NEOTROFIN
- CAS No.
- 192564-13-9
- Chemical Name:
- NEOTROFIN
- Synonyms
- SPI205;SPI-205;SPI 205;NEOTROFIN;Leteprinim potassium;Leteprinim Potassium Salt;Potassium,4-[3-(6-oxo-3H-purin-9-yl)propanoylamino]benzoate;4-{[3-(6-oxo-3,6-dihydro-9H-purin-9-yl)propanoyl]amino}benzoic acid;4-[[3-(1,6-Dihydro-6-oxo-9H-purin-9-yl)-1-oxopropyl]amino]benzoic Acid Potassium Salt;Benzoic acid, 4-[[3-(1,6-dihydro-6-oxo-9H-purin-9-yl)-1-oxopropyl]amino]-, potassium salt (1:1)
- CBNumber:
- CB41011492
- Molecular Formula:
- C15H12N5O4.K
- Molecular Weight:
- 365.389
- MDL Number:
- MFCD09763657
- MOL File:
- 192564-13-9.mol
| Melting point | 268-270°C (dec.) |
|---|---|
| storage temp. | Refrigerator |
| solubility | Water |
| form | Solid |
| color | Off White to Pale Yellow |
| FDA UNII | Q06WU8JY4F |
NEOTROFIN price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21748 | Leteprinim (potassium salt) | 192564-13-9 | 1mg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 21748 | Leteprinim (potassium salt) | 192564-13-9 | 5mg | $162 | 2024-03-01 | Buy |
| Cayman Chemical | 21748 | Leteprinim (potassium salt) | 192564-13-9 | 10mg | $263 | 2024-03-01 | Buy |
| Usbiological | 015530 | Leteprinim Potassium Salt | 192564-13-9 | 10mg | $403 | 2021-12-16 | Buy |
| TRC | L329900 | LeteprinimPotassiumSalt | 192564-13-9 | 100mg | $875 | 2021-12-16 | Buy |
NEOTROFIN Chemical Properties,Uses,Production
Chemical Properties
Off White to Pale Yellow Solid
Uses
A synthetic purine derivative with neuroprotective effects. A cognitive enhancer, is transported into brain by a nonsaturable influx mechanism and out of brain by a saturable efflux mechanism.
brand name
Neotrofin (NeoTherapeutics).
in vivo
Leteprinim (30 or 60 mg/kg, i.p., for 7 days) potassium protect rats against Kainate (12 mg/kg) induced excitotoxicity of hippocampal neurons[1].
Leteprinim (60 mg/kg, i.p.) potassium enhances working memory in young and aged mice[3].
Leteprinim (60 mg/kg; i.p.; single dosage) potassium significantly reduces the number of apoptotic neurons in hypoxic-ischemic brain injury rat pups[4].
| Animal Model: | Wistar rat pups (hypoxic-ischemic brain injury induced by permanent unilateral carotid ligation)[4] |
| Dosage: | 60 mg/kg |
| Administration: | IP; single dosage |
| Result: | The number of preserved neurons was significantly high in CA1, CA3 regions of hippocampus and dentate gyrus in the left hemispheres when compared with the saline-treated group. In the right hemisphere, neuronal densities of CA1, CA2, CA3 regions of hippocampus and dentate gyrus were significantly high in neotrofin treatment group when compared with the group given saline. |
NEOTROFIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jk.info@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9658 | 60 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8065 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
| Shanghai TenSus Biotechnology Co., Ltd. | 021-50895067 18616507272 | tensus@163.com | China | 7535 | 58 |
View Lastest Price from NEOTROFIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | Leteprinim potassium
192564-13-9
|
US $573.00-953.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Leteprinim potassium
192564-13-9
- US $573.00-953.00 / mg
- TargetMol Chemicals Inc.