one Spectrum

6-Hydroxy-chroman-4-one(80096-64-6)1HNMR

80096-64-6(6-Hydroxy-chroman-4-one)Related Search:

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6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE 1'-benzyl-6-methoxyspiro[chroman-2,4'-piperidin]-4-one 6-Hydroxy-chroman-4-one 5,9,10-TRIMETHOXY-3,3-DIMETHYL-13,13A-DIHYDRO-3H,7AH-PYRANO[2,3-C:6,5-F']DICHROMEN-7-ONE 6,2'-DIHYDROXYFLAVANONE
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6-hydroxy-2,3-dihydrochroMen-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-6-hydroxy- 6-Hydroxy-4-chromanone 6-HYDROXY-CHROMAN-4-ONE 80096-64-6